Site-Directed Mutagenesis at the Molybdenum Pterin Cofactor Site of the Human Aldehyde Oxidase: Interrogating the Kinetic Differences Between Human and Cynomolgus Monkey
Abbasi, Armina, Joswig-Jones, Carolyn A, Jones, Jeffrey P
Published in Drug metabolism and disposition (01.12.2020)
Published in Drug metabolism and disposition (01.12.2020)
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Journal Article
Why do most human liver cytosol preparations lack xanthine oxidase activity?
Barr, John T, Choughule, Kanika V, Nepal, Sahadev, Wong, Timothy, Chaudhry, Amarjit S, Joswig-Jones, Carolyn A, Zientek, Michael, Strom, Stephen C, Schuetz, Erin G, Thummel, Kenneth E, Jones, Jeffrey P
Published in Drug metabolism and disposition (01.04.2014)
Published in Drug metabolism and disposition (01.04.2014)
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Journal Article
ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism
Paragas, Erickson M, Humphreys, Sara C, Min, Joshua, Joswig-Jones, Carolyn A, Leimkühler, Silke, Jones, Jeffrey P
Published in ACS omega (31.08.2017)
Published in ACS omega (31.08.2017)
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Journal Article
Time Course of Aldehyde Oxidase and Why It Is Nonlinear
Abbasi, Armina, Paragas, Erickson M, Joswig-Jones, Carolyn A, Rodgers, John T, Jones, Jeffrey P
Published in Drug metabolism and disposition (01.05.2019)
Published in Drug metabolism and disposition (01.05.2019)
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Journal Article
In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase
Choughule, Kanika V, Barnaba, Carlo, Joswig-Jones, Carolyn A, Jones, Jeffrey P
Published in Drug metabolism and disposition (01.08.2014)
Published in Drug metabolism and disposition (01.08.2014)
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Journal Article
Synthesis and Biological Activity of Novel 5-Fluoro-2‘-deoxyuridine Phosphoramidate Prodrugs
Freel Meyers, Caren L, Hong, Liping, Joswig, Carolyn, Borch, Richard F
Published in Journal of medicinal chemistry (02.11.2000)
Published in Journal of medicinal chemistry (02.11.2000)
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Journal Article
Synthesis and Evaluation of Nitroheterocyclic Phosphoramidates as Hypoxia-Selective Alkylating Agents
Borch, Richard F, Liu, Jiwen, Schmidt, James P, Marakovits, Joseph T, Joswig, Carolyn, Gipp, Jerry J, Mulcahy, R. Timothy
Published in Journal of medicinal chemistry (01.06.2000)
Published in Journal of medicinal chemistry (01.06.2000)
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Journal Article
The kinetic mechanism for cytochrome P450 metabolism of Type II binding compounds: Evidence supporting direct reduction
Pearson, Joshua, Dahal, Upendra P., Rock, Daniel, Peng, Chi-Chi, Schenk, James O., Joswig-Jones, Carolyn, Jones, Jeffrey P.
Published in Archives of biochemistry and biophysics (01.07.2011)
Published in Archives of biochemistry and biophysics (01.07.2011)
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Antitumor Activity and Toxicity of Novel Nitroheterocyclic Phosphoramidates
Borch, Richard F, Liu, Jiwen, Joswig, Carolyn, Baggs, Raymond B, Dexter, Daniel L, Mangold, Gina L
Published in Journal of medicinal chemistry (04.01.2001)
Published in Journal of medicinal chemistry (04.01.2001)
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Journal Article
Synthesis and Biological Evaluation of 5-Fluoro-2'-deoxyuridine Phosphoramidate Analogs
Fries, Kristin M, Joswig, Carolyn, Borch, Richard F
Published in Journal of medicinal chemistry (01.07.1995)
Published in Journal of medicinal chemistry (01.07.1995)
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Journal Article
Nitrobenzyl Phosphorodiamidates as Potential Hypoxia-Selective Alkylating Agents
Mulcahy, R. Timothy, Gipp, Jerry J, Schmidt, James P, Joswig, Carolyn, Borch, Richard F
Published in Journal of medicinal chemistry (01.05.1994)
Published in Journal of medicinal chemistry (01.05.1994)
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