FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?
Carmeliet, Peter, Fischer, Christian, Mazzone, Massimiliano, Jonckx, Bart
Published in Nature reviews. Cancer (01.12.2008)
Published in Nature reviews. Cancer (01.12.2008)
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Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels
Fischer, Christian, Jonckx, Bart, Mazzone, Massimiliano, Zacchigna, Serena, Loges, Sonja, Pattarini, Lucia, Chorianopoulos, Emmanuel, Liesenborghs, Laurens, Koch, Marta, De Mol, Maria, Autiero, Monica, Wyns, Sabine, Plaisance, Stephane, Moons, Lieve, van Rooijen, Nico, Giacca, Mauro, Stassen, Jean-Marie, Dewerchin, Mieke, Collen, Desire, Carmeliet, Peter
Published in Cell (02.11.2007)
Published in Cell (02.11.2007)
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Robotic Assisted Cannulation of Occluded Retinal Veins
de Smet, Marc D, Meenink, Thijs C M, Janssens, Tom, Vanheukelom, Valerie, Naus, Gerrit J L, Beelen, Maarten J, Meers, Caroline, Jonckx, Bart, Stassen, Jean-Marie
Published in PloS one (27.09.2016)
Published in PloS one (27.09.2016)
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Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 2. THR-687
Vanhove, Marc, Wagner, Jean-Marc, Noppen, Bernard, Jonckx, Bart, Vermassen, Elke, Stitt, Alan W.
Published in Journal of pharmacokinetics and pharmacodynamics (01.12.2021)
Published in Journal of pharmacokinetics and pharmacodynamics (01.12.2021)
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Journal Article
Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease
Van de Veire, Sara, Stalmans, Ingeborg, Heindryckx, Femke, Oura, Hajimu, Tijeras-Raballand, Annemilaï, Schmidt, Thomas, Loges, Sonja, Albrecht, Imke, Jonckx, Bart, Vinckier, Stefan, Van Steenkiste, Christophe, Tugues, Sònia, Rolny, Charlotte, De Mol, Maria, Dettori, Daniela, Hainaud, Patricia, Coenegrachts, Lieve, Contreres, Jean-Olivier, Van Bergen, Tine, Cuervo, Henar, Xiao, Wei-Hong, Le Henaff, Carole, Buysschaert, Ian, Masouleh, Behzad Kharabi, Geerts, Anja, Schomber, Tibor, Bonnin, Philippe, Lambert, Vincent, Haustraete, Jurgen, Zacchigna, Serena, Rakic, Jean-Marie, Jiménez, Wladimiro, Noël, Agnes, Giacca, Mauro, Colle, Isabelle, Foidart, Jean-Michel, Tobelem, Gerard, Morales-Ruiz, Manuel, Vilar, José, Maxwell, Patrick, Vinores, Stanley A., Carmeliet, Geert, Dewerchin, Mieke, Claesson-Welsh, Lena, Dupuy, Evelyne, Van Vlierberghe, Hans, Christofori, Gerhard, Mazzone, Massimiliano, Detmar, Michael, Collen, Désiré, Carmeliet, Peter
Published in Cell (2010)
Published in Cell (2010)
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Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6
Loges, Sonja, Schmidt, Thomas, Tjwa, Marc, van Geyte, Katie, Lievens, Dirk, Lutgens, Esther, Vanhoutte, Davy, Borgel, Delphine, Plaisance, Stephane, Hoylaerts, Marc, Luttun, Aernout, Dewerchin, Mieke, Jonckx, Bart, Carmeliet, Peter
Published in Blood (18.03.2010)
Published in Blood (18.03.2010)
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Journal Article
Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models
Coulon, Stephanie, Legry, Vanessa, Heindryckx, Femke, Van Steenkiste, Christophe, Casteleyn, Christophe, Olievier, Kim, Libbrecht, Louis, Carmeliet, Peter, Jonckx, Bart, Stassen, Jean‐Marie, Van Vlierberghe, Hans, Leclercq, Isabelle, Colle, Isabelle, Geerts, Anja
Published in Hepatology (Baltimore, Md.) (01.05.2013)
Published in Hepatology (Baltimore, Md.) (01.05.2013)
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Robot‐assisted retinal vein cannulation in an in vivo porcine retinal vein occlusion model
Willekens, Koen, Gijbels, Andy, Schoevaerdts, Laurent, Esteveny, Laure, Janssens, Tom, Jonckx, Bart, Feyen, Jean H. M., Meers, Caroline, Reynaerts, Dominiek, Vander Poorten, Emmanuel, Stalmans, Peter
Published in Acta ophthalmologica (Oxford, England) (01.05.2017)
Published in Acta ophthalmologica (Oxford, England) (01.05.2017)
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Inhibition of placental growth factor improves surgical outcome of glaucoma surgery
Bergen, Tine, Jonckx, Bart, Hollanders, Karolien, Sijnave, Davine, Velde, Sarah, Vandewalle, Evelien, Moons, Lieve, Stassen, Jean‐Marie, Stalmans, Ingeborg
Published in Journal of cellular and molecular medicine (01.12.2013)
Published in Journal of cellular and molecular medicine (01.12.2013)
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Placental growth factor contributes to bronchial neutrophilic inflammation and edema in allergic asthma
Bobic, Sonja, Seys, Sven, De Vooght, Vanessa, Callebaut, Ina, Hox, Valerie, Dooms, Christophe, Vinckier, Stefan, Jonckx, Bart, Saint-Remy, Jean-Marie, Stassen, Jean-Marie, Bullens, Dominique M A, Ceuppens, Jan L, Carmeliet, Peter, Hellings, Peter W
Published in American journal of respiratory cell and molecular biology (01.06.2012)
Published in American journal of respiratory cell and molecular biology (01.06.2012)
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Journal Article
Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
Mazzone, Massimiliano, Dettori, Daniela, Leite de Oliveira, Rodrigo, Loges, Sonja, Schmidt, Thomas, Jonckx, Bart, Tian, Ya-Min, Lanahan, Anthony A., Pollard, Patrick, Ruiz de Almodovar, Carmen, De Smet, Frederik, Vinckier, Stefan, Aragonés, Julián, Debackere, Koen, Luttun, Aernout, Wyns, Sabine, Jordan, Benedicte, Pisacane, Alberto, Gallez, Bernard, Lampugnani, Maria Grazia, Dejana, Elisabetta, Simons, Michael, Ratcliffe, Peter, Maxwell, Patrick, Carmeliet, Peter
Published in Cell (06.03.2009)
Published in Cell (06.03.2009)
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Placental growth factor inhibition targets pulmonary angiogenesis and represents a therapy for hepatopulmonary syndrome in mice
Raevens, Sarah, Geerts, Anja, Paridaens, Annelies, Lefere, Sander, Verhelst, Xavier, Hoorens, Anne, Van Dorpe, Jo, Maes, Tania, Bracke, Ken R., Casteleyn, Christophe, Jonckx, Bart, Horvatits, Thomas, Fuhrmann, Valentin, Van Vlierberghe, Hans, Van Steenkiste, Christophe, Devisscher, Lindsey, Colle, Isabelle
Published in Hepatology (Baltimore, Md.) (01.08.2018)
Published in Hepatology (Baltimore, Md.) (01.08.2018)
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Journal Article
The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders
Hu, Tjing-Tjing, Vanhove, Marc, Porcu, Michaël, Van Hove, Inge, Van Bergen, Tine, Jonckx, Bart, Barbeaux, Philippe, Vermassen, Elke, Feyen, Jean H.M.
Published in Experimental eye research (01.03.2019)
Published in Experimental eye research (01.03.2019)
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Journal Article
Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties
Bono, Françoise, De Smet, Frederik, Herbert, Corentin, De Bock, Katrien, Georgiadou, Maria, Fons, Pierre, Tjwa, Marc, Alcouffe, Chantal, Ny, Annelii, Bianciotto, Marc, Jonckx, Bart, Murakami, Masahiro, Lanahan, Anthony A., Michielsen, Christof, Sibrac, David, Dol-Gleizes, Frédérique, Mazzone, Massimiliano, Zacchigna, Serena, Herault, Jean-Pascal, Fischer, Christian, Rigon, Patrice, Ruiz de Almodovar, Carmen, Claes, Filip, Blanc, Isabelle, Poesen, Koen, Zhang, Jie, Segura, Inmaculada, Gueguen, Geneviève, Bordes, Marie-Françoise, Lambrechts, Diether, Broussy, Roselyne, van de Wouwer, Marlies, Michaux, Corinne, Shimada, Toru, Jean, Isabelle, Blacher, Silvia, Noel, Agnès, Motte, Patrick, Rom, Eran, Rakic, Jean-Marie, Katsuma, Susumu, Schaeffer, Paul, Yayon, Avner, Van Schepdael, Ann, Schwalbe, Harald, Gervasio, Francesco Luigi, Carmeliet, Geert, Rozensky, Jef, Dewerchin, Mieke, Simons, Michael, Christopoulos, Arthur, Herbert, Jean-Marc, Carmeliet, Peter
Published in Cancer cell (15.04.2013)
Published in Cancer cell (15.04.2013)
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Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1 + Leukemia
Schmidt, Thomas, Masouleh, Behzad Kharabi, Loges, Sonja, Cauwenberghs, Sandra, Fraisl, Peter, Maes, Christa, Jonckx, Bart, De Keersmaecker, Kim, Kleppe, Maria, Tjwa, Marc, Schenk, Thomas, Vinckier, Stefan, Fragoso, Rita, De Mol, Maria, Beel, Karolien, Dias, Sérgio, Verfaillie, Catherine, Clark, Richard E., Brümmendorf, Tim H., Vandenberghe, Peter, Rafii, Shahin, Holyoake, Tessa, Hochhaus, Andreas, Cools, Jan, Karin, Michael, Carmeliet, Geert, Dewerchin, Mieke, Carmeliet, Peter
Published in Cancer cell (14.06.2011)
Published in Cancer cell (14.06.2011)
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Journal Article
Release of experimental retinal vein occlusions by direct intraluminal injection of ocriplasmin
de Smet, Marc D, Stassen, Jean Marie, Meenink, Thijs C M, Janssens, Tom, Vanheukelom, Valérie, Naus, Gerrit J L, Beelen, Maarten J, Jonckx, Bart
Published in British journal of ophthalmology (01.12.2016)
Published in British journal of ophthalmology (01.12.2016)
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Journal Article
Pharmacokinetics of ocriplasmin in vitreous
de Smet, Marc D, Jonckx, Bart, Vanhove, Marc, van Calster, Joachim, Stalmans, Peter, Stassen, Jean Marie
Published in Investigative ophthalmology & visual science (13.12.2012)
Published in Investigative ophthalmology & visual science (13.12.2012)
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Journal Article
Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma
Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Bogaerts, Eliene, Paridaens, Annelies, Van den Bussche, Anja, Raevens, Sarah, Verhelst, Xavier, Van Steenkiste, Christophe, Jonckx, Bart, Libbrecht, Louis, Geerts, Anja, Carmeliet, Peter, Van Vlierberghe, Hans
Published in BMC cancer (11.01.2016)
Published in BMC cancer (11.01.2016)
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