A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection
Blume, Cornelia, Jackson, Claire L, Spalluto, Cosma Mirella, Legebeke, Jelmer, Nazlamova, Liliya, Conforti, Franco, Perotin, Jeanne-Marie, Frank, Martin, Butler, John, Crispin, Max, Coles, Janice, Thompson, James, Ridley, Robert A, Dean, Lareb S N, Loxham, Matthew, Reikine, Stephanie, Azim, Adnan, Tariq, Kamran, Johnston, David A, Skipp, Paul J, Djukanovic, Ratko, Baralle, Diana, McCormick, Christopher J, Davies, Donna E, Lucas, Jane S, Wheway, Gabrielle, Mennella, Vito
Published in Nature genetics (01.02.2021)
Published in Nature genetics (01.02.2021)
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Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α
Tezera, Liku B, Bielecka, Magdalena K, Ogongo, Paul, Walker, Naomi F, Ellis, Matthew, Garay-Baquero, Diana J, Thomas, Kristian, Reichmann, Michaela T, Johnston, David A, Wilkinson, Katalin Andrea, Ahmed, Mohamed, Jogai, Sanjay, Jayasinghe, Suwan N, Wilkinson, Robert J, Mansour, Salah, Thomas, Gareth J, Ottensmeier, Christian H, Leslie, Alasdair, Elkington, Paul T
Published in eLife (24.02.2020)
Published in eLife (24.02.2020)
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Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection
Beers, Stephen A., French, Ruth R., Chan, H.T. Claude, Lim, Sean H., Jarrett, Timothy C., Vidal, Regina Mora, Wijayaweera, Sahan S., Dixon, Sandra V., Kim, Hyungjin, Cox, Kerry L., Kerr, Jonathan P., Johnston, David A., Johnson, Peter W.M., Verbeek, J. Sjef, Glennie, Martin J., Cragg, Mark S.
Published in Blood (24.06.2010)
Published in Blood (24.06.2010)
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Journal Article
Collective Cell Behavior in Mechanosensing of Substrate Thickness
Tusan, Camelia G., Man, Yu-Hin, Zarkoob, Hoda, Johnston, David A., Andriotis, Orestis G., Thurner, Philipp J., Yang, Shoufeng, Sander, Edward A., Gentleman, Eileen, Sengers, Bram G., Evans, Nicholas D.
Published in Biophysical journal (05.06.2018)
Published in Biophysical journal (05.06.2018)
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Journal Article
Mouse early extra-embryonic lineages activate compensatory endocytosis in response to poor maternal nutrition
Sun, Congshan, Velazquez, Miguel A, Marfy-Smith, Stephanie, Sheth, Bhavwanti, Cox, Andy, Johnston, David A, Smyth, Neil, Fleming, Tom P
Published in Development (Cambridge) (01.03.2014)
Published in Development (Cambridge) (01.03.2014)
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Journal Article
Oxidative Stress and Dysfunctional Intracellular Traffic Linked to an Unhealthy Diet Results in Impaired Cargo Transport in the Retinal Pigment Epithelium (RPE)
Keeling, Eloise, Chatelet, David S., Johnston, David A., Page, Anton, Tumbarello, David A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Published in Molecular nutrition & food research (01.08.2019)
Published in Molecular nutrition & food research (01.08.2019)
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Journal Article
The Role of Cholesterol on Triterpenoid Saponin-Induced Endolysosomal Escape of a Saporin-Based Immunotoxin
Smith, Wendy S, Johnston, David A, Wensley, Harrison J, Holmes, Suzanne E, Flavell, Sopsamorn U, Flavell, David J
Published in International journal of molecular sciences (19.11.2020)
Published in International journal of molecular sciences (19.11.2020)
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An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy
Keeling, Eloise, Culling, Annabelle J, Johnston, David A, Chatelet, David S, Page, Anton, Tumbarello, David A, Lotery, Andrew J, Ratnayaka, J Arjuna
Published in International journal of molecular sciences (11.09.2020)
Published in International journal of molecular sciences (11.09.2020)
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Journal Article
Intracellular residency of Staphylococcus aureus within mast cells in nasal polyps: A novel observation
Hayes, Stephen M., MRCS, Howlin, Robert, PhD, Johnston, David A., PhD, Webb, Jeremy S., PhD, Clarke, Stuart C., FRCPath, FFPH, Stoodley, Paul, PhD, Harries, Philip G., FRCS (ORL-HNS), Wilson, Susan J., PhD, Pender, Sylvia L.F., PhD, Faust, Saul N., PhD, FRCPCH, Hall-Stoodley, Luanne, PhD, Salib, Rami J., PhD, FRCS (ORL-HNS)
Published in Journal of allergy and clinical immunology (01.06.2015)
Published in Journal of allergy and clinical immunology (01.06.2015)
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Journal Article
Peri‐arterial pathways for clearance of α‐Synuclein and tau from the brain: Implications for the pathogenesis of dementias and for immunotherapy
Nimmo, Jacqui, Johnston, David A., Dodart, J. C., MacGregor‐Sharp, Matthew T., Weller, Roy O., Nicoll, James A. R., Verma, Ajay, Carare, Roxana O.
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)
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Journal Article
Extraordinary host switching in siphonostomatoid copepods and the demise of the Monstrilloida: Integrating molecular data, ontogeny and antennulary morphology
Huys, Rony, Llewellyn-Hughes, Julia, Conroy-Dalton, Sophie, Olson, Peter D., Spinks, Jennifer N., Johnston, David A.
Published in Molecular phylogenetics and evolution (01.05.2007)
Published in Molecular phylogenetics and evolution (01.05.2007)
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Journal Article
TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity
Yu, Xiaojie, James, Sonya, Felce, James H, Kellermayer, Blanka, Johnston, David A, Chan, H T Claude, Penfold, Christine A, Kim, Jinny, Inzhelevskaya, Tatyana, Mockridge, C Ian, Watanabe, Yasunori, Crispin, Max, French, Ruth R, Duriez, Patrick J, Douglas, Leon R, Glennie, Martin J, Cragg, Mark S
Published in Communications biology (23.06.2021)
Published in Communications biology (23.06.2021)
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Journal Article
The complete mitochondrial genomes of Schistosoma haematobium and Schistosoma spindale and the evolutionary history of mitochondrial genome changes among parasitic flatworms
Littlewood, D. Timothy J., Lockyer, Anne E., Webster, Bonnie L., Johnston, David A., Le, Thanh Hoa
Published in Molecular phylogenetics and evolution (01.05.2006)
Published in Molecular phylogenetics and evolution (01.05.2006)
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Journal Article
Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents
Smith, Wendy S, Johnston, David A, Holmes, Suzanne E, Wensley, Harrison J, Flavell, Sopsamorn U, Flavell, David J
Published in Toxins (20.02.2019)
Published in Toxins (20.02.2019)
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Journal Article
Breast Cancer Risk for Noncarriers of Family-Specific BRCA1 and BRCA2 Mutations: Findings From the Breast Cancer Family Registry
KURIAN, Allison W, GONG, Gail D, OZCELIK, Hilmi, DITE, Gillian S, APICELLA, Carmel, SOUTHEY, Melissa C, WHITTEMORE, Alice S, JOHN, Esther M, JOHNSTON, David A, FELBERG, Anna, WEST, Dee W, MIRON, Alexander, ANDRULIS, Irene L, HOPPER, John L, KNIGHT, Julia A
Published in Journal of clinical oncology (01.12.2011)
Published in Journal of clinical oncology (01.12.2011)
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Journal Article
Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function
Lynn, Savannah A., Johnston, David A., Scott, Jenny A., Munday, Rosie, Desai, Roshni S., Keeling, Eloise, Weaterton, Ruaridh, Simpson, Alexander, Davis, Dillon, Freeman, Thomas, Chatelet, David S., Page, Anton, Cree, Angela J., Lee, Helena, Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Published in Cells (Basel, Switzerland) (17.02.2021)
Published in Cells (Basel, Switzerland) (17.02.2021)
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Journal Article
Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways
Albargothy, Nazira J., Johnston, David A., MacGregor-Sharp, Matthew, Weller, Roy O., Verma, Ajay, Hawkes, Cheryl A., Carare, Roxana O.
Published in Acta neuropathologica (01.07.2018)
Published in Acta neuropathologica (01.07.2018)
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