Role of Breast Cancer Resistance Protein in the Bioavailability and Fetal Penetration of Topotecan
Jonker, Johan W., Smit, Johan W., Brinkhuis, Remco F., Maliepaard, Marc, Beijnen, Jos H., Schellens, Jan H. M., Schinkel, Alfred H.
Published in JNCI : Journal of the National Cancer Institute (18.10.2000)
Published in JNCI : Journal of the National Cancer Institute (18.10.2000)
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Journal Article
Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene
Jonker, Johan W., Wagenaar, Els, Mol, Carla A. A. M., Buitelaar, Marije, Koepsell, Hermann, Smit, Johan W., Schinkel, Alfred H.
Published in Molecular and Cellular Biology (01.08.2001)
Published in Molecular and Cellular Biology (01.08.2001)
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Journal Article
Role of blood‐brain barrier P‐glycoprotein in limiting brain accumulation and sedative side‐effects of asimadoline, a peripherally acting analgaesic drug
Jonker, J W, Wagenaar, E, Van Deemter, L, Gottschlich, R, Bender, H M, Dasenbrock, J, Schinkel, A H
Published in British journal of pharmacology (01.05.1999)
Published in British journal of pharmacology (01.05.1999)
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P-glycoprotein and Mrp1 collectively protect the bone marrow from vincristine-induced toxicity in vivo
van Tellingen, O, Buckle, T, Jonker, J W, van der Valk, M A, Beijnen, J H
Published in British journal of cancer (03.11.2003)
Published in British journal of cancer (03.11.2003)
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Journal Article
TUB gene expression in hypothalamus and adipose tissue and its association with obesity in humans
Nies, V J M, Struik, D, Wolfs, M G M, Rensen, S S, Szalowska, E, Unmehopa, U A, Fluiter, K, van der Meer, T P, Hajmousa, G, Buurman, W A, Greve, J W, Rezaee, F, Shiri-Sverdlov, R, Vonk, R J, Swaab, D F, Wolffenbuttel, B H R, Jonker, J W, van Vliet-Ostaptchouk, J V
Published in International Journal of Obesity (01.03.2018)
Published in International Journal of Obesity (01.03.2018)
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Journal Article
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
Schinkel, Alfred H, Jonker, Johan W, Merino, Gracia, Musters, Sandra, van Herwaarden, Antonius E, Bolscher, Ellen, Wagenaar, Els, Mesman, Elly, Dale, Trevor C
Published in Nature medicine (01.02.2005)
Published in Nature medicine (01.02.2005)
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The Breast Cancer Resistance Protein Protects against a Major Chlorophyll-Derived Dietary Phototoxin and Protoporphyria
Jonker, Johan W., Buitelaar, Marije, Wagenaar, Els, van der Valk, Martin A., Scheffer, George L., Scheper, Rik J., Plösch, Torsten, Kuipers, Folkert, Ronald P.J. Oude Elferink, Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2002)
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Investigation of Efflux Transport of Dehydroepiandrosterone Sulfate and Mitoxantrone at the Mouse Blood-Brain Barrier: A Minor Role of Breast Cancer Resistance Protein
Lee, Young-Joo, Kusuhara, Hiroyuki, Jonker, Johan W, Schinkel, Alfred H, Sugiyama, Yuichi
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
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Journal Article
Transport of Topoisomerase I Inhibitors by the Breast Cancer Resistance Protein: Potential Clinical Implications
SCHELLENS, JAN H.M., MALIEPAARD, MARC, SCHEPER, RIK J., SCHEFFER, GEORGE L., JONKER, JOHAN W., SMIT, JOHAN W., BEIJNEN, JOS H., SCHINKEL, ALFRED H.
Published in Annals of the New York Academy of Sciences (01.01.2000)
Published in Annals of the New York Academy of Sciences (01.01.2000)
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Initiation of cellulose biosynthesis
Manley, R S, Jonker, J W, Cooper, D, Pound, T C
Published in Nature. New biology (London) (20.01.1971)
Published in Nature. New biology (London) (20.01.1971)
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Human Breast Cancer Resistance Protein: Interactions with Steroid Drugs, Hormones, the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and Transport of Cimetidine
Pavek, Petr, Merino, Gracia, Wagenaar, Els, Bolscher, Ellen, Novotna, Martina, Jonker, Johan W, Schinkel, Alfred H
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
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The Breast Cancer Resistance Protein (BCRP/ABCG2) Affects Pharmacokinetics, Hepatobiliary Excretion, and Milk Secretion of the Antibiotic Nitrofurantoin
Merino, Gracia, Jonker, Johan W, Wagenaar, Els, van Herwaarden, Antonius E, Schinkel, Alfred H
Published in Molecular pharmacology (01.05.2005)
Published in Molecular pharmacology (01.05.2005)
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Journal Article
Involvement of Organic Cation Transporter 1 in Hepatic and Intestinal Distribution of Metformin
Wang, De-Sheng, Jonker, Johan W, Kato, Yukio, Kusuhara, Hiroyuki, Schinkel, Alfred H, Sugiyama, Yuichi
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
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Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk
Herwaarden, Antonius E.van, Wagenaar, Els, Karnekamp, Barbara, Merino, Gracia, Jonker, Johan W., Schinkel, Alfred H.
Published in Carcinogenesis (New York) (01.01.2006)
Published in Carcinogenesis (New York) (01.01.2006)
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