Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq)
Mahat, Dig Bijay, Kwak, Hojoong, Booth, Gregory T, Jonkers, Iris H, Danko, Charles G, Patel, Ravi K, Waters, Colin T, Munson, Katie, Core, Leighton J, Lis, John T
Published in Nature protocols (01.08.2016)
Published in Nature protocols (01.08.2016)
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An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cells
Moerkens, Renée, Mooiweer, Joram, Ramírez-Sánchez, Aarón D., Oelen, Roy, Franke, Lude, Wijmenga, Cisca, Barrett, Robert J., Jonkers, Iris H., Withoff, Sebo
Published in Cell reports (Cambridge) (23.07.2024)
Published in Cell reports (Cambridge) (23.07.2024)
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Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Pediatric Coeliac Disease Patients Suggests Potential Pre-Seroconversion Markers
Ramírez-Sánchez, Aarón D, Chu, Xiaojing, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Koletzko, Sibylle, Korponay-Szabó, Ilma R, Troncone, Riccardo, Wijmenga, Cisca, Mearin, Luisa, Withoff, Sebo, Jonkers, Iris H, Li, Yang
Published in Frontiers in immunology (15.03.2022)
Published in Frontiers in immunology (15.03.2022)
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Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.
Published in Scientific reports (29.04.2021)
Published in Scientific reports (29.04.2021)
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iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies
Palasantzas, Victoria E.J.M., Tamargo-Rubio, Isabel, Le, Kieu, Slager, Jelle, Wijmenga, Cisca, Jonkers, Iris H., Kumar, Vinod, Fu, Jingyuan, Withoff, Sebo
Published in Trends in genetics (01.04.2023)
Published in Trends in genetics (01.04.2023)
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Human organoids and organ-on-chips in coeliac disease research
Simpson, Hanna L., Smits, Eline, Moerkens, Renée, Wijmenga, Cisca, Mooiweer, Joram, Jonkers, Iris H., Withoff, Sebo
Published in Trends in molecular medicine (23.10.2024)
Published in Trends in molecular medicine (23.10.2024)
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Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis
Shaw, Dustin G., Aguirre-Gamboa, Raúl, Vieira, Marcos C., Gona, Saideep, DiNardi, Nicholas, Wang, Anni, Dumaine, Anne, Gelderloos-Arends, Jody, Earley, Zachary M., Meckel, Katherine R., Ciszewski, Cezary, Castillo, Anabella, Monroe, Kelly, Torres, Joana, Shah, Shailja C., Colombel, Jean-Frédéric, Itzkowitz, Steven, Newberry, Rodney, Cohen, Russell D., Rubin, David T., Quince, Christopher, Cobey, Sarah, Jonkers, Iris H., Weber, Christopher R., Pekow, Joel, Wilson, Patrick C., Barreiro, Luis B., Jabri, Bana
Published in Nature medicine (01.06.2023)
Published in Nature medicine (01.06.2023)
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Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease
Chu, Xiaojing, Jaeger, Martin, Beumer, Joep, Bakker, Olivier B, Aguirre-Gamboa, Raul, Oosting, Marije, Smeekens, Sanne P, Moorlag, Simone, Mourits, Vera P, Koeken, Valerie A C M, de Bree, Charlotte, Jansen, Trees, Mathews, Ian T, Dao, Khoi, Najhawan, Mahan, Watrous, Jeramie D, Joosten, Irma, Sharma, Sonia, Koenen, Hans J P M, Withoff, Sebo, Jonkers, Iris H, Netea-Maier, Romana T, Xavier, Ramnik J, Franke, Lude, Xu, Cheng-Jian, Joosten, Leo A B, Sanna, Serena, Jain, Mohit, Kumar, Vinod, Clevers, Hans, Wijmenga, Cisca, Netea, Mihai G, Li, Yang
Published in Genome Biology (06.07.2021)
Published in Genome Biology (06.07.2021)
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Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes
Zorro, Maria Magdalena, Aguirre-Gamboa, Raul, Mayassi, Toufic, Ciszewski, Cezary, Barisani, Donatella, Hu, Shixian, Weersma, Rinse K, Withoff, Sebo, Li, Yang, Wijmenga, Cisca, Jabri, Bana, Jonkers, Iris H
Published in Journal of autoimmunity (01.03.2020)
Published in Journal of autoimmunity (01.03.2020)
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Genetic mapping across autoimmune diseases reveals shared associations and mechanisms
Lincoln, Matthew R., Connally, Noah, Axisa, Pierre-Paul, Gasperi, Christiane, Mitrovic, Mitja, van Heel, David, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H., Padyukov, Leonid, Rich, Stephen S., Graham, Robert R., Gaffney, Patrick M., Langefeld, Carl D., Vyse, Timothy J., Hafler, David A., Chun, Sung, Sunyaev, Shamil R., Cotsapas, Chris
Published in Nature genetics (13.05.2024)
Published in Nature genetics (13.05.2024)
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Potential biomarkers for multiple sclerosis stage from targeted proteomics and microRNA sequencing
Tan, Ineke L, Modderman, Rutger, Stachurska, Anna, Almeida, Rodrigo, de Vries, Riemer, Heersema, Dorothea J, Gacesa, Ranko, Wijmenga, Cisca, Jonkers, Iris H, Meilof, Jan F, Withoff, Sebo
Published in Brain communications (2024)
Published in Brain communications (2024)
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Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs
Ricaño-Ponce, Isis, Zhernakova, Daria V, Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M, Gutierrez-Achury, Javier, Uitterlinden, Andre G, Hofman, Albert, van Meurs, Joyce, Netea, Mihai G, Jonkers, Iris H, Withoff, Sebo, van Duijn, Cornelia M, Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Published in Journal of autoimmunity (01.04.2016)
Published in Journal of autoimmunity (01.04.2016)
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