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Unoh, Yuto, Uehara, Shota, Nakahara, Kenji, Nobori, Haruaki, Yamatsu, Yukiko, Yamamoto, Shiho, Maruyama, Yuki, Taoda, Yoshiyuki, Kasamatsu, Koji, Suto, Takahiro, Kouki, Kensuke, Nakahashi, Atsufumi, Kawashima, Sho, Sanaki, Takao, Toba, Shinsuke, Uemura, Kentaro, Mizutare, Tohru, Ando, Shigeru, Sasaki, Michihito, Orba, Yasuko, Sawa, Hirofumi, Sato, Akihiko, Sato, Takafumi, Kato, Teruhisa, Tachibana, Yuki
Published in Journal of medicinal chemistry (12.05.2022)
Published in Journal of medicinal chemistry (12.05.2022)
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Published in Journal of medicinal chemistry (27.08.2020)
Published in Journal of medicinal chemistry (27.08.2020)
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Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight
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Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
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Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CLProtease Inhibitor Clinical Candidate for Treating COVID-19
Unoh, Yuto, Uehara, Shota, Nakahara, Kenji, Nobori, Haruaki, Yamatsu, Yukiko, Yamamoto, Shiho, Maruyama, Yuki, Taoda, Yoshiyuki, Kasamatsu, Koji, Suto, Takahiro, Kouki, Kensuke, Nakahashi, Atsufumi, Kawashima, Sho, Sanaki, Takao, Toba, Shinsuke, Uemura, Kentaro, Mizutare, Tohru, Ando, Shigeru, Sasaki, Michihito, Orba, Yasuko, Sawa, Hirofumi, Sato, Akihiko, Sato, Takafumi, Kato, Teruhisa, Tachibana, Yuki
Published in Journal of medicinal chemistry (12.05.2022)
Published in Journal of medicinal chemistry (12.05.2022)
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α‑Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment
Zhang, Linlin, Lin, Daizong, Kusov, Yuri, Nian, Yong, Ma, Qingjun, Wang, Jiang, von Brunn, Albrecht, Leyssen, Pieter, Lanko, Kristina, Neyts, Johan, de Wilde, Adriaan, Snijder, Eric J, Liu, Hong, Hilgenfeld, Rolf
Published in Journal of Medicinal Chemistry (14.05.2020)
Published in Journal of Medicinal Chemistry (14.05.2020)
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Johnson, Benjamin M, Shu, Yue-Zhong, Zhuo, Xiaoliang, Meanwell, Nicholas A
Published in Journal of medicinal chemistry (25.06.2020)
Published in Journal of medicinal chemistry (25.06.2020)
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COVID-19: Drug Targets and Potential Treatments
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Published in Journal of Medicinal Chemistry (12.11.2020)
Published in Journal of Medicinal Chemistry (12.11.2020)
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Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19
Hoffman, Robert L, Kania, Robert S, Brothers, Mary A, Davies, Jay F, Ferre, Rose A, Gajiwala, Ketan S, He, Mingying, Hogan, Robert J, Kozminski, Kirk, Li, Lilian Y, Lockner, Jonathan W, Lou, Jihong, Marra, Michelle T, Mitchell, Lennert J, Murray, Brion W, Nieman, James A, Noell, Stephen, Planken, Simon P, Rowe, Thomas, Ryan, Kevin, Smith, George J, Solowiej, James E, Steppan, Claire M, Taggart, Barbara
Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
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Amide Bond Bioisosteres: Strategies, Synthesis, and Successes
Kumari, Shikha, Carmona, Angelica V, Tiwari, Amit K, Trippier, Paul C
Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
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Applications of Deuterium in Medicinal Chemistry
Pirali, Tracey, Serafini, Marta, Cargnin, Sarah, Genazzani, Armando A
Published in Journal of medicinal chemistry (13.06.2019)
Published in Journal of medicinal chemistry (13.06.2019)
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Spirocyclic Scaffolds in Medicinal Chemistry
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Published in Journal of medicinal chemistry (14.01.2021)
Published in Journal of medicinal chemistry (14.01.2021)
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The Current State of Peptide Drug Discovery: Back to the Future?
Henninot, Antoine, Collins, James C, Nuss, John M
Published in Journal of medicinal chemistry (22.02.2018)
Published in Journal of medicinal chemistry (22.02.2018)
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Identification of the Clinical Development Candidate MRTX849, a Covalent KRAS(G12C) Inhibitor for the Treatment of Cancer
Fell, Jay B., Fischer, John P., Baer, Brian R., Blake, James F., Bouhana, Karyn, Briere, David M., Brown, Karin D., Burgess, Laurence E., Burns, Aaron C., Burkard, Michael R., Chiang, Harrah, Chicarelli, Mark J., Cook, Adam W., Gaudino, John J., Hallin, Jill, Hanson, Lauren, Hartley, Dylan P., Hicken, Erik J., Hingorani, Gary P., Hinklin, Ronald J., Mejia, Macedonio J., Olson, Peter, Otten, Jennifer N., Rhodes, Susan P., Rodriguez, Martha E., Savechenkov, Pavel, Smith, Darin J., Sudhakar, Niranjan, Sullivan, Francis X., Tang, Tony P., Vigers, Guy P., Wollenberg, Lance, Christensen, James G., Marx, Matthew A.
Published in Journal of medicinal chemistry (09.07.2020)
Published in Journal of medicinal chemistry (09.07.2020)
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The Essential Medicinal Chemistry of Curcumin
Nelson, Kathryn M, Dahlin, Jayme L, Bisson, Jonathan, Graham, James, Pauli, Guido F, Walters, Michael A
Published in Journal of medicinal chemistry (09.03.2017)
Published in Journal of medicinal chemistry (09.03.2017)
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Applications of Fluorine in Medicinal Chemistry
Gillis, Eric P, Eastman, Kyle J, Hill, Matthew D, Donnelly, David J, Meanwell, Nicholas A
Published in Journal of medicinal chemistry (12.11.2015)
Published in Journal of medicinal chemistry (12.11.2015)
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Nitro-Group-Containing Drugs
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Published in Journal of medicinal chemistry (28.03.2019)
Published in Journal of medicinal chemistry (28.03.2019)
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