Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
Castelo-Branco, Pedro, PhD, Choufani, Sanaa, PhD, Mack, Stephen, BSc, Gallagher, Denis, PhD, Zhang, Cindy, MSc, Lipman, Tatiana, MSc, Zhukova, Nataliya, MD, Walker, Erin J, PhD, Martin, Dianna, PhD, Merino, Diana, MSc, Wasserman, Jonathan D, MD, Elizabeth, Cynthia, MSc, Alon, Noa, BSc, Zhang, Libo, PhD, Hovestadt, Volker, MSc, Kool, Marcel, PhD, Jones, David TW, PhD, Zadeh, Gelareh, MD, Croul, Sidney, Prof, Hawkins, Cynthia, MD, Hitzler, Johann, MD, Wang, Jean CY, MD, Baruchel, Sylvain, Prof, Dirks, Peter B, Prof, Malkin, David, Prof, Pfister, Stefan, MD, Taylor, Michael D, MD, Weksberg, Rosanna, Prof, Tabori, Uri, Dr
Published in The lancet oncology (01.05.2013)
Published in The lancet oncology (01.05.2013)
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Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
Liu, Xiao-Yang, Gerges, Noha, Korshunov, Andrey, Sabha, Nesrin, Khuong-Quang, Dong-Anh, Fontebasso, Adam M., Fleming, Adam, Hadjadj, Djihad, Schwartzentruber, Jeremy, Majewski, Jacek, Dong, Zhifeng, Siegel, Peter, Albrecht, Steffen, Croul, Sidney, Jones, David TW, Kool, Marcel, Tonjes, Martje, Reifenberger, Guido, Faury, Damien, Zadeh, Gelareh, Pfister, Stefan, Jabado, Nada
Published in Acta neuropathologica (01.11.2012)
Published in Acta neuropathologica (01.11.2012)
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Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants
Wegert, Jenny, Vokuhl, Christian, Collord, Grace, Del Castillo Velasco-Herrera, Martin, Farndon, Sarah J., Guzzo, Charlotte, Jorgensen, Mette, Anderson, John, Slater, Olga, Duncan, Catriona, Bausenwein, Sabrina, Streitenberger, Heike, Ziegler, Barbara, Furtwängler, Rhoikos, Graf, Norbert, Stratton, Michael R., Campbell, Peter J., Jones, David TW, Koelsche, Christian, Pfister, Stefan M., Mifsud, William, Sebire, Neil, Sparber-Sauer, Monika, Koscielniak, Ewa, Rosenwald, Andreas, Gessler, Manfred, Behjati, Sam
Published in Nature communications (18.06.2018)
Published in Nature communications (18.06.2018)
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FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
Suryo Rahmanto, Aldwin, Savov, Vasil, Brunner, Andrä, Bolin, Sara, Weishaupt, Holger, Malyukova, Alena, Rosén, Gabriela, Čančer, Matko, Hutter, Sonja, Sundström, Anders, Kawauchi, Daisuke, Jones, David TW, Spruck, Charles, Taylor, Michael D, Cho, Yoon-Jae, Pfister, Stefan M, Kool, Marcel, Korshunov, Andrey, Swartling, Fredrik J, Sangfelt, Olle
Published in The EMBO journal (17.10.2016)
Published in The EMBO journal (17.10.2016)
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Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplifications
Kommoss, Felix KF, Chang, Kenneth TE, Stichel, Damian, Banito, Ana, Jones, David TW, Heilig, Christoph E, Fröhling, Stefan, Sahm, Felix, Stenzinger, Albrecht, Hartmann, Wolfgang, Mechtersheimer, Gunhild, Sinn, Hans‐Peter, Schmidt, Dietmar, Kommoss, Friedrich, Deimling, Andreas, Koelsche, Christian
Published in The journal of pathology. Clinical research (01.07.2020)
Published in The journal of pathology. Clinical research (01.07.2020)
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EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors
Dudvarski Stanković, Nevenka, Bicker, Frank, Keller, Stefanie, Jones, David TW, Harter, Patrick N, Kienzle, Arne, Gillmann, Clarissa, Arnold, Philipp, Golebiewska, Anna, Keunen, Olivier, Giese, Alf, von Deimling, Andreas, Bäuerle, Tobias, Niclou, Simone P, Mittelbronn, Michel, Ye, Weilan, Pfister, Stefan M, Schmidt, Mirko HH
Published in EMBO molecular medicine (01.09.2018)
Published in EMBO molecular medicine (01.09.2018)
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Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge
Sturm, Dominik, Bender, Sebastian, Jones, David T. W., Lichter, Peter, Grill, Jacques, Becher, Oren, Hawkins, Cynthia, Majewski, Jacek, Jones, Chris, Costello, Joseph F., Iavarone, Antonio, Aldape, Kenneth, Brennan, Cameron W., Jabado, Nada, Pfister, Stefan M.
Published in Nature reviews. Cancer (01.02.2014)
Published in Nature reviews. Cancer (01.02.2014)
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Pilocytic astrocytoma: pathology, molecular mechanisms and markers
Collins, V. Peter, Jones, David T. W., Giannini, Caterina
Published in Acta neuropathologica (01.06.2015)
Published in Acta neuropathologica (01.06.2015)
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ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma
Reuss, David E., Sahm, Felix, Schrimpf, Daniel, Wiestler, Benedikt, Capper, David, Koelsche, Christian, Schweizer, Leonille, Korshunov, Andrey, Jones, David T. W., Hovestadt, Volker, Mittelbronn, Michel, Schittenhelm, Jens, Herold-Mende, Christel, Unterberg, Andreas, Platten, Michael, Weller, Michael, Wick, Wolfgang, Pfister, Stefan M., von Deimling, Andreas
Published in Acta neuropathologica (01.01.2015)
Published in Acta neuropathologica (01.01.2015)
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Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway
Huse, Jason T., Snuderl, Matija, Jones, David T. W., Brathwaite, Carole D., Altman, Nolan, Lavi, Ehud, Saffery, Richard, Sexton-Oates, Alexandra, Blumcke, Ingmar, Capper, David, Karajannis, Matthias A., Benayed, Ryma, Chavez, Lukas, Thomas, Cheddhi, Serrano, Jonathan, Borsu, Laetitia, Ladanyi, Marc, Rosenblum, Marc K.
Published in Acta neuropathologica (01.03.2017)
Published in Acta neuropathologica (01.03.2017)
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Medulloblastomics: the end of the beginning
Northcott, Paul A., Jones, David T. W., Kool, Marcel, Robinson, Giles W., Gilbertson, Richard J., Cho, Yoon-Jae, Pomeroy, Scott L., Korshunov, Andrey, Lichter, Peter, Taylor, Michael D., Pfister, Stefan M.
Published in Nature reviews. Cancer (01.12.2012)
Published in Nature reviews. Cancer (01.12.2012)
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Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes
Johann, Pascal D., Erkek, Serap, Zapatka, Marc, Kerl, Kornelius, Buchhalter, Ivo, Hovestadt, Volker, Jones, David T.W., Sturm, Dominik, Hermann, Carl, Segura Wang, Maia, Korshunov, Andrey, Rhyzova, Marina, Gröbner, Susanne, Brabetz, Sebastian, Chavez, Lukas, Bens, Susanne, Gröschel, Stefan, Kratochwil, Fabian, Wittmann, Andrea, Sieber, Laura, Geörg, Christina, Wolf, Stefan, Beck, Katja, Oyen, Florian, Capper, David, van Sluis, Peter, Volckmann, Richard, Koster, Jan, Versteeg, Rogier, von Deimling, Andreas, Milde, Till, Witt, Olaf, Kulozik, Andreas E., Ebinger, Martin, Shalaby, Tarek, Grotzer, Michael, Sumerauer, David, Zamecnik, Josef, Mora, Jaume, Jabado, Nada, Taylor, Michael D., Huang, Annie, Aronica, Eleonora, Bertoni, Anna, Radlwimmer, Bernhard, Pietsch, Torsten, Schüller, Ulrich, Schneppenheim, Reinhard, Northcott, Paul A., Korbel, Jan O., Siebert, Reiner, Frühwald, Michael C., Lichter, Peter, Eils, Roland, Gajjar, Amar, Hasselblatt, Martin, Pfister, Stefan M., Kool, Marcel
Published in Cancer cell (14.03.2016)
Published in Cancer cell (14.03.2016)
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ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing
Jäger, Natalie, Jones, David TW, Kool, Marcel, Zichner, Thomas, Hutter, Barbara, Sultan, Marc, Cho, Yoon-Jae, Pugh, Trevor J, Hovestadt, Volker, Stütz, Adrian M, Rausch, Tobias, Warnatz, Hans-Jörg, Brors, Benedikt, Northcott, Paul A, Taylor, Michael D, Meyerson, Matthew, Pomeroy, Scott L, Yaspo, Marie-Laure, Korbel, Jan O, Korshunov, Andrey, Eils, Roland, Pfister, Stefan M, Lichter, Peter
Published in BMC proceedings (01.10.2012)
Published in BMC proceedings (01.10.2012)
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Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
Korshunov, Andrey, Ryzhova, Marina, Hovestadt, Volker, Bender, Sebastian, Sturm, Dominik, Capper, David, Meyer, Jochen, Schrimpf, Daniel, Kool, Marcel, Northcott, Paul A., Zheludkova, Olga, Milde, Till, Witt, Olaf, Kulozik, Andreas E., Reifenberger, Guido, Jabado, Nada, Perry, Arie, Lichter, Peter, von Deimling, Andreas, Pfister, Stefan M., Jones, David T. W.
Published in Acta neuropathologica (01.05.2015)
Published in Acta neuropathologica (01.05.2015)
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Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma
Olar, Adriana, Wani, Khalida M., Wilson, Charmaine D., Zadeh, Gelareh, DeMonte, Franco, Jones, David T. W., Pfister, Stefan M., Sulman, Erik P., Aldape, Kenneth D.
Published in Acta neuropathologica (01.03.2017)
Published in Acta neuropathologica (01.03.2017)
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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Schwartzentruber, Jeremy, Korshunov, Andrey, Liu, Xiao-Yang, Jones, David T. W., Pfaff, Elke, Jacob, Karine, Sturm, Dominik, Fontebasso, Adam M., Quang, Dong-Anh Khuong, Tönjes, Martje, Hovestadt, Volker, Albrecht, Steffen, Kool, Marcel, Nantel, Andre, Konermann, Carolin, Lindroth, Anders, Jäger, Natalie, Rausch, Tobias, Ryzhova, Marina, Korbel, Jan O., Hielscher, Thomas, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Ebinger, Martin, Schuhmann, Martin U., Scheurlen, Wolfram, Pekrun, Arnulf, Frühwald, Michael C., Roggendorf, Wolfgang, Kramm, Christoph, Dürken, Matthias, Atkinson, Jeffrey, Lepage, Pierre, Montpetit, Alexandre, Zakrzewska, Magdalena, Zakrzewski, Krzystof, Liberski, Pawel P., Dong, Zhifeng, Siegel, Peter, Kulozik, Andreas E., Zapatka, Marc, Guha, Abhijit, Malkin, David, Felsberg, Jörg, Reifenberger, Guido, von Deimling, Andreas, Ichimura, Koichi, Collins, V. Peter, Witt, Hendrik, Milde, Till, Witt, Olaf, Zhang, Cindy, Castelo-Branco, Pedro, Lichter, Peter, Faury, Damien, Tabori, Uri, Plass, Christoph, Majewski, Jacek, Pfister, Stefan M., Jabado, Nada
Published in Nature (London) (09.02.2012)
Published in Nature (London) (09.02.2012)
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Active medulloblastoma enhancers reveal subgroup-specific cellular origins
Lin, Charles Y., Erkek, Serap, Tong, Yiai, Yin, Linlin, Federation, Alexander J., Zapatka, Marc, Haldipur, Parthiv, Kawauchi, Daisuke, Risch, Thomas, Warnatz, Hans-Jörg, Worst, Barbara C., Ju, Bensheng, Orr, Brent A., Zeid, Rhamy, Polaski, Donald R., Segura-Wang, Maia, Waszak, Sebastian M., Jones, David T. W., Kool, Marcel, Hovestadt, Volker, Buchhalter, Ivo, Sieber, Laura, Johann, Pascal, Chavez, Lukas, Gröschel, Stefan, Ryzhova, Marina, Korshunov, Andrey, Chen, Wenbiao, Chizhikov, Victor V., Millen, Kathleen J., Amstislavskiy, Vyacheslav, Lehrach, Hans, Yaspo, Marie-Laure, Eils, Roland, Lichter, Peter, Korbel, Jan O., Pfister, Stefan M., Bradner, James E., Northcott, Paul A.
Published in Nature (London) (04.02.2016)
Published in Nature (London) (04.02.2016)
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Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities
Reuss, David E., Kratz, Annekathrin, Sahm, Felix, Capper, David, Schrimpf, Daniel, Koelsche, Christian, Hovestadt, Volker, Bewerunge-Hudler, Melanie, Jones, David T. W., Schittenhelm, Jens, Mittelbronn, Michel, Rushing, Elisabeth, Simon, Matthias, Westphal, Manfred, Unterberg, Andreas, Platten, Michael, Paulus, Werner, Reifenberger, Guido, Tonn, Joerg-Christian, Aldape, Kenneth, Pfister, Stefan M., Korshunov, Andrey, Weller, Michael, Herold-Mende, Christel, Wick, Wolfgang, Brandner, Sebastian, von Deimling, Andreas
Published in Acta neuropathologica (01.09.2015)
Published in Acta neuropathologica (01.09.2015)
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Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis
Korshunov, Andrey, Chavez, Lukas, Sharma, Tanvi, Ryzhova, Marina, Schrimpf, Daniel, Stichel, Damian, Capper, David, Sturm, Dominik, Kool, Marcel, Habel, Antje, Kleinschmidt‐DeMasters, Bette K., Rosenblum, Marc, Absalyamova, Oksana, Golanov, Andrey, Lichter, Peter, Pfister, Stefan M., Jones, David T.W., Perry, Arie, von Deimling, Andreas
Published in Brain pathology (Zurich, Switzerland) (01.09.2018)
Published in Brain pathology (Zurich, Switzerland) (01.09.2018)
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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Pugh, Trevor J., Weeraratne, Shyamal Dilhan, Archer, Tenley C., Pomeranz Krummel, Daniel A., Auclair, Daniel, Bochicchio, James, Carneiro, Mauricio O., Carter, Scott L., Cibulskis, Kristian, Erlich, Rachel L., Greulich, Heidi, Lawrence, Michael S., Lennon, Niall J., McKenna, Aaron, Meldrim, James, Ramos, Alex H., Ross, Michael G., Russ, Carsten, Shefler, Erica, Sivachenko, Andrey, Sogoloff, Brian, Stojanov, Petar, Tamayo, Pablo, Mesirov, Jill P., Amani, Vladimir, Teider, Natalia, Sengupta, Soma, Francois, Jessica Pierre, Northcott, Paul A., Taylor, Michael D., Yu, Furong, Crabtree, Gerald R., Kautzman, Amanda G., Gabriel, Stacey B., Getz, Gad, Jäger, Natalie, Jones, David T. W., Lichter, Peter, Pfister, Stefan M., Roberts, Thomas M., Meyerson, Matthew, Pomeroy, Scott L., Cho, Yoon-Jae
Published in Nature (London) (02.08.2012)
Published in Nature (London) (02.08.2012)
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