Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
Joung, Julia, Konermann, Silvana, Gootenberg, Jonathan S, Abudayyeh, Omar O, Platt, Randall J, Brigham, Mark D, Sanjana, Neville E, Zhang, Feng
Published in Nature protocols (01.04.2017)
Published in Nature protocols (01.04.2017)
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Journal Article
High-resolution interrogation of functional elements in the noncoding genome
Sanjana, Neville E., Wright, Jason, Zheng, Kaijie, Shalem, Ophir, Fontanillas, Pierre, Joung, Julia, Cheng, Christine, Regev, Aviv, Zhang, Feng
Published in Science (American Association for the Advancement of Science) (30.09.2016)
Published in Science (American Association for the Advancement of Science) (30.09.2016)
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Journal Article
A cytosine deaminase for programmable single-base RNA editing
Abudayyeh, Omar O, Gootenberg, Jonathan S, Franklin, Brian, Koob, Jeremy, Kellner, Max J, Ladha, Alim, Joung, Julia, Kirchgatterer, Paul, Cox, David B T, Zhang, Feng
Published in Science (American Association for the Advancement of Science) (26.07.2019)
Published in Science (American Association for the Advancement of Science) (26.07.2019)
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Journal Article
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
Abudayyeh, Omar O., Gootenberg, Jonathan S., Konermann, Silvana, Joung, Julia, Slaymaker, Ian M., Cox, David B. T., Shmakov, Sergey, Makarova, Kira S., Semenova, Ekaterina, Minakhin, Leonid, Severinov, Konstantin, Regev, Aviv, Lander, Eric S., Koonin, Eugene V., Zhang, Feng
Published in Science (American Association for the Advancement of Science) (05.08.2016)
Published in Science (American Association for the Advancement of Science) (05.08.2016)
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Journal Article
Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes
Chung, Won-Suk, Verghese, Philip B., Chakraborty, Chandrani, Joung, Julia, Hyman, Bradley T., Ulrich, Jason D., Holtzman, David M., Barres, Ben A.
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
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Journal Article
CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity
Joung, Julia, Kirchgatterer, Paul C., Singh, Ankita, Cho, Jang H., Nety, Suchita P., Larson, Rebecca C., Macrae, Rhiannon K., Deasy, Rebecca, Tseng, Yuen-Yi, Maus, Marcela V., Zhang, Feng
Published in Nature communications (25.03.2022)
Published in Nature communications (25.03.2022)
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Journal Article
Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay
Schermer, Bernhard, Fabretti, Francesca, Damagnez, Maximilian, Di Cristanziano, Veronica, Heger, Eva, Arjune, Sita, Tanner, Nathan A, Imhof, Thomas, Koch, Manuel, Ladha, Alim, Joung, Julia, Gootenberg, Jonathan S, Abudayyeh, Omar O, Burst, Volker, Zhang, Feng, Klein, Florian, Benzing, Thomas, Müller, Roman-Ulrich
Published in PloS one (02.11.2020)
Published in PloS one (02.11.2020)
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Journal Article
Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma
Nie, Man, Du, Likun, Ren, Weicheng, Joung, Julia, Ye, Xiaofei, Shi, Xi, Ciftci, Sibel, Liu, Dongbing, Wu, Kui, Zhang, Feng, Pan-Hammarström, Qiang
Published in Cell death & disease (28.04.2021)
Published in Cell death & disease (28.04.2021)
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Journal Article
Application of CRISPR genetic screens to investigate neurological diseases
So, Raphaella W L, Chung, Sai Wai, Lau, Heather H C, Watts, Jeremy J, Gaudette, Erin, Al-Azzawi, Zaid A M, Bishay, Jossana, Lin, Lilian Tsai-Wei, Joung, Julia, Wang, Xinzhu, Schmitt-Ulms, Gerold
Published in Molecular neurodegeneration (14.11.2019)
Published in Molecular neurodegeneration (14.11.2019)
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Journal Article
221 CRISPR screen identifies loss of IFNγR signaling and downstream adhesion as a resistance mechanism to CAR T-cell cytotoxicity in solid but not liquid tumors
Larson, Rebecca, Kann, Michael, Bailey, Stefanie, Haradhvala, Nicholas, Stewart, Kai, Bouffard, Amanda, Scarfo, Irene, Leick, Mark, Berger, Trisha, Jan, Max, Joung, Julia, Ouspenskaia, Tamara, Law, Travis, Regev, Aviv, Getz, Gad, Maus, Marcela
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
Gootenberg, Jonathan S, Abudayyeh, Omar O, Kellner, Max J, Joung, Julia, Collins, James J, Zhang, Feng
Published in Science (American Association for the Advancement of Science) (27.04.2018)
Published in Science (American Association for the Advancement of Science) (27.04.2018)
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Journal Article
CRISPR technologies for genome, epigenome and transcriptome editing
Villiger, Lukas, Joung, Julia, Koblan, Luke, Weissman, Jonathan, Abudayyeh, Omar O., Gootenberg, Jonathan S.
Published in Nature reviews. Molecular cell biology (01.06.2024)
Published in Nature reviews. Molecular cell biology (01.06.2024)
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Journal Article
RNA editing with CRISPR-Cas13
Cox, David B. T., Gootenberg, Jonathan S., Abudayyeh, Omar O., Franklin, Brian, Kellner, Max J., Joung, Julia, Zhang, Feng
Published in Science (American Association for the Advancement of Science) (24.11.2017)
Published in Science (American Association for the Advancement of Science) (24.11.2017)
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Journal Article
Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
Dahlman, James E, Abudayyeh, Omar O, Joung, Julia, Gootenberg, Jonathan S, Zhang, Feng, Konermann, Silvana
Published in Nature biotechnology (01.11.2015)
Published in Nature biotechnology (01.11.2015)
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Journal Article
Nucleic acid detection with CRISPR-Cas13a/C2c2
Gootenberg, Jonathan S., Abudayyeh, Omar O., Lee, Jeong Wook, Essletzbichler, Patrick, Dy, Aaron J., Joung, Julia, Verdine, Vanessa, Donghia, Nina, Daringer, Nichole M., Freije, Catherine A., Myhrvold, Cameron, Bhattacharyya, Roby P., Livny, Jonathan, Regev, Aviv, Koonin, Eugene V., Hung, Deborah T., Sabeti, Pardis C., Collins, James J., Zhang, Feng
Published in Science (American Association for the Advancement of Science) (28.04.2017)
Published in Science (American Association for the Advancement of Science) (28.04.2017)
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Journal Article
RNA targeting with CRISPR–Cas13
Abudayyeh, Omar O., Gootenberg, Jonathan S., Essletzbichler, Patrick, Han, Shuo, Joung, Julia, Belanto, Joseph J., Verdine, Vanessa, Cox, David B. T., Kellner, Max J., Regev, Aviv, Lander, Eric S., Voytas, Daniel F., Ting, Alice Y., Zhang, Feng
Published in Nature (London) (12.10.2017)
Published in Nature (London) (12.10.2017)
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Journal Article
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Joung, Julia, Abudayyeh, Omar O., Barcena, Clea, Hsu, Patrick D., Habib, Naomi, Gootenberg, Jonathan S., Nishimasu, Hiroshi, Nureki, Osamu, Zhang, Feng
Published in Nature (London) (29.01.2015)
Published in Nature (London) (29.01.2015)
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Journal Article
Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems
Shmakov, Sergey, Abudayyeh, Omar O., Makarova, Kira S., Wolf, Yuri I., Gootenberg, Jonathan S., Semenova, Ekaterina, Minakhin, Leonid, Joung, Julia, Konermann, Silvana, Severinov, Konstantin, Zhang, Feng, Koonin, Eugene V.
Published in Molecular cell (05.11.2015)
Published in Molecular cell (05.11.2015)
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Journal Article
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Zetsche, Bernd, Gootenberg, Jonathan S., Abudayyeh, Omar O., Slaymaker, Ian M., Makarova, Kira S., Essletzbichler, Patrick, Volz, Sara E., Joung, Julia, van der Oost, John, Regev, Aviv, Koonin, Eugene V., Zhang, Feng
Published in Cell (22.10.2015)
Published in Cell (22.10.2015)
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Journal Article
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours
Larson, Rebecca C., Kann, Michael C., Bailey, Stefanie R., Haradhvala, Nicholas J., Llopis, Paula Montero, Bouffard, Amanda A., Scarfó, Irene, Leick, Mark B., Grauwet, Korneel, Berger, Trisha R., Stewart, Kai, Anekal, Praju Vikas, Jan, Max, Joung, Julia, Schmidts, Andrea, Ouspenskaia, Tamara, Law, Travis, Regev, Aviv, Getz, Gad, Maus, Marcela V.
Published in Nature (London) (21.04.2022)
Published in Nature (London) (21.04.2022)
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Journal Article