Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
Patel, Siddharth, Ashwanikumar, N, Robinson, Ema, Xia, Yan, Mihai, Cosmin, Griffith, 3rd, Joseph P, Hou, Shangguo, Esposito, Adam A, Ketova, Tatiana, Welsher, Kevin, Joyal, John L, Almarsson, Örn, Sahay, Gaurav
Published in Nature communications (20.02.2020)
Published in Nature communications (20.02.2020)
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Journal Article
Impact of mRNA chemistry and manufacturing process on innate immune activation
Nelson, Jennifer, Sorensen, Elizabeth W, Mintri, Shrutika, Rabideau, Amy E, Zheng, Wei, Besin, Gilles, Khatwani, Nikhil, Su, Stephen V, Miracco, Edward J, Issa, William J, Hoge, Stephen, Stanton, Matthew G, Joyal, John L
Published in Science advances (01.06.2020)
Published in Science advances (01.06.2020)
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First-in-man evaluation of 2 high-affinity PSMA-avid small molecules for imaging prostate cancer
Barrett, John A, Coleman, R Edward, Goldsmith, Stanley J, Vallabhajosula, Shankar, Petry, Neil A, Cho, Steve, Armor, Thomas, Stubbs, James B, Maresca, Kevin P, Stabin, Michael G, Joyal, John L, Eckelman, William C, Babich, John W
Published in Journal of Nuclear Medicine (01.03.2013)
Published in Journal of Nuclear Medicine (01.03.2013)
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Journal Article
Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes
Gan, Li-Ming, Lagerström-Fermér, Maria, Carlsson, Leif G, Arfvidsson, Cecilia, Egnell, Ann-Charlotte, Rudvik, Anna, Kjaer, Magnus, Collén, Anna, Thompson, James D, Joyal, John, Chialda, Ligia, Koernicke, Thomas, Fuhr, Rainard, Chien, Kenneth R, Fritsche-Danielson, Regina
Published in Nature communications (20.02.2019)
Published in Nature communications (20.02.2019)
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Journal Article
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen: pharmacokinetics and biodistribution studies in healthy subjects and patients with metastatic prostate cancer
Vallabhajosula, Shankar, Nikolopoulou, Anastasia, Babich, John W, Osborne, Joseph R, Tagawa, Scott T, Lipai, Irina, Solnes, Lilja, Maresca, Kevin P, Armor, Thomas, Joyal, John L, Crummet, Robert, Stubbs, James B, Goldsmith, Stanley J
Published in The Journal of nuclear medicine (1978) (01.11.2014)
Published in The Journal of nuclear medicine (1978) (01.11.2014)
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Journal Article
Preclinical Evaluation of Novel Glutamate-Urea-Lysine Analogues That Target Prostate-Specific Membrane Antigen as Molecular Imaging Pharmaceuticals for Prostate Cancer
HILLIER, Shawn M, MARESCA, Kevin P, JOYAL, John L, BABICH, John W, FEMIA, Frank J, MARQUIS, John C, FOSS, Catherine A, NGUYEN, Nghi, ZIMMERMAN, Craig N, BARRETT, John A, ECKELMAN, William C, POMPER, Martin G
Published in Cancer research (Chicago, Ill.) (01.09.2009)
Published in Cancer research (Chicago, Ill.) (01.09.2009)
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Author Correction: Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
Patel, Siddharth, Ashwanikumar, N., Robinson, Ema, Xia, Yan, Mihai, Cosmin, Griffith, Joseph P., Hou, Shangguo, Esposito, Adam A., Ketova, Tatiana, Welsher, Kevin, Joyal, John L., Almarsson, Örn, Sahay, Gaurav
Published in Nature communications (06.07.2020)
Published in Nature communications (06.07.2020)
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Journal Article
Atypical Antipsychotics Rapidly and Inappropriately Switch Peripheral Fuel Utilization to Lipids, Impairing Metabolic Flexibility in Rodents
Albaugh, Vance L., Vary, Thomas C., Ilkayeva, Olga, Wenner, Brett R., Maresca, Kevin P., Joyal, John L., Breazeale, Steven, Elich, Tedd D., Lang, Charles H., Lynch, Christopher J.
Published in Schizophrenia bulletin (01.01.2012)
Published in Schizophrenia bulletin (01.01.2012)
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Molecular Imaging of Human ACE-1 Expression in Transgenic Rats
Dilsizian, Vasken, MD, Zynda, Todd K., DO, Petrov, Artiom, PhD, Ohshima, Satoru, MD, PhD, Tahara, Nobuhiro, MD, PhD, Haider, Nezam, PhD, Donohue, Amanda, DO, Aras, Omer, MD, Femia, Frank J., PhD, Hillier, Shawn M., PhD, Joyal, John L., PhD, Wong, Nathan D., PhD, Coleman, Tomika, MS, Babich, John W., PhD, Narula, Jagat, MD, PhD
Published in JACC. Cardiovascular imaging (01.04.2012)
Published in JACC. Cardiovascular imaging (01.04.2012)
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Journal Article
Novel Polar Single Amino Acid Chelates for Technetium-99m Tricarbonyl-Based Radiopharmaceuticals with Enhanced Renal Clearance: Application to Octreotide
Maresca, Kevin P, Marquis, John C, Hillier, Shawn M, Lu, Genliang, Femia, Frank J, Zimmerman, Craig N, Eckelman, William C, Joyal, John L, Babich, John W
Published in Bioconjugate chemistry (16.06.2010)
Published in Bioconjugate chemistry (16.06.2010)
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Journal Article
Synthesis, cytotoxicity and cellular uptake studies of N3 functionalized Re(CO)3 thymidine complexes
Bartholomä, Mark D, Vortherms, Anthony R, Hillier, Shawn, Joyal, John, Babich, John, Doyle, Robert P, Zubieta, Jon
Published in Dalton transactions : an international journal of inorganic chemistry (21.06.2011)
Published in Dalton transactions : an international journal of inorganic chemistry (21.06.2011)
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Journal Article
Comprehensive Radiolabeling, Stability, and Tissue Distribution Studies of Technetium-99m Single Amino Acid Chelates (SAAC)
Maresca, Kevin P, Hillier, Shawn M, Femia, Frank J, Zimmerman, Craig N, Levadala, Murali K, Banerjee, Sangeeta R, Hicks, Justin, Sundararajan, Chitra, Valliant, John, Zubieta, Jon, Eckelman, William C, Joyal, John L, Babich, John W
Published in Bioconjugate chemistry (19.08.2009)
Published in Bioconjugate chemistry (19.08.2009)
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Journal Article
Comparison of high-specific-activity ultratrace [sup.123/131]I-MIBG and carrier-added [sup.123/131]I-MIBG on efficacy, pharmacokinetics, and tissue distribution
Barrett, John A, Joyal, John L, Hillier, Shawn M, Maresca, Kevin P, Femia, Frank J, Kronauge, James F, Boyd, Marie, Mairs, Robert J, Babich, John W
Published in Cancer biotherapy & radiopharmaceuticals (01.06.2010)
Published in Cancer biotherapy & radiopharmaceuticals (01.06.2010)
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Journal Article
Diagnostic and therapeutic imaging for cancer: Therapeutic considerations and future directions
Roach III, Mack, Alberini, Jean-Louis, Pecking, Alain Paul, Testori, Alessandro, Verrecchia, Francesco, Soteldo, Javier, Ganswindt, Ute, Joyal, John L., Babich, John W., Witte, Russell S., Unger, Evan, Gottlieb, Ronald
Published in Journal of surgical oncology (01.05.2011)
Published in Journal of surgical oncology (01.05.2011)
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Journal Article
Triazole Appending Agent (TAAG): A New Synthon for Preparing Iodine-Based Molecular Imaging and Radiotherapy Agents
Darwish, Alla, Blacker, Megan, Janzen, Nancy, Rathmann, Stephanie M, Czorny, Shannon, Hillier, Shawn M, Joyal, John L, Babich, John W, Valliant, John F
Published in ACS medicinal chemistry letters (12.04.2012)
Published in ACS medicinal chemistry letters (12.04.2012)
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Journal Article
Synthesis and SAR of 99mTc/Re-labeled small molecule prostate specific membrane antigen inhibitors with novel polar chelates
Lu, Genliang, Maresca, Kevin P., Hillier, Shawn M., Zimmerman, Craig N., Eckelman, William C., Joyal, John L., Babich, John W.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Journal Article
Justifying the number of animals for each experiment
Eckelman, William C., PhD, Kilbourn, Michael R., PhD, Joyal, John L., PhD, Labiris, Renée, PhD, Valliant, John F., PhD
Published in Nuclear medicine and biology (01.04.2007)
Published in Nuclear medicine and biology (01.04.2007)
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Journal Article
Stimulation of enveloped virus infection by beta-amyloid fibrils
Wojtowicz, Woj M, Farzan, Michael, Joyal, John L, Carter, Kara, Babcock, Gregory J, Israel, David I, Sodroski, Joseph, Mirzabekov, Tajib
Published in The Journal of biological chemistry (20.09.2002)
Published in The Journal of biological chemistry (20.09.2002)
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Journal Article
Preclinical Evaluation of an 131I-Labeled Benzamide for Targeted Radiotherapy of Metastatic Melanoma
JOYAL, John L, BARRETT, John A, FRIEBE, Matthias, DINKELBORG, Ludger, STUBBS, James B, STABIN, Michael G, MAIRS, Rob, POMPER, Martin G, BABICH, John W, MARQUIS, John C, JIANQING CHEN, HILLER, Shawn M, MARESCA, Kevin P, BOYD, Marie, GAGE, Kenneth, NIMMAGADDA, Sridhar, KRONAUGE, James F
Published in Cancer research (Chicago, Ill.) (15.05.2010)
Published in Cancer research (Chicago, Ill.) (15.05.2010)
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Second-generation single-amino-acid chelate technology with enhanced hydrophilicity: development and successful application to molecular imaging
Maresca, Kevin P, Hillier, Shawn M, Lu, Genliang, Marquis, John C, Zimmerman, Craig N, Eckelman, William C, Joyal, John L, Babich, John W
Published in Nuclear medicine and biology (2010)
Published in Nuclear medicine and biology (2010)
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