Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
HONORE, Prisca, KAGE, Karen, MIKUSA, Joseph, WATT, Andrew T, JOHNSTON, Joseph F, WYATT, Jacqueline R, FALTYNEK, Connie R, JARVIS, Michael F, LYNCH, Kevin
Published in Pain (Amsterdam) (01.09.2002)
Published in Pain (Amsterdam) (01.09.2002)
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Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
Monia, B P, Johnston, J F, Geiger, T, Muller, M, Fabbro, D
Published in Nature medicine (01.06.1996)
Published in Nature medicine (01.06.1996)
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Phase I Trial of ISIS 5132, an Antisense Oligonucleotide Inhibitor of c-raf-1, Administered by 24-hour Weekly Infusion to Patients with Advanced Cancer
RUDIN, Charles M, HOLMLUND, Jon, KWOH, T. Jesse, DORR, F. Andrew, RATAIN, Mark J, FLEMING, Gini F, MANI, Sridhar, STADLER, Walter M, SCHUMM, Philip, MONIA, Brett P, JOHNSTON, Joseph F, GEARY, Richard, YU, Rosie Z
Published in Clinical cancer research (01.05.2001)
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Published in Clinical cancer research (01.05.2001)
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Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo
Monia, Brett P., Sasmor, Henri, Johnston, Joseph F., Freier, Susan M., Lesnik, Elena A., Muller, Marcel, Geiger, Thomas, Altmann, Karl-Heinz, Moser, Heinz, Fabbro, Doriano
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.1996)
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A Phase I trial of h‐ras antisense oligonucleotide ISIS 2503 administered as a continuous intravenous infusion in patients with advanced carcinoma
Cunningham, C. Casey, Holmlund, Jon T., Geary, Richard S., Kwoh, T. Jesse, Dorr, Andrew, Johnston, Joseph F., Monia, Brett, Nemunaitis, John
Published in Cancer (01.09.2001)
Published in Cancer (01.09.2001)
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Nuclease Resistance and Antisense Activity of Modified Oligonucleotides Targeted to Ha-ras
Monia, B P, Johnston, J F, Sasmor, H, Cummins, L L
Published in The Journal of biological chemistry (14.06.1996)
Published in The Journal of biological chemistry (14.06.1996)
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Selective Inhibition of A-Raf and C-Raf mRNA Expression by Antisense Oligodeoxynucleotides in Rat Vascular Smooth Muscle Cells: Role of A-Raf and C-Raf in Serum-Induced Proliferation
Cioffi, C L, Garay, M, Johnston, J F, McGraw, K, Boggs, R T, Hreniuk, D, Monia, B P
Published in Molecular pharmacology (01.03.1997)
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Published in Molecular pharmacology (01.03.1997)
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In vitro and in vivo effects of an α3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide
Adams, Monique R., Nikkel, Arthur L., Donnelly-Roberts, Diana L., Watt, Andrew T., Johnston, Joseph F., Cowsert, Lex M., Butler, Mandeline, Kroeger, Paul E., Frost, Leigh, Curzon, Peter, Decker, Michael W., Bitner, Robert Scott
Published in Brain research. Molecular brain research. (22.10.2004)
Published in Brain research. Molecular brain research. (22.10.2004)
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Journal Article
Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
Honore, Prisca, Kage, Karen, Mikusa, Joseph, Watt, Andrew T, Johnston, Joseph F, Wyatt, Jacqueline R, Faltynek, Connie R, Jarvis, Michael F, Lynch, Kevin
Published in Pain (Amsterdam) (01.09.2002)
Published in Pain (Amsterdam) (01.09.2002)
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Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway
Schulte, Theodor W., Blagosklonny, Mikhail V., Romanova, Larissa, Mushinski, J. Frederic, Monia, Brett P., Johnston, Joseph F., Nguyen, Phuongmai, Trepel, Jane, Neckers, Leonard M.
Published in Molecular and Cellular Biology (01.10.1996)
Published in Molecular and Cellular Biology (01.10.1996)
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Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides
MONIA, B. P, JOHNSTON, J. F, ECKER, D. J, ZOUNES, M. A, LIMA, W. F, FREIER, S. M
Published in The Journal of biological chemistry (05.10.1992)
Published in The Journal of biological chemistry (05.10.1992)
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Biophysical and antisense properties of oligodeoxynucleotides containing 7-propynyl-, 7-iodo- and 7-cyano-7-deaza-2-amino-2′-deoxyadenosines
Balow, Guity, Mohan, Venkatraman, Lesnik, Elena A., Johnston, Joseph F., Monia, Brett P., Acevedo, Oscar L.
Published in Nucleic acids research (15.07.1998)
Published in Nucleic acids research (15.07.1998)
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Journal Article
Analgesic profile of intrathecal P2X 3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
Honore, Prisca, Kage, Karen, Mikusa, Joseph, Watt, Andrew T., Johnston, Joseph F., Wyatt, Jacqueline R., Faltynek, Connie R., Jarvis, Michael F., Lynch, Kevin
Published in Pain (Amsterdam) (2002)
Published in Pain (Amsterdam) (2002)
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Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats
Stepkowski, S M, Qu, X, Wang, M E, Tian, L, Chen, W, Wancewicz, E V, Johnston, J F, Bennett, C F, Monia, B P
Published in Transplantation (27.08.2000)
Published in Transplantation (27.08.2000)
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