Quantitative determination of solid-state forms of a pharmaceutical development compound in drug substance and tablets
Xie, Yong, Tao, Wenle, Morrison, Henry, Chiu, Rick, Jona, Janan, Fang, Jan, Cauchon, Nina
Published in International journal of pharmaceutics (01.10.2008)
Published in International journal of pharmaceutics (01.10.2008)
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High-throughput 96-well solvent mediated sonic blending synthesis and on-plate solid/solution stability characterization of pharmaceutical cocrystals
Luu, Van, Jona, Janan, Stanton, Mary K., Peterson, Matthew L., Morrison, Henry G., Nagapudi, Karthik, Tan, Helming
Published in International journal of pharmaceutics (30.01.2013)
Published in International journal of pharmaceutics (30.01.2013)
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High-throughput logP measurement using parallel liquid chromatography/ultraviolet/mass spectrometry and sample-pooling
Zhao, Yining, Jona, Janan, Chow, David T., Rong, Haojing, Semin, David, Xia, Xiaoyang, Zanon, Roger, Spancake, Chris, Maliski, Ed
Published in Rapid communications in mass spectrometry (01.01.2002)
Published in Rapid communications in mass spectrometry (01.01.2002)
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Fast surface crystallization of amorphous griseofulvin below T g
Zhu, Lei, Jona, Janan, Nagapudi, Karthik, Wu, Tian
Published in Pharmaceutical research (01.08.2010)
Published in Pharmaceutical research (01.08.2010)
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DPC 681 and DPC 684: Potent, Selective Inhibitors of Human Immunodeficiency Virus Protease Active against Clinically Relevant Mutant Variants
KALTENBACH, Robert F, TRAINOR, George, KLABE, Ronald, DIAMOND, Sharon, DAVIES, Marc, SAYE, Joanne, JONA, Ianan, ERICKSON-VIITANEN, Susan, GETMAN, Daniel, HARRIS, Greg, GARBER, Sena, CORDOVA, Beverly, BACHELER, Lee, JEFFREY, Susan, LOGUE, Kelly, CAWOOD, Pamela
Published in Antimicrobial Agents and Chemotherapy (01.11.2001)
Published in Antimicrobial Agents and Chemotherapy (01.11.2001)
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Discovery of a Potent, Orally Active 11 beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (S)-2-(1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221
Veniant, Murielle M., Hale, Clarence, Hungate, Randall W., Gahm, Kyung, Emery, Maurice G., Jona, Janan, Joseph, Smriti, Adams, Jeffrey, Hague, Andrew, Moniz, George, Zhang, Jiandong, Bartberger, Michael D., Li, Vivian, Syed, Rashid, Jordan, Steven, Komorowski, Renee, Chen, Michelle M., Cupples, Rod, Kim, Ki Won, St Jean, David J., Johansson, Lars, Henriksson, Martin A., Williams, Meredith, Vallgarda, Jerk, Fotsch, Christopher, Wang, Minghan
Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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A Quantitative Kinetic Study of Polysorbate Autoxidation: The Role of Unsaturated Fatty Acid Ester Substituents
Yao, Jia, Dokuru, Dushyanth K., Noestheden, Matthew, Park, SungAe S., Kerwin, Bruce A., Jona, Janan, Ostovic, Drazen, Reid, Darren L.
Published in Pharmaceutical research (01.10.2009)
Published in Pharmaceutical research (01.10.2009)
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Manufacture and Performance Evaluation of a Stable Amorphous Complex of an Acidic Drug Molecule and Neusilin
Maclean, Jenifer, Medina, Cesar, Daurio, Dominick, Alvarez‐Nunez, Fernando, Jona, Janan, Munson, Eric, Nagapudi, Karthik
Published in Journal of pharmaceutical sciences (01.08.2011)
Published in Journal of pharmaceutical sciences (01.08.2011)
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Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)
Véniant, Murielle M, Hale, Clarence, Hungate, Randall W, Gahm, Kyung, Emery, Maurice G, Jona, Janan, Joseph, Smriti, Adams, Jeffrey, Hague, Andrew, Moniz, George, Zhang, Jiandong, Bartberger, Michael D, Li, Vivian, Syed, Rashid, Jordan, Steven, Komorowski, Renée, Chen, Michelle M, Cupples, Rod, Kim, Ki Won, St. Jean, David J, Johansson, Lars, Henriksson, Martin A, Williams, Meredith, Vallgårda, Jerk, Fotsch, Christopher, Wang, Minghan
Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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Multiple approaches to pharmaceutical polymorphism investigation--a case study
Li, Haitao, Kiang, Y-H, Jona, Janan
Published in European journal of pharmaceutical sciences (08.12.2009)
Published in European journal of pharmaceutical sciences (08.12.2009)
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Conformational Isomerism in Solid State of AMG 853—Structure Studies Using Solid-State Nuclear Magnetic Resonance and X-ray Diffraction
Kiang, Y.-H., Nagapudi, Karthik, Wu, Tian, Peterson, Matthew L., Jona, Janan, Staples, Richard J., Stephens, Peter W.
Published in Journal of pharmaceutical sciences (01.07.2015)
Published in Journal of pharmaceutical sciences (01.07.2015)
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Crystal structure, crystal morphology, and surface properties of an investigational drug
Kiang, Y.-H., Yang, Chia-Yi, Staples, Richard J., Jona, Janan
Published in International journal of pharmaceutics (23.02.2009)
Published in International journal of pharmaceutics (23.02.2009)
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Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency
Qian, Wenyuan, Chen, Jian Jeffrey, Human, Jason, Aya, Toshihiro, Zhu, Jiawang, Biswas, Kaustav, Peterkin, Tanya, Hungate, Randall W., Arik, Leyla, Johnson, Eileen, Kumar, Gondi, Joseph, Smriti, Jona, Janan, Guo, Hong-Xun, Wu, Zufan
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors
Buchanan, John L., Newcomb, John R., Carney, David P., Chaffee, Stuart C., Chai, Lilly, Cupples, Rod, Epstein, Linda F., Gallant, Paul, Gu, Yan, Harmange, Jean-Christophe, Hodge, Kathy, Houk, Brett E., Huang, Xin, Jona, Janan, Joseph, Smriti, Jun, H. Toni, Kumar, Rakesh, Li, Chun, Lu, John, Menges, Tom, Morrison, Michael J., Novak, Perry M., van der Plas, Simon, Radinsky, Robert, Rose, Paul E., Sawant, Satin, Sun, Ji-Rong, Surapaneni, Sekhar, Turci, Susan M., Xu, Keyang, Yanez, Evelyn, Zhao, Huilin, Zhu, Xiaotian
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation
Chen, Jian Jeffrey, Nguyen, Thomas, D’Amico, Derin C., Qian, Wenyuan, Human, Jason, Aya, Toshihiro, Biswas, Kaustav, Fotsch, Christopher, Han, Nianhe, Liu, Qingyian, Nishimura, Nobuko, Peterkin, Tanya A.N., Yang, Kevin, Zhu, Jiawang, Riahi, Babak Bobby, Hungate, Randall W., Andersen, Neil G., Colyer, John T., Faul, Margaret M., Kamassah, Augustus, Wang, Judy, Jona, Janan, Kumar, Gondi, Johnson, Eileen, Askew, Benny C.
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Preparation of 1-(3-aminobenzo[d]isoxazol-5-yl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective, and efficacious inhibitors of coagulation factor Xa
LI, Yun-Long, FEVIG, John M, WEXLER, Ruth R, LAM, Patrick Y. S, CACCIOLA, Joseph, BURIAK, Joseph, ROSSI, Karen A, JONA, Janan, KNABB, Robert M, LUETTGEN, Joseph M, WONG, Pancras C, BAI, Stephen A
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
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Quantification of compaction-induced crystallinity reduction of a pharmaceutical solid using 19F solid-state NMR and powder X-ray diffraction
Liu, Jodi, Nagapudi, Karthik, Kiang, Y-H, Martinez, Ezequiel, Jona, Janan
Published in Drug development and industrial pharmacy (01.08.2009)
Published in Drug development and industrial pharmacy (01.08.2009)
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