Drug safety is a barrier to the discovery and development of new androgen receptor antagonists
Foster, William R., Car, Bruce D., Shi, Hong, Levesque, Paul C., Obermeier, Mary T., Gan, Jinping, Arezzo, Joseph C., Powlin, Stephanie S., Dinchuk, Joseph E., Balog, Aaron, Salvati, Mark E., Attar, Ricardo M., Gottardis, Marco M.
Published in The Prostate (01.04.2011)
Published in The Prostate (01.04.2011)
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Journal Article
P2Y6 receptor potentiates pro-inflammatory responses in macrophages and exhibits differential roles in atherosclerotic lesion development
Garcia, Ricardo A, Yan, Mujing, Search, Debra, Zhang, Rongan, Carson, Nancy L, Ryan, Carol S, Smith-Monroy, Constance, Zheng, Joanna, Chen, Jian, Kong, Yan, Tang, Huaping, Hellings, Samuel E, Wardwell-Swanson, Judith, Dinchuk, Joseph E, Psaltis, George C, Gordon, David A, Glunz, Peter W, Gargalovic, Peter S
Published in PloS one (31.10.2014)
Published in PloS one (31.10.2014)
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Journal Article
Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction
Kim, Sean, Dinchuk, Joseph E, Anthony, Monique N, Orcutt, Tami, Zoeckler, Mary E, Sauer, Mary B, Mosure, Kathleen W, Vuppugalla, Ragini, Grace, Jr, James E, Simmermacher, Jean, Dulac, Heidi A, Pizzano, Jennifer, Sinz, Michael
Published in Drug metabolism and disposition (01.01.2010)
Published in Drug metabolism and disposition (01.01.2010)
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Journal Article
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
Dinchuk, Joseph E, Car, Bruce D, Focht, Richard J, Johnston, Jennifer J, Jaffee, Bruce D, Covington, Maryanne B, Contel, Nancy R, Eng, Vicki M, Collins, Robert J, Czerniak, Philip M, Gorry, Stewart A, Trzaskos, James M
Published in Nature (London) (23.11.1995)
Published in Nature (London) (23.11.1995)
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Journal Article
Multiple Female Reproductive Failures in Cyclooxygenase 2–Deficient Mice
Lim, Hyunjung, Paria, Bibhash C, Das, Sanjoy K, Dinchuk, Joseph E, Langenbach, Robert, Trzaskos, James M, Dey, Sudhansu K
Published in Cell (17.10.1997)
Published in Cell (17.10.1997)
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Journal Article
Insulin Receptor (IR) Pathway Hyperactivity in IGF-IR Null Cells and Suppression of Downstream Growth Signaling Using the Dual IGF-IR/IR Inhibitor, BMS-754807
Dinchuk, Joseph E, Cao, Carolyn, Huang, Fei, Reeves, Karen A, Wang, Jeanne, Myers, Fanny, Cantor, Glenn H, Zhou, Xiadi, Attar, Ricardo M, Gottardis, Marco, Carboni, Joan M
Published in Endocrinology (Philadelphia) (01.09.2010)
Published in Endocrinology (Philadelphia) (01.09.2010)
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Journal Article
COX-3: in the wrong frame in mind
Dinchuk, Joseph E., Liu, Richard Q., Trzaskos, James M.
Published in Immunology letters (03.03.2003)
Published in Immunology letters (03.03.2003)
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Journal Article
Absence of Post-translational Aspartyl β-Hydroxylation of Epidermal Growth Factor Domains in Mice Leads to Developmental Defects and an Increased Incidence of Intestinal Neoplasia
Dinchuk, Joseph E., Focht, Richard J., Kelley, Jennifer A., Henderson, Nancy L., Zolotarjova, Nina I., Wynn, Richard, Neff, Nicola T., Link, John, Huber, Reid M., Burn, Timothy C., Rupar, Mark J., Cunningham, Mark R., Selling, Bernard H., Ma, Jianhong, Stern, Andrew A., Hollis, Gregory F., Stein, Robert B., Friedman, Paul A.
Published in The Journal of biological chemistry (12.04.2002)
Published in The Journal of biological chemistry (12.04.2002)
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Journal Article
Antisense oligonucleotides selectively regulate aspartyl beta-hydroxylase and its truncated protein isoform in vitro but distribute poorly into A549 tumors in vivo
Ho, Siew Peng, Scully, Michael S, Krauthauser, Candice M, Wexler, Eric J, Stow, Mark D, Dinchuk, Joseph E, Kerr, Janet S, Friedman, Paul A
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
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Journal Article
Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
Oshima, Masanobu, Dinchuk, Joseph E, Kargman, Stacia L, Oshima, Hiroko, Hancock, Bruno, Kwong, Elizabeth, Trzaskos, James M, Evans, Jilly F, Taketo, Makoto M
Published in Cell (01.11.1996)
Published in Cell (01.11.1996)
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Journal Article
P2Y.sub.6 Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development
Garcia, Ricardo A, Yan, Mujing, Search, Debra, Zhang, Rongan, Carson, Nancy L, Ryan, Carol S, Smith-Monroy, Constance, Zheng, Joanna, Chen, Jian, Kong, Yan, Tang, Huaping, Hellings, Samuel E, Wardwell-Swanson, Judith, Dinchuk, Joseph E, Psaltis, George C, Gordon, David A, Glunz, Peter W, Gargalovic, Peter S
Published in PloS one (31.10.2014)
Published in PloS one (31.10.2014)
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Journal Article
Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Inductions
KIM, Sean, DINCHUK, Joseph E, DULAC, Heidi A, PIZZANO, Jennifer, SINZ, Michael, ANTHONY, Monique N, ORCUTT, Tami, ZOECKLER, Mary E, SAUER, Mary B, MOSURE, Kathleen W, VUPPUGALLA, Ragini, GRACE, James E, SIMMERMACHER, Jean
Published in Drug metabolism and disposition (2010)
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Published in Drug metabolism and disposition (2010)
Journal Article
Aspartyl β-Hydroxylase (Asph) and an Evolutionarily Conserved Isoform of Asph Missing the Catalytic Domain Share Exons with Junctin
Dinchuk, Joseph E., Henderson, Nancy L., Burn, Timothy C., Huber, Reid, Ho, Siew Peng, Link, John, O'Neil, Karyn T, Focht, Richard J., Scully, Michael S., Hollis, Jeannine M., Hollis, Gregory F., Friedman, Paul A.
Published in The Journal of biological chemistry (15.12.2000)
Published in The Journal of biological chemistry (15.12.2000)
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Journal Article
Cyclooxygenase-2 is essential for normal recovery from 5-fluorouracil–induced myelotoxicity in mice
Lorenz, Meike, Slaughter, Helen S., Wescott, Debra M., Carter, Sherryann I., Schnyder, Bruno, Dinchuk, Joseph E., Car, Bruce D.
Published in Experimental hematology (01.10.1999)
Published in Experimental hematology (01.10.1999)
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Journal Article
Antisense Oligonucleotides Selectively Regulate Aspartyl β-Hydroxylase and Its Truncated Protein Isoform in Vitro but Distribute Poorly into A549 Tumors in Vivo
Siew Peng Ho, Michael S. Scully, Candice M. Krauthauser, Eric J. Wexler, Mark D. Stow, Joseph E. Dinchuk, Janet S. Kerr, Paul A. Friedman
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
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Journal Article
Absence of Post-translational Aspartyl β-Hydroxylation of Epidermal Growth Factor Domains in Mice Leads to Developmental Defects and an Increased Incidence of Intestinal Neoplasia
Joseph E. Dinchuk, Richard J. Focht, Jennifer A. Kelley, Nancy L. Henderson, Nina I. Zolotarjova, Richard Wynn, Nicola T. Neff, John Link, Reid M. Huber, Timothy C. Burn, Mark J. Rupar, Mark R. Cunningham, Bernard H. Selling, Jianhong Ma, Andrew A. Stern, Gregory F. Hollis, Robert B. Stein, Paul A. Friedman
Published in The Journal of biological chemistry (12.04.2002)
Published in The Journal of biological chemistry (12.04.2002)
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Journal Article
Aspartyl β-Hydroxylase (Asph) and an Evolutionarily Conserved Isoform of Asph Missing the Catalytic Domain Share Exons with Junctin
Joseph E. Dinchuk, Nancy L. Henderson, Timothy C. Burn, Reid Huber, Siew Peng Ho, John Link, Karyn T O'Neil, Richard J. Focht, Michael S. Scully, Jeannine M. Hollis, Gregory F. Hollis, Paul A. Friedman
Published in The Journal of biological chemistry (15.12.2000)
Published in The Journal of biological chemistry (15.12.2000)
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Journal Article
CHIMÄRE CHEMOKINREZEPTORPOLYPEPTIDE
SCHERLE, PEGGY ANN, ZHAO, QIHONG, DINCHUK, JOSEPH E, CARTER, PERCY, DAVIES, PAUL, SOLOMON, KIMBERLY
Year of Publication 15.01.2012
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Year of Publication 15.01.2012
Patent
Chimeric chemokine receptor polypeptides
CARTER, PERCY, H, SCHERLE, PEGGY ANN, ZHAO, QIHONG, DINCHUK, JOSEPH E, DAVIES, PAUL, SOLOMON, KIMBERLY, A
Year of Publication 21.12.2011
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Year of Publication 21.12.2011
Patent