Ovarian Cancer-associated Mutations Disable Catalytic Activity of CDK12, a Kinase That Promotes Homologous Recombination Repair and Resistance to Cisplatin and Poly(ADP-ribose) Polymerase Inhibitors
Joshi, Poorval M., Sutor, Shari L., Huntoon, Catherine J., Karnitz, Larry M.
Published in The Journal of biological chemistry (28.03.2014)
Published in The Journal of biological chemistry (28.03.2014)
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Journal Article
SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells
Liang, Yang, Tebaldi, Toma, Rejeski, Kai, Joshi, Poorval, Stefani, Giovanni, Taylor, Ashley, Song, Yuanbin, Vasic, Radovan, Maziarz, Jamie, Balasubramanian, Kunthavai, Ardasheva, Anastasia, Ding, Alicia, Quattrone, Alessandro, Halene, Stephanie
Published in Leukemia (01.12.2018)
Published in Leukemia (01.12.2018)
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Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination
Huehls, Amelia M, Huntoon, Catherine J, Joshi, Poorval M, Baehr, Carly A, Wagner, Jill M, Wang, Xiaoxiao, Lee, Marietta Y, Karnitz, Larry M
Published in Molecular pharmacology (01.01.2016)
Published in Molecular pharmacology (01.01.2016)
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Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq
Biancon, Giulia, Busarello, Emma, Joshi, Poorval, Lesch, Bluma J., Halene, Stephanie, Tebaldi, Toma
Published in STAR protocols (16.12.2022)
Published in STAR protocols (16.12.2022)
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Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies
Biancon, Giulia, Joshi, Poorval, Zimmer, Joshua T., Hunck, Torben, Gao, Yimeng, Lessard, Mark D., Courchaine, Edward, Barentine, Andrew E.S., Machyna, Martin, Botti, Valentina, Qin, Ashley, Gbyli, Rana, Patel, Amisha, Song, Yuanbin, Kiefer, Lea, Viero, Gabriella, Neuenkirchen, Nils, Lin, Haifan, Bewersdorf, Joerg, Simon, Matthew D., Neugebauer, Karla M., Tebaldi, Toma, Halene, Stephanie
Published in Molecular cell (17.03.2022)
Published in Molecular cell (17.03.2022)
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Incorporation of the Kaposi’s sarcoma-associated herpesvirus capsid vertex-specific component (CVSC) into self-assembled capsids
Grzesik, Peter, MacMath, Derek, Henson, Brandon, Prasad, Sanjana, Joshi, Poorval, Desai, Prashant J.
Published in Virus research (15.05.2017)
Published in Virus research (15.05.2017)
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Visualization of herpes simplex virus type 1 virions using fluorescent colors
Etienne, Lyns, Joshi, Poorval, Dingle, Laura, Huang, Eugene, Grzesik, Peter, Desai, Prashant J.
Published in Journal of virological methods (01.03.2017)
Published in Journal of virological methods (01.03.2017)
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Journal Article
U2AF1 Mutations Enhance Stress Granule Response in Myeloid Malignancies
Biancon, Giulia, Joshi, Poorval, Zimmer, Joshua T, Hunck, Torben, Gao, Yimeng, Lessard, Mark D, Courchaine, Edward, Barentine, Andrew ES, Machyna, Martin, Botti, Valentina, Qin, Ashley, Gbyli, Rana, Patel, Amisha, Song, Yuanbin, Kiefer, Lea, Viero, Gabriella, Neuenkirchen, Nils, Lin, Haifan, Bewersdorf, Joerg, Simon, Matthew D, Neugebauer, Karla M, Tebaldi, Toma, Halene, Stephanie
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Mettl3 Mediated m6A Modification Is Essential in Fetal Hematopoiesis
Gao, Yimeng, Vasic, Radovan, Tebaldi, Toma, Song, Yuanbin, Teng, Rhea, Joshi, Poorval, Viero, Gabriella, Xiao, Andrew, Batista, Pedro, Li, Huabing, Flavell, Richard, Halene, Stephanie
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
High-Resolution Binding Atlas of U2AF1 Mutants Uncovers New Complexity in Splicing Alterations and Kinetics in Myeloid Malignancies
Biancon, Giulia, Joshi, Poorval, Hunck, Torben, Zimmer, Josh, Gao, Yimeng, Machyna, Martin, Botti, Valentina, Qin, Ashley, Viero, Gabriella, Neuenkirchen, Nils, Taylor, Ashley, Gbyli, Rana, Patel, Amisha, Ardasheva, Anastasia, Fu, Xiaoying, Lin, Haifan, Simon, Matthew D, Neugebauer, Karla M, Tebaldi, Toma, Halene, Stephanie
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
Gao, Yimeng, Vasic, Radovan, Song, Yuanbin, Teng, Rhea, Liu, Chengyang, Gbyli, Rana, Biancon, Giulia, Nelakanti, Raman, Lobben, Kirsten, Kudo, Eriko, Liu, Wei, Ardasheva, Anastasia, Fu, Xiaoying, Wang, Xiaman, Joshi, Poorval, Lee, Veronica, Dura, Burak, Viero, Gabriella, Iwasaki, Akiko, Fan, Rong, Xiao, Andrew, Flavell, Richard A., Li, Hua-Bing, Tebaldi, Toma, Halene, Stephanie
Published in Immunity (Cambridge, Mass.) (16.06.2020)
Published in Immunity (Cambridge, Mass.) (16.06.2020)
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Journal Article
m 6 A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
Gao, Yimeng, Vasic, Radovan, Song, Yuanbin, Teng, Rhea, Liu, Chengyang, Gbyli, Rana, Biancon, Giulia, Nelakanti, Raman, Lobben, Kirsten, Kudo, Eriko, Liu, Wei, Ardasheva, Anastasia, Fu, Xiaoying, Wang, Xiaman, Joshi, Poorval, Lee, Veronica, Dura, Burak, Viero, Gabriella, Iwasaki, Akiko, Fan, Rong, Xiao, Andrew, Flavell, Richard A, Li, Hua-Bing, Tebaldi, Toma, Halene, Stephanie
Published in Immunity (Cambridge, Mass.) (16.06.2020)
Published in Immunity (Cambridge, Mass.) (16.06.2020)
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Journal Article
Abstract POSTER-BIOL-1325: Ovarian cancer-associated CDK12 mutations disable its kinase activity and cause defects in homologous recombination
Joshi, Poorval M., Sutor, Shari L., Huntoon, Catherine J., Karnitz, Larry M.
Published in Clinical cancer research (15.08.2015)
Published in Clinical cancer research (15.08.2015)
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Journal Article
U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA Complex
Biancon, Giulia, Joshi, Poorval, Hunck, Torben, Gao, Yimeng, Botti, Valentina, Qin, Ashley, Sadykov, Mukhtar, Wang, Xiaman, Viero, Gabriella, Neuenkirchen, Nils, Taylor, Ashley, Huang, Jane, Ardasheva, Anastasia, Fu, Xiaoying, Lin, Haifan, Pillai, Manoj M, Kielkopf, Clara L, Neugebauer, Karla M, Tebaldi, Toma, Halene, Stephanie
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure
Gao, Yimeng, Vasic, Radovan, Song, Yuanbin, Teng, Rhea, Gbyli, Rana, Biancon, Giulia, Nelakanti, Raman, Kudo, Eriko, Liu, Wei, Ardasheva, Anastasia, Fu, Xiaoying, Wang, Xiaman, Joshi, Poorval, Dura, Burak, Lee, Veronica, Viero, Gabriella, Iwasaki, Akiko, Fan, Rong, Xiao, Andrew, Flavell, Richard, Li, Hua-Bing, Tebaldi, Toma, Halene, Stephanie
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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