Model-Based Prediction of Phase III Overall Survival in Colorectal Cancer on the Basis of Phase II Tumor Dynamics
CLARET, Laurent, GIRARD, Pascal, HOFF, Paulo M, VAN CUTSEM, Eric, ZUIDEVELD, Klaas P, JORGA, Karin, FAGERBERG, Jan, BRUNO, René
Published in Journal of clinical oncology (01.09.2009)
Published in Journal of clinical oncology (01.09.2009)
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Journal Article
A Guide to Rational Dosing of Monoclonal Antibodies
Bai, Shuang, Jorga, Karin, Xin, Yan, Jin, Denise, Zheng, Yanan, Damico-Beyer, Lisa A., Gupta, Manish, Tang, Meina, Allison, David E., Lu, Dan, Zhang, Yi, Joshi, Amita, Dresser, Mark J.
Published in Clinical pharmacokinetics (01.02.2012)
Published in Clinical pharmacokinetics (01.02.2012)
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Journal Article
A novel strategy for physiologically based predictions of human pharmacokinetics
JONES, Hannah M, PARROTF, Neil, JORGA, Karin, LAVE, Thierry
Published in Clinical pharmacokinetics (01.01.2006)
Published in Clinical pharmacokinetics (01.01.2006)
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Journal Article
Pediatric Dosing of Ganciclovir and Valganciclovir: How Model‐Based Simulations Can Prevent Underexposure and Potential Treatment Failure
Jorga, Karin, Reigner, Bruno, Chavanne, Clarisse, Alvaro, Giuseppe, Frey, Nicolas
Published in CPT: pharmacometrics and systems pharmacology (01.03.2019)
Published in CPT: pharmacometrics and systems pharmacology (01.03.2019)
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Journal Article
Model‐informed drug development of voxelotor in sickle cell disease: Exposure‐response analysis to support dosing and confirm mechanism of action
Green, Michelle L., Savic, Radojka M., Tonda, Margaret, Jorga, Karin, Washington, Carla B.
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
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Journal Article
Model‐informed drug development of voxelotor in sickle cell disease: Population pharmacokinetics in whole blood and plasma
Savic, Radojka M., Green, Michelle L., Jorga, Karin, Zager, Michael, Washington, Carla B.
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
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Journal Article
A Single Dose Mass Balance Study of the Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Humans Using Accelerator Mass Spectrometry
GRAHAM, Richard A, LUM, Bert L, MINLI XIE, LOW, Jennifer A, HOP, Cornelis E. C. A, MORRISON, Glenn, CHANG, Ilsung, JORGA, Karin, DEAN, Brian, SHIN, Young G, QIN YUE, MULDER, Teresa, MALHI, Vikram
Published in Drug metabolism and disposition (01.08.2011)
Published in Drug metabolism and disposition (01.08.2011)
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Journal Article
An integrated glucose-insulin model to describe oral glucose tolerance test data in type 2 diabetics
Jauslin, Petra M, Silber, Hanna E, Frey, Nicolas, Gieschke, Ronald, Simonsson, Ulrika S H, Jorga, Karin, Karlsson, Mats O
Published in Journal of clinical pharmacology (01.10.2007)
Published in Journal of clinical pharmacology (01.10.2007)
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Journal Article
Metabolism and excretion of tolcapone, a novel inhibitor of catechol‐O‐methyltransferase
Jorga, Karin, Fotteler, Bärbel, Heizmann, Peter, Gasser, Rodolfo
Published in British journal of clinical pharmacology (01.10.1999)
Published in British journal of clinical pharmacology (01.10.1999)
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Journal Article
Lack of interaction between tolcapone and tolbutamide in healthy volunteers
Jorga, K M, Fotteler, B, Gasser, R, Banken, L, Birnboeck, H
Published in Journal of clinical pharmacology (01.05.2000)
Published in Journal of clinical pharmacology (01.05.2000)
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Journal Article
Abstract 382: Concomitant administration of acid reducing agents can impact the pharmacokinetics of the balanced pan-PI3K and mTOR inhibitor PQR309
Jorga, Karin, Huehn, Eva, Fraczkiewicz, Grace, Schmitz, Debora, Fabbro, Doriano, Dimitrijevic, Sasa
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Pharmacokinetics of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Locally Advanced or Metastatic Solid Tumors: the Role of Alpha-1-Acid Glycoprotein Binding
GRAHAM, Richard A, LUM, Bert L, CHEETI, Sravanthi, JIN YAN JIN, JORGA, Karin, VON HOFF, Daniel D, RUDIN, Charles M, REDDY, Josina C, LOW, Jennifer A, LORUSSO, Patricia M
Published in Clinical cancer research (15.04.2011)
Published in Clinical cancer research (15.04.2011)
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Journal Article
The Effect of COMT Inhibition by Tolcapone on Tolerability and Pharmacokinetics of Different Levodopa/Benserazide Formulations
Jorga, Karin, Fotteler, Bärbel, Schmitt, Monique, Nielsen, Thorkild, Zürcher, Gerhard, Aitken, John
Published in European neurology (01.01.1997)
Published in European neurology (01.01.1997)
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Journal Article
Predicting sustained virological response and anaemia in chronic hepatitis C patients treated with peginterferon alfa‐2a (40KD) plus ribavirin
Snoeck, Eric, Wade, Janet R., Duff, Frank, Lamb, Matthew, Jorga, Karin
Published in British journal of clinical pharmacology (01.12.2006)
Published in British journal of clinical pharmacology (01.12.2006)
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Journal Article