Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine
Theisen, Michael, Jore, Matthijs M, Sauerwein, Robert
Published in Expert review of vaccines (01.04.2017)
Published in Expert review of vaccines (01.04.2017)
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A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial
Alkema, M, Smit, M J, Marin-Mogollon, C, Totté, K, Teelen, K, van Gemert, G J, van de Vegte-Bolmer, M, Mordmüller, B G, Reimer, J M, Lövgren-Bengtsson, K L, Sauerwein, R W, Bousema, T, Plieskatt, J, Theisen, M, Jore, M M, McCall, M B B
Published in BMC medicine (23.04.2024)
Published in BMC medicine (23.04.2024)
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Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
Semenova, Ekaterina, Jore, Matthijs M, Datsenko, Kirill A, Semenova, Anna, Westra, Edze R, Wanner, Barry, van der Oost, John, Brouns, Stan J.J, Severinov, Konstantin
Published in Proceedings of the National Academy of Sciences - PNAS (21.06.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (21.06.2011)
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Structural basis for therapeutic inhibition of complement C5
Jore, Matthijs M, Johnson, Steven, Sheppard, Devon, Barber, Natalie M, Li, Yang I, Nunn, Miles A, Elmlund, Hans, Lea, Susan M
Published in Nature structural & molecular biology (01.05.2016)
Published in Nature structural & molecular biology (01.05.2016)
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CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3
Westra, Edze R., van Erp, Paul B.G., Künne, Tim, Wong, Shi Pey, Staals, Raymond H.J., Seegers, Christel L.C., Bollen, Sander, Jore, Matthijs M., Semenova, Ekaterina, Severinov, Konstantin, de Vos, Willem M., Dame, Remus T., de Vries, Renko, Brouns, Stan J.J., van der Oost, John
Published in Molecular cell (08.06.2012)
Published in Molecular cell (08.06.2012)
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Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies
Ko, Kuang-Ting, Lennartz, Frank, Mekhaiel, David, Guloglu, Bora, Marini, Arianna, Deuker, Danielle J., Long, Carole A., Jore, Matthijs M., Miura, Kazutoyo, Biswas, Sumi, Higgins, Matthew K.
Published in Nature communications (24.09.2022)
Published in Nature communications (24.09.2022)
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Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
Brouns, Stan J.J, Jore, Matthijs M, Lundgren, Magnus, Westra, Edze R, Slijkhuis, Rik J.H, Snijders, Ambrosius P.L, Dickman, Mark J, Makarova, Kira S, Koonin, Eugene V, van der Oost, John
Published in Science (American Association for the Advancement of Science) (15.08.2008)
Published in Science (American Association for the Advancement of Science) (15.08.2008)
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Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45
Kundu, Prasun, Semesi, Anthony, Jore, Matthijs M., Morin, Merribeth J., Price, Virginia L., Liang, Alice, Li, Jingxing, Miura, Kazutoyo, Sauerwein, Robert W., King, C. Richter, Julien, Jean-Philippe
Published in Nature communications (26.10.2018)
Published in Nature communications (26.10.2018)
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Structure and function of a family of tick-derived complement inhibitors targeting properdin
Braunger, Katharina, Ahn, Jiyoon, Jore, Matthijs M., Johnson, Steven, Tang, Terence T. L., Pedersen, Dennis V., Andersen, Gregers R., Lea, Susan M.
Published in Nature communications (14.01.2022)
Published in Nature communications (14.01.2022)
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Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum
Singh, Susheel K., Thrane, Susan, Chourasia, Bishwanath K., Teelen, Karina, Graumans, Wouter, Stoter, Rianne, van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga G., Nielsen, Morten A., Salanti, Ali, Sander, Adam F., Sauerwein, Robert W., Jore, Matthijs M., Theisen, Michael
Published in Frontiers in immunology (05.06.2019)
Published in Frontiers in immunology (05.06.2019)
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Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody
Lennartz, Frank, Brod, Florian, Dabbs, Rebecca, Miura, Kazutoyo, Mekhaiel, David, Marini, Arianna, Jore, Matthijs M., Søgaard, Max M., Jørgensen, Thomas, de Jongh, Willem A., Sauerwein, Robert W., Long, Carole A., Biswas, Sumi, Higgins, Matthew K.
Published in Nature communications (20.09.2018)
Published in Nature communications (20.09.2018)
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A Reproducible and Scalable Process for Manufacturing a Pfs48/45 Based Plasmodium falciparum Transmission-Blocking Vaccine
Singh, Susheel K, Plieskatt, Jordan, Chourasia, Bishwanath K, Fabra-García, Amanda, Garcia-Senosiain, Asier, Singh, Vandana, Bengtsson, Karin Lövgren, Reimer, Jenny M, Sauerwein, Robert, Jore, Matthijs M, Theisen, Michael
Published in Frontiers in immunology (11.01.2021)
Published in Frontiers in immunology (11.01.2021)
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RNA in defense: CRISPRs protect prokaryotes against mobile genetic elements
Jore, Matthijs M, Brouns, Stan J J, van der Oost, John
Published in Cold Spring Harbor perspectives in biology (01.06.2012)
Published in Cold Spring Harbor perspectives in biology (01.06.2012)
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Heterologous Expression and Evaluation of Novel Plasmodium falciparum Transmission Blocking Vaccine Candidates
de Jong, Roos M., Singh, Susheel K., Teelen, Karina, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, Stone, Will J. R., Locke, Emily, Plieskatt, Jordan, Theisen, Michael, Bousema, Teun, Jore, Matthijs M.
Published in Frontiers in immunology (23.06.2022)
Published in Frontiers in immunology (23.06.2022)
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Native Tandem and Ion Mobility Mass Spectrometry Highlight Structural and Modular Similarities in Clustered-Regularly-Interspaced Shot-Palindromic-Repeats (CRISPR)-associated Protein Complexes From Escherichia coli and Pseudomonas aeruginosa
van Duijn, Esther, Barbu, Ioana M., Barendregt, Arjan, Jore, Matthijs M., Wiedenheft, Blake, Lundgren, Magnus, Westra, Edze R., Brouns, Stan J.J., Doudna, Jennifer A., van der Oost, John, Heck, Albert J.R.
Published in Molecular & cellular proteomics (01.11.2012)
Published in Molecular & cellular proteomics (01.11.2012)
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Naturally acquired antibodies to gametocyte antigens are associated with reduced transmission of Plasmodium vivax gametocytes to Anopheles arabiensis mosquitoes
Tebeje, Surafel K, Chali, Wakweya, Hailemeskel, Elifaged, Ramjith, Jordache, Gashaw, Abrham, Ashine, Temesgen, Nebret, Desalegn, Esayas, Endashaw, Emiru, Tadele, Tsegaye, Tizita, Teelen, Karina, Lanke, Kjerstin, Takashima, Eizo, Tsuboi, Takafumi, Salinas, Nichole D, Tolia, Niraj H, Narum, David, Drakeley, Chris, Witkowski, Benoit, Vantaux, Amelie, Jore, Matthijs M, Stone, William J R, Hansen, Ivo S, Tadesse, Fitsum G, Bousema, Teun
Published in Frontiers in cellular and infection microbiology (16.01.2023)
Published in Frontiers in cellular and infection microbiology (16.01.2023)
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Redistribution of membrane proteins between the Golgi apparatus and endoplasmic reticulum in plants is reversible and not dependent on cytoskeletal networks
Saint‐Jore, Claude M., Evins, Janet, Batoko, Henri, Brandizzi, Federica, Moore, Ian, Hawes, Chris
Published in The Plant journal : for cell and molecular biology (01.03.2002)
Published in The Plant journal : for cell and molecular biology (01.03.2002)
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Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine
Singh, Susheel K., Plieskatt, Jordan, Chourasia, Bishwanath K., Singh, Vandana, Bengtsson, Karin Lövgren, Reimer, Jenny M., van Daalen, Renate C., Teelen, Karina, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, Jore, Matthijs M., Theisen, Michael
Published in npj vaccines (12.10.2021)
Published in npj vaccines (12.10.2021)
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