A Mitochondria-Associated Oxidative Stress Perspective on Huntington's Disease
Zheng, Ju, Winderickx, Joris, Franssens, Vanessa, Liu, Beidong
Published in Frontiers in molecular neuroscience (19.09.2018)
Published in Frontiers in molecular neuroscience (19.09.2018)
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Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase
Dechant, Reinhard, Binda, Matteo, Lee, Sung Sik, Pelet, Serge, Winderickx, Joris, Peter, Matthias
Published in The EMBO journal (04.08.2010)
Published in The EMBO journal (04.08.2010)
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Journal Article
Digital ELISA for the quantification of attomolar concentrations of Alzheimer's disease biomarker protein Tau in biological samples
Pérez-Ruiz, Elena, Decrop, Deborah, Ven, Karen, Tripodi, Lisa, Leirs, Karen, Rosseels, Joelle, van de Wouwer, Marlies, Geukens, Nick, De Vos, Ann, Vanmechelen, Eugeen, Winderickx, Joris, Lammertyn, Jeroen, Spasic, Dragana
Published in Analytica chimica acta (26.07.2018)
Published in Analytica chimica acta (26.07.2018)
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Journal Article
The TORC1-Sch9 pathway as a crucial mediator of chronological lifespan in the yeast Saccharomyces cerevisiae
Deprez, Marie-Anne, Eskes, Elja, Winderickx, Joris, Wilms, Tobias
Published in FEMS yeast research (01.08.2018)
Published in FEMS yeast research (01.08.2018)
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Journal Article
Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation
Caligaris, Marco, Nicastro, Raffaele, Hu, Zehan, Tripodi, Farida, Hummel, Johannes Erwin, Pillet, Benjamin, Deprez, Marie-Anne, Winderickx, Joris, Rospert, Sabine, Coccetti, Paola, Dengjel, Jörn, De Virgilio, Claudio
Published in eLife (07.02.2023)
Published in eLife (07.02.2023)
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Inter-organellar Communication in Parkinson's and Alzheimer's Disease: Looking Beyond Endoplasmic Reticulum-Mitochondria Contact Sites
Vrijsen, Stephanie, Vrancx, Céline, Del Vecchio, Mara, Swinnen, Johannes V, Agostinis, Patrizia, Winderickx, Joris, Vangheluwe, Peter, Annaert, Wim
Published in Frontiers in neuroscience (21.06.2022)
Published in Frontiers in neuroscience (21.06.2022)
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Journal Article
The nutrient-responsive CDK Pho85 primes the Sch9 kinase for its activation by TORC1
Deprez, Marie-Anne, Caligaris, Marco, Rosseels, Joëlle, Hatakeyama, Riko, Ghillebert, Ruben, Sampaio-Marques, Belém, Mudholkar, Kaivalya, Eskes, Elja, Meert, Els, Ungermann, Christian, Ludovico, Paula, Rospert, Sabine, De Virgilio, Claudio, Winderickx, Joris
Published in PLoS genetics (15.02.2023)
Published in PLoS genetics (15.02.2023)
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Lsm7 phase-separated condensates trigger stress granule formation
Lindström, Michelle, Chen, Lihua, Jiang, Shan, Zhang, Dan, Gao, Yuan, Zheng, Ju, Hao, Xinxin, Yang, Xiaoxue, Kabbinale, Arpitha, Thoma, Johannes, Metzger, Lisa C., Zhang, Deyuan Y., Zhu, Xuefeng, Liu, Huisheng, Gustafsson, Claes M., Burmann, Björn M., Winderickx, Joris, Sunnerhagen, Per, Liu, Beidong
Published in Nature communications (28.06.2022)
Published in Nature communications (28.06.2022)
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Journal Article
Yeasts as Complementary Model Systems for the Study of the Pathological Repercussions of Enhanced Synphilin-1 Glycation and Oxidation
Seynnaeve, David, Mulvihill, Daniel P, Winderickx, Joris, Franssens, Vanessa
Published in International journal of molecular sciences (07.02.2021)
Published in International journal of molecular sciences (07.02.2021)
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Journal Article
The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability
Wilms, Tobias, Swinnen, Erwin, Eskes, Elja, Dolz-Edo, Laura, Uwineza, Alice, Van Essche, Ruben, Rosseels, Joëlle, Zabrocki, Piotr, Cameroni, Elisabetta, Franssens, Vanessa, De Virgilio, Claudio, Smits, Gertien J, Winderickx, Joris
Published in PLoS genetics (12.06.2017)
Published in PLoS genetics (12.06.2017)
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SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy
Sampaio-Marques, Belém, Felgueiras, Carolina, Silva, Alexandra, Rodrigues, Márcio, Tenreiro, Sandra, Franssens, Vanessa, Reichert, Andreas S, Outeiro, Tiago F, Winderickx, Joris, Ludovico, Paula
Published in Autophagy (01.10.2012)
Published in Autophagy (01.10.2012)
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Journal Article
Trehalose-6-phosphate synthesis controls yeast gluconeogenesis downstream and independent of SNF1
Deroover, Sofie, Ghillebert, Ruben, Broeckx, Tom, Winderickx, Joris, Rolland, Filip
Published in FEMS yeast research (01.06.2016)
Published in FEMS yeast research (01.06.2016)
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Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
Dujardin, Simon, Lécolle, Katia, Caillierez, Raphaëlle, Bégard, Séverine, Zommer, Nadège, Lachaud, Cédrick, Carrier, Sébastien, Dufour, Noëlle, Aurégan, Gwennaëlle, Winderickx, Joris, Hantraye, Philippe, Déglon, Nicole, Colin, Morvane, Buée, Luc
Published in Acta neuropathologica communications (30.01.2014)
Published in Acta neuropathologica communications (30.01.2014)
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Journal Article
Recent Insights on Alzheimer's Disease Originating from Yeast Models
Seynnaeve, David, Vecchio, Mara Del, Fruhmann, Gernot, Verelst, Joke, Cools, Melody, Beckers, Jimmy, Mulvihill, Daniel P, Winderickx, Joris, Franssens, Vanessa
Published in International journal of molecular sciences (03.07.2018)
Published in International journal of molecular sciences (03.07.2018)
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Journal Article
Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in Saccharomyces cerevisiae
Kipanga, Purity N., Demuyser, Liesbeth, Vrijdag, Johannes, Eskes, Elja, D’hooge, Petra, Matasyoh, Josphat, Callewaert, Geert, Winderickx, Joris, Van Dijck, Patrick, Luyten, Walter
Published in International journal of molecular sciences (28.05.2021)
Published in International journal of molecular sciences (28.05.2021)
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Journal Article
pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity
Deprez, Marie-Anne, Eskes, Elja, Wilms, Tobias, Ludovico, Paula, Winderickx, Joris
Published in Microbial cell (12.01.2018)
Published in Microbial cell (12.01.2018)
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Journal Article
Decreased Vacuolar Ca2+ Storage and Disrupted Vesicle Trafficking Underlie Alpha-Synuclein-Induced Ca2+ Dysregulation in S. cerevisiae
Callewaert, Geert, D’hooge, Petra, Ma, Tien-Yang, Del Vecchio, Mara, Van Eyck, Vincent, Franssens, Vanessa, Winderickx, Joris
Published in Frontiers in genetics (08.05.2020)
Published in Frontiers in genetics (08.05.2020)
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The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?
Fichou, Yann, Al-Hilaly, Youssra K, Devred, François, Smet-Nocca, Caroline, Tsvetkov, Philipp O, Verelst, Joke, Winderickx, Joris, Geukens, Nick, Vanmechelen, Eugeen, Perrotin, Audrey, Serpell, Louise, Hanseeuw, Bernard J, Medina, Miguel, Buée, Luc, Landrieu, Isabelle
Published in Acta neuropathologica communications (01.03.2019)
Published in Acta neuropathologica communications (01.03.2019)
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Journal Article
The Impact of ESCRT on Aβ1-42 Induced Membrane Lesions in a Yeast Model for Alzheimer’s Disease
Fruhmann, Gernot, Marchal, Christelle, Vignaud, Hélène, Verduyckt, Mathias, Talarek, Nicolas, De Virgilio, Claudio, Winderickx, Joris, Cullin, Christophe
Published in Frontiers in molecular neuroscience (05.11.2018)
Published in Frontiers in molecular neuroscience (05.11.2018)
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