ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
Orellana, Juan A., Froger, Nicolas, Ezan, Pascal, Jiang, Jean X., Bennett, Michael V. L., Naus, Christian C., Giaume, Christian, Sáez, Juan C.
Published in Journal of neurochemistry (01.09.2011)
Published in Journal of neurochemistry (01.09.2011)
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Journal Article
Connexin and pannexin hemichannels in inflammatory responses of glia and neurons
Bennett, Michael V.L, Garré, Juan M, Orellana, Juan A, Bukauskas, Felix F, Nedergaard, Maiken, Giaume, Christian, Sáez, Juan C
Published in Brain research (03.12.2012)
Published in Brain research (03.12.2012)
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Journal Article
Conference Proceeding
Gap junction channels and hemichannels in the CNS: Regulation by signaling molecules
Orellana, Juan A., Martinez, Agustín D., Retamal, Mauricio A.
Published in Neuropharmacology (01.12.2013)
Published in Neuropharmacology (01.12.2013)
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Journal Article
Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala
Stehberg, Jimmy, Moraga-Amaro, Rodrigo, Salazar, Christian, Becerra, Alvaro, Echeverría, Cesar, Orellana, Juan A, Bultynck, Geert, Ponsaerts, Raf, Leybaert, Luc, Simon, Felipe, Sáez, Juan C, Retamal, Mauricio A
Published in The FASEB journal (01.09.2012)
Published in The FASEB journal (01.09.2012)
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Journal Article
Amyloid β-induced death in neurons involves glial and neuronal hemichannels
Orellana, Juan A, Shoji, Kenji F, Abudara, Verónica, Ezan, Pascal, Amigou, Edwige, Sáez, Pablo J, Jiang, Jean X, Naus, Christian C, Sáez, Juan C, Giaume, Christian
Published in The Journal of neuroscience (30.03.2011)
Published in The Journal of neuroscience (30.03.2011)
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Journal Article
Glial connexin expression and function in the context of Alzheimer's disease
Koulakoff, Annette, Mei, Xin, Orellana, Juan A., Sáez, Juan C., Giaume, Christian
Published in Biochimica et biophysica acta (01.08.2012)
Published in Biochimica et biophysica acta (01.08.2012)
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Journal Article
Hypertensive Nephropathy: Unveiling the Possible Involvement of Hemichannels and Pannexons
Lucero, Claudia M, Prieto-Villalobos, Juan, Marambio-Ruiz, Lucas, Balmazabal, Javiera, Alvear, Tanhia F, Vega, Matías, Barra, Paola, Retamal, Mauricio A, Orellana, Juan A, Gómez, Gonzalo I
Published in International journal of molecular sciences (14.12.2022)
Published in International journal of molecular sciences (14.12.2022)
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Journal Article
Synaptic Functions of Hemichannels and Pannexons: A Double-Edged Sword
Abudara, Verónica, Retamal, Mauricio A, Del Rio, Rodrigo, Orellana, Juan A
Published in Frontiers in molecular neuroscience (04.12.2018)
Published in Frontiers in molecular neuroscience (04.12.2018)
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Journal Article
HIV gp120 Protein Increases the Function of Connexin 43 Hemichannels and Pannexin-1 Channels in Astrocytes: Repercussions on Astroglial Function
Gajardo-Gómez, Rosario, Santibañez, Cristian A, Labra, Valeria C, Gómez, Gonzalo I, Eugenin, Eliseo A, Orellana, Juan A
Published in International journal of molecular sciences (03.04.2020)
Published in International journal of molecular sciences (03.04.2020)
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Journal Article
Connexin 43 hemichannels and pannexin‐1 channels contribute to the α‐synuclein‐induced dysfunction and death of astrocytes
Díaz, Esteban F., Labra, Valeria C., Alvear, Tanhia F., Mellado, Luis A., Inostroza, Carla A., Oyarzún, Juan E., Salgado, Nicole, Quintanilla, Rodrigo A., Orellana, Juan A.
Published in Glia (01.08.2019)
Published in Glia (01.08.2019)
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Journal Article
Connexins and Pannexins: New Insights into Microglial Functions and Dysfunctions
Gajardo-Gómez, Rosario, Labra, Valeria C, Orellana, Juan A
Published in Frontiers in molecular neuroscience (22.09.2016)
Published in Frontiers in molecular neuroscience (22.09.2016)
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Journal Article
Hypoxia in high glucose followed by reoxygenation in normal glucose reduces the viability of cortical astrocytes through increased permeability of connexin 43 hemichannels
Orellana, Juan A., Hernández, Diego E., Ezan, Pascal, Velarde, Victoria, Bennett, Michael V. L., Giaume, Christian, Sáez, Juan C.
Published in Glia (01.02.2010)
Published in Glia (01.02.2010)
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Journal Article
Glucose increases intracellular free Ca2+ in tanycytes via ATP released through connexin 43 hemichannels
Orellana, Juan A., Sáez, Pablo J., Cortés-campos, Christian, Elizondo, Roberto J., Shoji, Kenji F., Contreras-Duarte, Susana, Figueroa, Vania, Velarde, Victoria, Jiang, Jean X., Nualart, Francisco, Sáez, Juan C., García, María A.
Published in Glia (01.01.2012)
Published in Glia (01.01.2012)
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Journal Article
Prenatal exposure to inflammatory conditions increases Cx43 and Panx1 unopposed channel opening and activation of astrocytes in the offspring effect on neuronal survival
Avendaño, Beatriz C., Montero, Trinidad D., Chávez, Carolina E., von Bernhardi, Rommy, Orellana, Juan A.
Published in Glia (01.11.2015)
Published in Glia (01.11.2015)
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Journal Article
Interferon-γ and high glucose-induced opening of Cx43 hemichannels causes endothelial cell dysfunction and damage
Sáez, Juan C., Contreras-Duarte, Susana, Labra, Valeria C., Santibañez, Cristian A., Mellado, Luis A., Inostroza, Carla A., Alvear, Tanhia F., Retamal, Mauricio A., Velarde, Victoria, Orellana, Juan A.
Published in Biochimica et biophysica acta. Molecular cell research (01.08.2020)
Published in Biochimica et biophysica acta. Molecular cell research (01.08.2020)
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Journal Article
GABAergic Regulation of Astroglial Gliotransmission through Cx43 Hemichannels
Jiménez-Dinamarca, Ivanka, Reyes-Lizana, Rachel, Lemunao-Inostroza, Yordan, Cárdenas, Kevin, Castro-Lazo, Raimundo, Peña, Francisca, Lucero, Claudia M., Prieto-Villalobos, Juan, Retamal, Mauricio Antonio, Orellana, Juan Andrés, Stehberg, Jimmy
Published in International journal of molecular sciences (01.11.2022)
Published in International journal of molecular sciences (01.11.2022)
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Journal Article