Human TCR-Binding Affinity is Governed by MHC Class Restriction
Cole, David K, Pumphrey, Nicholas J, Boulter, Jonathan M, Sami, Malkit, Bell, John I, Gostick, Emma, Price, David A, Gao, George F, Sewell, Andrew K, Jakobsen, Bent K
Published in Journal of Immunology (01.05.2007)
Published in Journal of Immunology (01.05.2007)
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Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region
Wooldridge, Linda, Lissina, Anna, Vernazza, Jonathan, Gostick, Emma, Laugel, Bruno, Hutchinson, Sarah L., Mirza, Fareed, Dunbar, P. Rod, Boulter, Jonathan M., Glick, Meir, Cerundolo, Vincenzo, van den Berg, Hugo A., Price, David A., Sewell, Andrew K.
Published in European journal of immunology (01.05.2007)
Published in European journal of immunology (01.05.2007)
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Design of Soluble Recombinant T Cell Receptors for Antigen Targeting and T Cell Inhibition
Laugel, Bruno, Boulter, Jonathan M., Lissin, Nikolai, Vuidepot, Annelise, Li, Yi, Gostick, Emma, Crotty, Laura E., Douek, Daniel C., Hemelaar, Joris, Price, David A., Jakobsen, Bent K., Sewell, Andrew K.
Published in The Journal of biological chemistry (21.01.2005)
Published in The Journal of biological chemistry (21.01.2005)
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The CD8 T Cell Coreceptor Exhibits Disproportionate Biological Activity at Extremely Low Binding Affinities
Hutchinson, Sarah L, Wooldridge, Linda, Tafuro, Sabrina, Laugel, Bruno, Glick, Meir, Boulter, Jonathan M, Jakobsen, Bent K, Price, David A, Sewell, Andrew K
Published in The Journal of biological chemistry (04.07.2003)
Published in The Journal of biological chemistry (04.07.2003)
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Potent T cell agonism mediated by a very rapid TCR/pMHC interaction
Boulter, Jonathan M., Schmitz, Nicole, Sewell, Andrew K., Godkin, Andrew J., Bachmann, Martin F., Gallimore, Awen M.
Published in European Journal of Immunology (01.03.2007)
Published in European Journal of Immunology (01.03.2007)
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Crystal structure of HLA‐A2402 complexed with a telomerase peptide
Cole, David K., Rizkallah, Pierre J., Gao, Feng, Watson, Neil I., Boulter, Jonathan M., Bell, John I., Sami, Malkit, Gao, George F., Jakobsen, Bent K.
Published in European Journal of Immunology (01.01.2006)
Published in European Journal of Immunology (01.01.2006)
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Functional and biophysical characterization of an HLA‐A6801‐restricted HIV‐specific T cell receptor
Gostick, Emma, Cole, David K., Hutchinson, Sarah L., Wooldridge, Linda, Tafuro, Sabrina, Laugel, Bruno, Lissina, Anna, Oxenius, Annette, Boulter, Jonathan M., Price, David A., Sewell, Andrew K.
Published in European Journal of Immunology (01.02.2007)
Published in European Journal of Immunology (01.02.2007)
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Directed evolution of human T-cell receptors with picomolar affinities by phage display
Boulter, Jonathan M, Li, Yi, Moysey, Ruth, Molloy, Peter E, Vuidepot, Anne-Lise, Mahon, Tara, Baston, Emma, Dunn, Steven, Liddy, Nathaniel, Jacob, Jansen, Jakobsen, Bent K
Published in Nature biotechnology (01.03.2005)
Published in Nature biotechnology (01.03.2005)
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Chen, Ji-Li, Stewart-Jones, Guillaume, Bossi, Giovanna, Lissin, Nikolai M, Wooldridge, Linda, Choi, Ed Man Lik, Held, Gerhard, Dunbar, P Rod, Esnouf, Robert M, Sami, Malkit, Boulter, Jonathan M, Rizkallah, Pierre, Renner, Christoph, Sewell, Andrew, van der Merwe, P Anton, Jakobsen, Bent K, Griffiths, Gillian, Jones, E Yvonne, Cerundolo, Vincenzo
Published in The Journal of experimental medicine (18.04.2005)
Published in The Journal of experimental medicine (18.04.2005)
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Stable, soluble T-cell receptor molecules for crystallization and therapeutics
Boulter, Jonathan M, Glick, Meir, Todorov, Penio T, Baston, Emma, Sami, Malkit, Rizkallah, Pierre, Jakobsen, Bent K
Published in Protein engineering (01.09.2003)
Published in Protein engineering (01.09.2003)
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TCR affinity and negative regulation limit autoimmunity
Ohashi, Pamela S, Gronski, Matthew A, Boulter, Jonathan M, Moskophidis, Demetrius, Nguyen, Linh T, Holmberg, Kaisa, Elford, Alisha R, Deenick, Elissa K, Kim, Hee O, Penninger, Josef M, Odermatt, Bernhard, Gallimore, Awen, Gascoigne, Nicholas R J
Published in Nature medicine (01.11.2004)
Published in Nature medicine (01.11.2004)
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Increased Peptide Contacts Govern High Affinity Binding of a Modified TCR Whilst Maintaining a Native pMHC Docking Mode
Cole, David K, Sami, Malkit, Scott, Daniel R, Rizkallah, Pierre J, Borbulevych, Oleg Y, Todorov, Penio T, Moysey, Ruth K, Jakobsen, Bent K, Boulter, Jonathan M, Baker, Brian M, Yi Li
Published in Frontiers in immunology (01.01.2013)
Published in Frontiers in immunology (01.01.2013)
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Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Sami, Malkit, Rizkallah, Pierre J., Dunn, Steve, Molloy, Peter, Moysey, Ruth, Vuidepot, Annelise, Baston, Emma, Todorov, Penio, Li, Yi, Gao, Feng, Boulter, Jonathan M., Jakobsen, Bent K.
Published in Protein engineering, design and selection (01.08.2007)
Published in Protein engineering, design and selection (01.08.2007)
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Amplification and one-step expression cloning of human T cell receptor genes
Moysey, Ruth, Vuidepot, Anne-Lise, Boulter, Jonathan M.
Published in Analytical biochemistry (15.03.2004)
Published in Analytical biochemistry (15.03.2004)
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Antagonism of cytotoxic T-lymphocyte activation by soluble CD8
Jakobsen, Bent K, Sewell, Andrew K, Gerth, Ulrich C, Price, David A, Purbhoo, Marco A, Boulter, Jonathan M, Gao, George F, Bell, John I, Phillips, Rodney E
Published in Nature medicine (01.04.1999)
Published in Nature medicine (01.04.1999)
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Complete mapping of a novel HLA A6801-restricted HIV-1 Tat epitope directly ex vivo with a rapid modified enzyme-linked immunospot assay
OXENIUS, Annette, JAKOBSEN, Bent K, EASTERBROOK, Philippa J, BOULTER, Jonathan M, TUN, Tin, WATERS, Anele, AGUDELO, Juliet, BARNARDO, Martin, PHILLIPS, Rodney E, PRICE, David A
Published in AIDS (London) (14.06.2002)
Published in AIDS (London) (14.06.2002)
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Classical and Nonclassical Class I Major Histocompatibility Complex Molecules Exhibit Subtle Conformational Differences That Affect Binding to CD8αα
Gao, George F., Willcox, Benjamin E., Wyer, Jessica R., Boulter, Jonathan M., O'Callaghan, Christopher A., Maenaka, Katsumi, Stuart, David I., Jones, E.Yvonne, Van Der Merwe, P.Anton, Bell, John I., Jakobsen, Bent K.
Published in The Journal of biological chemistry (19.05.2000)
Published in The Journal of biological chemistry (19.05.2000)
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