Copper Binding by Tetrathiomolybdate Attenuates Angiogenesis and Tumor Cell Proliferation through the Inhibition of Superoxide Dismutase 1
Jose C. Juarez, Oscar Betancourt, Jr, Steven R. Pirie-Shepherd, Xiaojun Guan, Melissa L. Price, David E. Shaw, Andrew P. Mazar, Fernando Doñate
Published in Clinical cancer research (15.08.2006)
Published in Clinical cancer research (15.08.2006)
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Peptides derived from the histidine-proline domain of the histidine-proline-rich glycoprotein bind to tropomyosin and have antiangiogenic and antitumor activities
DONATE, Fernando, JUAREZ, Jose C, XIAOJUN GUAN, SHIPULINA, Natalya V, PLUNKETT, Marian L, TEL-TSUR, Ziva, SHAW, David E, MORGAN, William T, MAZAR, Andrew P
Published in Cancer research (Chicago, Ill.) (15.08.2004)
Published in Cancer research (Chicago, Ill.) (15.08.2004)
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Histidine-proline rich glycoprotein (HPRG) binds and transduces anti-angiogenic signals through cell surface tropomyosin on endothelial cells
Guan, Xiaojun, Juarez, Jose C, Qi, Xiaoping, Shipulina, Natalya V, Shaw, David E, Morgan, William T, McCrae, Keith R, Mazar, Andrew P, Doñate, Fernando
Published in Thrombosis and haemostasis (01.08.2004)
Published in Thrombosis and haemostasis (01.08.2004)
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The Antiangiogenic Activity of Cleaved High Molecular Weight Kininogen Is Mediated through Binding to Endothelial Cell Tropomyosin
Zhang, Jing-Chuan, Doñate, Fernando, Qi, Xiaoping, Ziats, Nicholas P., Juarez, Jose C., Mazar, Andrew P., Pang, Yuan-Ping, McCrae, Keith R.
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2002)
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Journal Article
Superoxide Dismutase 1 (SOD1) Is Essential for H₂O₂-Mediated Oxidation and Inactivation of Phosphatases in Growth Factor Signaling
Juarez, Jose C., Manuia, Mari, Burnett, Mark E., Betancourt, Oscar, Boivin, Benoit, Shaw, David E., Tonks, Nicholas K., Mazar, Andrew P., Doñate, Fernando
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
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Journal Article
Histidine-proline-rich glycoprotein has potent antiangiogenic activity mediated through the histidine-proline-rich domain
JUAREZ, Jose C, XIAOJUN GUAN, MORGAN, William T, DONATE, Fernando, SHIPULINA, Natalya V, PLUNKETT, Marian L, PARRY, Graham C, SHAW, David Elliot, ZHANG, Jing-Chuan, RABBANI, Shafaat A, MCCRAE, Keith R, MAZAR, Andrew P
Published in Cancer research (Chicago, Ill.) (15.09.2002)
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Published in Cancer research (Chicago, Ill.) (15.09.2002)
Journal Article
Synthesis and Evaluation of Multisubstrate Bicyclic Pyrimidine Nucleoside Inhibitors of Human Thymidine Phosphorylase
Allan, Amy L, Gladstone, Patricia L, Price, Melissa L. P, Hopkins, Stephanie A, Juarez, Jose C, Doñate, Fernando, Ternansky, Robert J, Shaw, David E, Ganem, Bruce, Li, Yingbo, Wang, Weiru, Ealick, Steven
Published in Journal of medicinal chemistry (28.12.2006)
Published in Journal of medicinal chemistry (28.12.2006)
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Design of novel N-(2,4-dioxo-1,2,3,4-tetrahydro-thieno[3,2- d]pyrimidin-7-yl)-guanidines as thymidine phosphorylase inhibitors, and flexible docking to a homology model
Price, MelissaL.P., Guida, WayneC, Jackson, TaraE, Nydick, JasonA, Gladstone, PatriciaL, Juarez, JoséC., Doñate, Fernando, Ternansky, RobertJ
Published in Bioorganic & medicinal chemistry letters (06.01.2003)
Published in Bioorganic & medicinal chemistry letters (06.01.2003)
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Superoxide dismutase 1 (SOD1) is essential for H^sub 2^O^sub 2^-mediated oxidation and inactivation of phosphatases in growth factor signaling
Juarez, Jose C, Manuia, Mari, Burnett, Mark E, Betancourt, Oscar, Boivin, Benoit, Shaw, David E, Tonks, Nicholas K, Mazar, Andrew P, Doñate, Fernando
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
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Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
Journal Article
Superoxide dismutase 1 (SOD1) is essential for H 2 O 2 -mediated oxidation and inactivation of phosphatases in growth factor signaling
Juarez, Jose C., Manuia, Mari, Burnett, Mark E., Betancourt, Oscar, Boivin, Benoit, Shaw, David E., Tonks, Nicholas K., Mazar, Andrew P., Doñate, Fernando
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
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Journal Article
Superoxide dismutase 1 (SOD1) is essential for H sub(2)O sub(2)-mediated oxidation and inactivation of phosphatases in growth factor signaling
Juarez, Jose C, Manuia, Mari, Burnett, Mark E, Betancourt, Oscar, Boivin, Benoit, Shaw, David E, Tonks, Nicholas K, Mazar, Andrew P, Donate, Fernando
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2008)
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Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2008)
Journal Article
Design of Novel N-(2,4-Dioxo-1,2,3,4-tetrahydro-thieno[3,2-d]pyrimidin-7-yl)-guanidines [cf. (VII), (XI)] as Thymidine Phosphorylase Inhibitors, and Flexible Docking to a Homology Model
Price, Melissa L. P., Guida, Wayne C., Jackson, Tara E., Nydick, Jason A., Gladstone, Patricia L., Juarez, Jose C., Donate, Fernando, Ternansky, Robert J.
Published in ChemInform (10.06.2003)
Published in ChemInform (10.06.2003)
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