Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells
Schillemans, Maaike, Karampini, Ellie, van den Eshof, Bart L, Gangaev, Anastasia, Hofman, Menno, van Breevoort, Dorothee, Meems, Henriët, Janssen, Hans, Mulder, Aat A, Jost, Carolina R, Escher, Johanna C, Adam, Rüdiger, Carter, Tom, Koster, Abraham J, van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2018)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2018)
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Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5
Quinn, Peter M., Buck, Thilo M., Mulder, Aat A., Ohonin, Charlotte, Alves, C. Henrique, Vos, Rogier M., Bialecka, Monika, van Herwaarden, Tessa, van Dijk, Elon H.C., Talib, Mays, Freund, Christian, Mikkers, Harald M.M., Hoeben, Rob C., Goumans, Marie-José, Boon, Camiel J.F., Koster, Abraham J., Chuva de Sousa Lopes, Susana M., Jost, Carolina R., Wijnholds, Jan
Published in Stem cell reports (14.05.2019)
Published in Stem cell reports (14.05.2019)
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Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1
Boon, Nanda, Alves, C Henrique, Mulder, Aat A, Andriessen, Charlotte A, Buck, Thilo M, Quinn, Peter M J, Vos, Rogier M, Koster, Abraham J, Jost, Carolina R, Wijnholds, Jan
Published in International journal of molecular sciences (30.03.2021)
Published in International journal of molecular sciences (30.03.2021)
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Postmortem MRI and histology demonstrate differential iron accumulation and cortical myelin organization in early- and late-onset Alzheimer's disease
Bulk, Marjolein, Abdelmoula, Walid M., Nabuurs, Rob J.A., van der Graaf, Linda M., Mulders, Coen W.H., Mulder, Aat A., Jost, Carolina R., Koster, Abraham J., van Buchem, Mark A., Natté, Remco, Dijkstra, Jouke, van der Weerd, Louise
Published in Neurobiology of aging (01.02.2018)
Published in Neurobiology of aging (01.02.2018)
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NOTCH3 variant position is associated with NOTCH3 aggregation load in CADASIL vasculature
Gravesteijn, Gido, Hack, Remco J., Mulder, Aat A., Cerfontaine, Minne N., Doorn, Remco, Hegeman, Ingrid M., Jost, Carolina R., Rutten, Julie W., Lesnik Oberstein, Saskia A. J.
Published in Neuropathology and applied neurobiology (01.02.2022)
Published in Neuropathology and applied neurobiology (01.02.2022)
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Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype
Quinn, Peter M, Mulder, Aat A, Henrique Alves, C, Desrosiers, Mélissa, de Vries, Sharon I, Klooster, Jan, Dalkara, Deniz, Koster, Abraham J, Jost, Carolina R, Wijnholds, Jan
Published in Human molecular genetics (01.01.2019)
Published in Human molecular genetics (01.01.2019)
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In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells
van Riet, Sander, Ninaber, Dennis K., Mikkers, Harald M. M., Tetley, Teresa D., Jost, Carolina R., Mulder, Aat A., Pasman, Thijs, Baptista, Danielle, Poot, André A., Truckenmüller, Roman, Mummery, Christine L., Freund, Christian, Rottier, Robbert J., Hiemstra, Pieter S.
Published in Scientific reports (26.03.2020)
Published in Scientific reports (26.03.2020)
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In vivo monitoring of mRNA movement in Drosophila body wall muscle cells reveals the presence of myofiber domains
van Gemert, Alice M C, van der Laan, Annelies M A, Pilgram, Gonneke S K, Fradkin, Lee G, Noordermeer, Jasprina N, Tanke, Hans J, Jost, Carolina R
Published in PloS one (17.08.2009)
Published in PloS one (17.08.2009)
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Naturally occurring NOTCH3 exon skipping attenuates NOTCH3 protein aggregation and disease severity in CADASIL patients
Gravesteijn, Gido, Dauwerse, Johannes G, Overzier, Maurice, Brouwer, Gwendolyn, Hegeman, Ingrid, Mulder, Aat A, Baas, Frank, Kruit, Mark C, Terwindt, Gisela M, van Duinen, Sjoerd G, Jost, Carolina R, Aartsma-Rus, Annemieke, Lesnik Oberstein, Saskia A J, Rutten, Julie W
Published in Human molecular genetics (21.07.2020)
Published in Human molecular genetics (21.07.2020)
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Bi-allelic NIT1 variants cause a brain small vessel disease characterized by movement disorders, massively dilated perivascular spaces, and intracerebral hemorrhage
Rutten, Julie W., Cerfontaine, Minne N., Dijkstra, Kyra L., Mulder, Aat A., Vreijling, Jeroen, Kruit, Mark, Koning, Roman I., de Bot, Susanne T., van Nieuwenhuizen, Koen M., Baelde, Hans J., Berendse, Henk W., Mei, Leon H., Ruijter, George J.G., Baas, Frank, Jost, Carolina R., van Duinen, Sjoerd G., Nibbeling, Esther A.R., Gravesteijn, Gido, Lesnik Oberstein, Saskia A.J.
Published in Genetics in medicine (01.06.2024)
Published in Genetics in medicine (01.06.2024)
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High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II
van Hoolwerff, Marcella, Rodríguez Ruiz, Alejandro, Bouma, Marga, Suchiman, H Eka D, Koning, Roman I, Jost, Carolina R, Mulder, Aat A, Freund, Christian, Guilak, Farshid, Ramos, Yolande F M, Meulenbelt, Ingrid
Published in Science advances (05.11.2021)
Published in Science advances (05.11.2021)
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CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids
Buck, Thilo M., Quinn, Peter M.J., Pellissier, Lucie P., Mulder, Aat A., Jongejan, Aldo, Lu, Xuefei, Boon, Nanda, Koot, Daniëlle, Almushattat, Hind, Arendzen, Christiaan H., Vos, Rogier M., Bradley, Edward J., Freund, Christian, Mikkers, Harald M.M., Boon, Camiel J.F., Moerland, Perry D., Baas, Frank, Koster, Abraham J., Neefjes, Jacques, Berlin, Ilana, Jost, Carolina R., Wijnholds, Jan
Published in Stem cell reports (12.09.2023)
Published in Stem cell reports (12.09.2023)
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NOTCH3 VARIANT POSITION IS ASSOCIATED WITH VASCULAR NOTCH3 AGGREGATION LOAD IN CADASIL PATIENTS
Gravesteijn, Gido, Hack, Remco J., Mulder, Aat A., Cerfontaine, Minne N., van Doorn, Remco, Hegeman, Ingrid M., Jost, Carolina R., Rutten, Julie W., Oberstein, Saskia A.J. Lesnik
Published in Cerebral circulation - cognition and behavior (2024)
Published in Cerebral circulation - cognition and behavior (2024)
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Progression and Classification of Granular Osmiophilic Material (GOM) Deposits in Functionally Characterized Human NOTCH3 Transgenic Mice
Gravesteijn, Gido, Munting, Leon P., Overzier, Maurice, Mulder, Aat A., Hegeman, Ingrid, Derieppe, Marc, Koster, Abraham J., van Duinen, Sjoerd G., Meijer, Onno C., Aartsma-Rus, Annemieke, van der Weerd, Louise, Jost, Carolina R., van den Maagdenberg, Arn M. J. M., Rutten, Julie W., Lesnik Oberstein, Saskia A. J.
Published in Translational stroke research (01.06.2020)
Published in Translational stroke research (01.06.2020)
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Using an Extracurricular Honors Program to Engage Future Physicians Into Scientific Research in Early Stages of Medical Training
Ommering, Belinda W. C., van den Elsen, Peter J., van der Zee, Jolanda, Jost, Carolina R., Dekker, Friedo W.
Published in Medical science educator (2018)
Published in Medical science educator (2018)
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Structural and behavioural consequences of double deficiency for creatine kinases BCK and UbCKmit
Streijger, Femke, Oerlemans, Frank, Ellenbroek, Bart A., Jost, Carolina R., Wieringa, Bé, Van der Zee, Catharina E.E.M.
Published in Behavioural brain research (28.02.2005)
Published in Behavioural brain research (28.02.2005)
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Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility
Jost, Carolina R., Van der Zee, Catharina E. E. M., In 't Zandt, Henricus J. A., Oerlemans, Frank, Verheij, Michel, Streijger, Femke, Fransen, Jack, Heerschap, Arend, Cools, Alexander R., Wieringa, Bé
Published in The European journal of neuroscience (01.05.2002)
Published in The European journal of neuroscience (01.05.2002)
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