Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation
Wong, Joyce J W, Young, Tracy A, Zhang, Jiayan, Liu, Shiheng, Leser, George P, Komives, Elizabeth A, Lamb, Robert A, Zhou, Z Hong, Salafsky, Joshua, Jardetzky, Theodore S
Published in Nature communications (03.10.2017)
Published in Nature communications (03.10.2017)
Get full text
Journal Article
ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis
Ma, Bin, Marcotte, Doug, Paramasivam, Murugan, Michelsen, Klaus, Wang, Ti, Bertolotti-Ciarlet, Andrea, Jones, John Howard, Moree, Ben, Butko, Margaret, Salafsky, Joshua, Sun, Xin, McKee, Timothy, Silvian, Laura F
Published in PloS one (10.11.2016)
Published in PloS one (10.11.2016)
Get full text
Journal Article
Second-Harmonic Generation (SHG) for Conformational Measurements: Assay Development, Optimization, and Screening
Young, Tracy A, Moree, Ben, Butko, Margaret T, Clancy, Bason, Geck Do, Mary, Gheyi, Tarun, Strelow, John, Carrillo, Juan J, Salafsky, Joshua
Published in Methods in enzymology (2018)
Published in Methods in enzymology (2018)
Get more information
Journal Article
Identification of inactive conformation‐selective interleukin‐2‐inducible T‐cell kinase (ITK) inhibitors based on second‐harmonic generation
Hantani, Yoshiji, Iio, Kiyosei, Hantani, Rie, Umetani, Kayo, Sato, Toshihiro, Young, Tracy, Connell, Katelyn, Kintz, Sam, Salafsky, Joshua
Published in FEBS open bio (01.09.2018)
Published in FEBS open bio (01.09.2018)
Get full text
Journal Article
Second-harmonic phase determination by real-time in situ interferometry
Clancy, Bason, Salafsky, Joshua
Published in Physical chemistry chemical physics : PCCP (01.02.2017)
Published in Physical chemistry chemical physics : PCCP (01.02.2017)
Get full text
Journal Article
Ligand-induced conformational changes in protein molecules detected by sum-frequency generation
Salafsky, Joshua, Johansson, Patrik K., Abdelkader, Elwy, Otting, Gottfried
Published in Biophysical journal (19.09.2024)
Published in Biophysical journal (19.09.2024)
Get full text
Journal Article
Modeling Conformational Changes in Proteins Based on Second Harmonic Generation Data
Axen, Seth D., Clancy, Bason, Salafsky, Joshua, Sali, Andrej
Published in Biophysical journal (15.02.2019)
Published in Biophysical journal (15.02.2019)
Get full text
Journal Article
Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy
Spangler, Jamie B, Trotta, Eleonora, Tomala, Jakub, Peck, Ariana, Young, Tracy A, Savvides, Christina S, Silveria, Stephanie, Votavova, Petra, Salafsky, Joshua, Pande, Vijay S, Kovar, Marek, Bluestone, Jeffrey A, Garcia, K Christopher
Published in The Journal of immunology (1950) (01.10.2018)
Published in The Journal of immunology (1950) (01.10.2018)
Get full text
Journal Article
Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric α-Synuclein and Reduce Its Aggregation in Cells
Moree, Ben, Yin, Guowei, Lázaro, Diana F., Munari, Francesca, Strohäker, Timo, Giller, Karin, Becker, Stefan, Outeiro, Tiago F., Zweckstetter, Markus, Salafsky, Joshua
Published in The Journal of biological chemistry (13.11.2015)
Published in The Journal of biological chemistry (13.11.2015)
Get full text
Journal Article
Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors
Spagnuolo, Lauren A, Eltschkner, Sandra, Yu, Weixuan, Daryaee, Fereidoon, Davoodi, Shabnam, Knudson, Susan E, Allen, Eleanor K. H, Merino, Jonathan, Pschibul, Annica, Moree, Ben, Thivalapill, Neil, Truglio, James J, Salafsky, Joshua, Slayden, Richard A, Kisker, Caroline, Tonge, Peter J
Published in Journal of the American Chemical Society (08.03.2017)
Published in Journal of the American Chemical Society (08.03.2017)
Get full text
Journal Article
Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder
Donohue, Elizabeth, Khorsand, Sina, Mercado, Gabriel, Varney, Kristen M., Wilder, Paul T., Yu, Wenbo, MacKerell, Alexander D., Alexander, Patrick, Van, Que N., Moree, Ben, Stephen, Andrew G., Weber, David J., Salafsky, Joshua, McCormick, Frank
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2019)
Get full text
Journal Article
Abstract 4018: Identifying allosteric modulators of KRas using second harmonic generation
Vo, Elizabeth Donohue, Mercado, Gabriel Besserer, Alexander, Patrick, Moree, Ben, Van, Que, Stephen, Andrew G., Salafsky, Joshua, McCormick, Frank
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article