CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
Kurt, Ibrahim C, Zhou, Ronghao, Iyer, Sowmya, Garcia, Sara P, Miller, Bret R, Langner, Lukas M, Grünewald, Julian, Joung, J Keith
Published in Nature biotechnology (01.01.2021)
Published in Nature biotechnology (01.01.2021)
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Gene therapy comes of age
Dunbar, Cynthia E, High, Katherine A, Joung, J Keith, Kohn, Donald B, Ozawa, Keiya, Sadelain, Michel
Published in Science (American Association for the Advancement of Science) (12.01.2018)
Published in Science (American Association for the Advancement of Science) (12.01.2018)
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CRISPResso2 provides accurate and rapid genome editing sequence analysis
Clement, Kendell, Rees, Holly, Canver, Matthew C, Gehrke, Jason M, Farouni, Rick, Hsu, Jonathan Y, Cole, Mitchel A, Liu, David R, Joung, J Keith, Bauer, Daniel E, Pinello, Luca
Published in Nature biotechnology (01.03.2019)
Published in Nature biotechnology (01.03.2019)
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PrimeDesign software for rapid and simplified design of prime editing guide RNAs
Hsu, Jonathan Y, Grünewald, Julian, Szalay, Regan, Shih, Justine, Anzalone, Andrew V, Lam, Kin Chung, Shen, Max W, Petri, Karl, Liu, David R, Joung, J Keith, Pinello, Luca
Published in Nature communications (15.02.2021)
Published in Nature communications (15.02.2021)
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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Tsai, Shengdar Q, Zheng, Zongli, Nguyen, Nhu T, Liebers, Matthew, Topkar, Ved V, Thapar, Vishal, Wyvekens, Nicolas, Khayter, Cyd, Iafrate, A John, Le, Long P, Aryee, Martin J, Joung, J Keith
Published in Nature biotechnology (01.02.2015)
Published in Nature biotechnology (01.02.2015)
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Adopt a moratorium on heritable genome editing
Lander, Eric S, Baylis, Françoise, Zhang, Feng, Charpentier, Emmanuelle, Berg, Paul, Bourgain, Catherine, Friedrich, Bärbel, Joung, J Keith, Li, Jinsong, Liu, David, Naldini, Luigi, Nie, Jing-Bao, Qiu, Renzong, Schoene-Seifert, Bettina, Shao, Feng, Terry, Sharon, Wei, Wensheng, Winnacker, Ernst-Ludwig
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
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Therapeutic base editing of human hematopoietic stem cells
Zeng, Jing, Wu, Yuxuan, Ren, Chunyan, Bonanno, Jasmine, Shen, Anne H, Shea, Devlin, Gehrke, Jason M, Clement, Kendell, Luk, Kevin, Yao, Qiuming, Kim, Rachel, Wolfe, Scot A, Manis, John P, Pinello, Luca, Joung, J Keith, Bauer, Daniel E
Published in Nature medicine (01.04.2020)
Published in Nature medicine (01.04.2020)
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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Fu, Yanfang, Sander, Jeffry D, Reyon, Deepak, Cascio, Vincent M, Joung, J Keith
Published in Nature biotechnology (01.03.2014)
Published in Nature biotechnology (01.03.2014)
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Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
Kleinstiver, Benjamin P, Tsai, Shengdar Q, Prew, Michelle S, Nguyen, Nhu T, Welch, Moira M, Lopez, Jose M, McCaw, Zachary R, Aryee, Martin J, Joung, J Keith
Published in Nature biotechnology (01.08.2016)
Published in Nature biotechnology (01.08.2016)
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Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
Grünewald, Julian, Zhou, Ronghao, Garcia, Sara P, Iyer, Sowmya, Lareau, Caleb A, Aryee, Martin J, Joung, J Keith
Published in Nature (London) (01.05.2019)
Published in Nature (London) (01.05.2019)
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Heritable and precise zebrafish genome editing using a CRISPR-Cas system
Hwang, Woong Y, Fu, Yanfang, Reyon, Deepak, Maeder, Morgan L, Kaini, Prakriti, Sander, Jeffry D, Joung, J Keith, Peterson, Randall T, Yeh, Jing-Ruey Joanna
Published in PloS one (09.07.2013)
Published in PloS one (09.07.2013)
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Discovery of widespread type I and type V CRISPR-Cas inhibitors
Marino, Nicole D, Zhang, Jenny Y, Borges, Adair L, Sousa, Alexander A, Leon, Lina M, Rauch, Benjamin J, Walton, Russell T, Berry, Joel D, Joung, J Keith, Kleinstiver, Benjamin P, Bondy-Denomy, Joseph
Published in Science (American Association for the Advancement of Science) (12.10.2018)
Published in Science (American Association for the Advancement of Science) (12.10.2018)
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Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
Kleinstiver, Benjamin P, Sousa, Alexander A, Walton, Russell T, Tak, Y Esther, Hsu, Jonathan Y, Clement, Kendell, Welch, Moira M, Horng, Joy E, Malagon-Lopez, Jose, Scarfò, Irene, Maus, Marcela V, Pinello, Luca, Aryee, Martin J, Joung, J Keith
Published in Nature biotechnology (01.03.2019)
Published in Nature biotechnology (01.03.2019)
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Journal Article
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells
Petri, Karl, Zhang, Weiting, Ma, Junyan, Schmidts, Andrea, Lee, Hyunho, Horng, Joy E, Kim, Daniel Y, Kurt, Ibrahim C, Clement, Kendell, Hsu, Jonathan Y, Pinello, Luca, Maus, Marcela V, Joung, J Keith, Yeh, Jing-Ruey Joanna
Published in Nature biotechnology (01.02.2022)
Published in Nature biotechnology (01.02.2022)
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