Search Results - "Jolly, Douglas" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma

by Cloughesy, Timothy F, Landolfi, Joseph, Hogan, Daniel J, Bloomfield, Stephen, Carter, Bob, Chen, Clark C, Elder, J Bradley, Kalkanis, Steven N, Kesari, Santosh, Lai, Albert, Lee, Ian Y, Liau, Linda M, Mikkelsen, Tom, Nghiemphu, Phioanh Leia, Piccioni, David, Walbert, Tobias, Chu, Alice, Das, Asha, Diago, Oscar R, Gammon, Dawn, Gruber, Harry E, Hanna, Michelle, Jolly, Douglas J, Kasahara, Noriyuki, McCarthy, David, Mitchell, Leah, Ostertag, Derek, Robbins, Joan M, Rodriguez-Aguirre, Maria, Vogelbaum, Michael A
Published in Science translational medicine (01.06.2016)

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Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC

Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC

by Cloughesy, Timothy F, Landolfi, Joseph, Vogelbaum, Michael A, Ostertag, Derek, Elder, James B, Bloomfield, Stephen, Carter, Bob, Chen, Clark C, Kalkanis, Steven N, Kesari, Santosh, Lai, Albert, Lee, Ian Y, Liau, Linda M, Mikkelsen, Tom, Nghiemphu, Phioanh, Piccioni, David, Accomando, William, Diago, Oscar R, Hogan, Daniel J, Gammon, Dawn, Kasahara, Noriyuki, Kheoh, Thian, Jolly, Douglas J, Gruber, Harry E, Das, Asha, Walbert, Tobias
Published in Neuro-oncology (Charlottesville, Va.) (03.09.2018)

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Retroviral Replicating Vector Toca 511 ( Vocimagene Amiretrorepvec ) for Prodrug Activator Gene Therapy of Lung Cancer

Retroviral Replicating Vector Toca 511 ( Vocimagene Amiretrorepvec ) for Prodrug Activator Gene Therapy of Lung Cancer

by Kushiya, Hiroki, Hiraoka, Kei, Suzuki, Tomohiro, Inoko, Kazuho, Inagaki, Akihito, Niwa, Hiroki, Sasaki, Katsunori, Nakamura, Toru, Tsuchikawa, Takahiro, Shichinohe, Toshiaki, Jolly, Douglas J, Kasahara, Noriyuki, Hirano, Satoshi
Published in Cancers (25.11.2022)

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Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model

by Mitchell, Leah A, Lopez Espinoza, Fernando, Mendoza, Daniel, Kato, Yuki, Inagaki, Akihito, Hiraoka, Kei, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J, Robbins, Joan M
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2017)

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Clinical development of retroviral replicating vector Toca 511 for gene therapy of cancer

Clinical development of retroviral replicating vector Toca 511 for gene therapy of cancer

by Collins, Sara A., Shah, Ashish H., Ostertag, Derek, Kasahara, Noriyuki, Jolly, Douglas J.
Published in Expert opinion on biological therapy (02.09.2021)

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Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model

Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model

by Niwa, Hiroki, Nakamura, Toru, Kushiya, Hiroki, Kuraya, Tomotaka, Inoko, Kazuho, Inagaki, Akihito, Suzuki, Tomohiro, Sasaki, Katsunori, Tsuchikawa, Takahiro, Hiraoka, Kei, Shichinohe, Toshiaki, Hatanaka, Yutaka, Jolly, Douglas J., Kasahara, Noriyuki, Hirano, Satoshi
Published in Cancer gene therapy (01.09.2024)

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Molecular Analyses Support the Safety and Activity of Retroviral Replicating Vector Toca 511 in Patients

Molecular Analyses Support the Safety and Activity of Retroviral Replicating Vector Toca 511 in Patients

by Hogan, Daniel J, Zhu, Jay-Jiguang, Diago, Oscar R, Gammon, Dawn, Haghighi, Ali, Lu, Guangrong, Das, Asha, Gruber, Harry E, Jolly, Douglas J, Ostertag, Derek
Published in Clinical cancer research (01.10.2018)

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Molecular and Immunologic Signatures are Related to Clinical Benefit from Treatment with Vocimagene Amiretrorepvec (Toca 511) and 5-Fluorocytosine (Toca FC) in Patients with Glioma

Molecular and Immunologic Signatures are Related to Clinical Benefit from Treatment with Vocimagene Amiretrorepvec (Toca 511) and 5-Fluorocytosine (Toca FC) in Patients with Glioma

by Accomando, William P, Rao, Aliz R, Hogan, Daniel J, Newman, Aaron M, Nakao, Aki, Alizadeh, Ash A, Diehn, Maximilian, Diago, Oscar R, Gammon, Dawn, Haghighi, Ali, Gruber, Harry E, Jolly, Douglas J, Ostertag, Derek
Published in Clinical cancer research (01.12.2020)

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Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

by Perez, Omar D, Logg, Christopher R, Hiraoka, Kei, Diago, Oscar, Burnett, Ryan, Inagaki, Akihito, Jolson, Dawn, Amundson, Karin, Buckley, Taylor, Lohse, Dan, Lin, Amy, Burrascano, Cindy, Ibanez, Carlos, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J
Published in Molecular therapy (01.09.2012)

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Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity

Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity

by Hiraoka, Kei, Inagaki, Akihito, Kato, Yuki, Huang, Tiffany T, Mitchell, Leah A, Kamijima, Shuichi, Takahashi, Masamichi, Matsumoto, Hiroshi, Hacke, Katrin, Kruse, Carol A, Ostertag, Derek, Robbins, Joan M, Gruber, Harry E, Jolly, Douglas J, Kasahara, Noriyuki
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2017)

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Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model

Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model

by Huang, Tiffany T, Parab, Shraddha, Burnett, Ryan, Diago, Oscar, Ostertag, Derek, Hofman, Florence M, Espinoza, Fernando Lopez, Martin, Bryan, Ibañez, Carlos E, Kasahara, Noriyuki, Gruber, Harry E, Pertschuk, Daniel, Jolly, Douglas J, Robbins, Joan M
Published in Human gene therapy (01.02.2015)

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Efficient Therapeutic Protein Expression Using Retroviral Replicating Vector with 2A Peptide in Cancer Models

Efficient Therapeutic Protein Expression Using Retroviral Replicating Vector with 2A Peptide in Cancer Models

by Hofacre, Andrew, Yagiz, Kader, Mendoza, Daniel, Lopez Espinoza, Fernando, Munday, Anthony W, Burrascano, Cynthia, Singer, Oded, Gruber, Harry E, Jolly, Douglas J, Lin, Amy H
Published in Human gene therapy (01.04.2018)

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Therapeutic activity of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer

Therapeutic activity of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer

by Inoko, Kazuho, Hiraoka, Kei, Inagaki, Akihito, Takahashi, Mizuna, Kushibiki, Toshihiro, Hontani, Koji, Takano, Hironobu, Sato, Shoki, Takeuchi, Shintaro, Nakamura, Toru, Tsuchikawa, Takahiro, Shichinohe, Toshiaki, Gruber, Harry E, Jolly, Douglas J, Kasahara, Noriyuki, Hirano, Satoshi
Published in Cancer gene therapy (01.08.2018)

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Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity

Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity

by Lin, Amy H, Burrascano, Cindy, Pettersson, Par L, Ibañez, Carlos E, Gruber, Harry E, Jolly, Douglas J
Published in Journal of virology (01.09.2014)

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Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector

Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector

by Ostertag, Derek, Amundson, Karin K, Lopez Espinoza, Fernando, Martin, Bryan, Buckley, Taylor, Galvão da Silva, Ana Paula, Lin, Amy H, Valenta, David T, Perez, Omar D, Ibañez, Carlos E, Chen, Ching-I, Pettersson, Pär L, Burnett, Ryan, Daublebsky, Veronika, Hlavaty, Juraj, Gunzburg, Walter, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J, Robbins, Joan M
Published in Neuro-oncology (Charlottesville, Va.) (01.02.2012)

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Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models

Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models

by Yagiz, Kader, Huang, Tiffany T, Lopez Espinoza, Fernando, Mendoza, Daniel, Ibañez, Carlos E, Gruber, Harry E, Jolly, Douglas J, Robbins, Joan M
Published in Neuro-oncology (Charlottesville, Va.) (01.10.2016)

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Abstract 1413: Treatment of mouse liver and brain colon cancer metastases with Toca 511 and 5-fluorocytosine for intratumoral production of 5-fluorouracil leads to increased survival, induction of antitumor immune responses, and reduction of MDSC

Abstract 1413: Treatment of mouse liver and brain colon cancer metastases with Toca 511 and 5-fluorocytosine for intratumoral production of 5-fluorouracil leads to increased survival, induction of antitumor immune responses, and reduction of MDSC

by Rodriguez-Aguirre, Maria, Yagiz, Kader, Lopez Espinoza, Fernando, Mendoza, Daniel, Huang, Tiffany T., Ibanez, Carlos, Gruber, Harry E., Jolly, Douglas J., Robbins, Joan
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro

Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro

by Lin, Amy H., Twitty, Christopher G., Burnett, Ryan, Hofacre, Andrew, Mitchell, Leah A., Espinoza, Fernando Lopez, Gruber, Harry E., Jolly, Douglas J.
Published in Molecular therapy. Nucleic acids (17.03.2017)

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Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-Fluorouracil-Mediated Cytotoxicity in Multiple Human Cancer Types

Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-Fluorouracil-Mediated Cytotoxicity in Multiple Human Cancer Types

by Twitty, Chris G, Diago, Oscar R, Hogan, Daniel J, Burrascano, Cindy, Ibanez, Carlos E, Jolly, Douglas J, Ostertag, Derek
Published in Human gene therapy. Part B. Methods (01.02.2016)

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Retroviral replicating vectors in cancer

Retroviral replicating vectors in cancer

by Logg, Christopher R, Robbins, Joan M, Jolly, Douglas J, Gruber, Harry E, Kasahara, Noriyuki
Published in Methods in enzymology (2012)

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