The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
Beer, Nicola L., Tribble, Nicholas D., McCulloch, Laura J., Roos, Charlotta, Johnson, Paul R.V., Orho-Melander, Marju, Gloyn, Anna L.
Published in Human molecular genetics (01.11.2009)
Published in Human molecular genetics (01.11.2009)
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Journal Article
Perlecan: An Islet Basement Membrane Protein with Protective Anti-Inflammatory Characteristics
Brandhorst, Daniel, Brandhorst, Heide, Acreman, Samuel, Johnson, Paul R V
Published in Bioengineering (Basel) (01.08.2024)
Published in Bioengineering (Basel) (01.08.2024)
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Journal Article
long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation
Cnop, M, Hughes, S. J, Igoillo-Esteve, M, Hoppa, M. B, Sayyed, F, van de Laar, L, Gunter, J. H, de Koning, E. J. P, Walls, G. V, Gray, D. W. G, Johnson, P. R. V, Hansen, B. C, Morris, J. F, Pipeleers-Marichal, M, Cnop, I, Clark, A
Published in Diabetologia (01.02.2010)
Published in Diabetologia (01.02.2010)
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Journal Article
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
Walker, J. N., Ramracheya, R., Zhang, Q., Johnson, P. R. V., Braun, M., Rorsman, P.
Published in Diabetes, obesity & metabolism (01.10.2011)
Published in Diabetes, obesity & metabolism (01.10.2011)
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Journal Article
The effects of TAK-875, a selective G protein-coupled receptor 40/free fatty acid 1 agonist, on insulin and glucagon secretion in isolated rat and human islets
Yashiro, Hiroaki, Tsujihata, Yoshiyuki, Takeuchi, Koji, Hazama, Masatoshi, Johnson, Paul R V, Rorsman, Patrik
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
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Journal Article
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
MacDonald, Patrick E, De Marinis, Yang Zhang, Ramracheya, Reshma, Salehi, Albert, Ma, Xiaosong, Johnson, Paul R V, Cox, Roger, Eliasson, Lena, Rorsman, Patrik
Published in PLoS biology (01.06.2007)
Published in PLoS biology (01.06.2007)
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Journal Article
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
Shigeto, Makoto, Ramracheya, Reshma, Tarasov, Andrei I, Cha, Chae Young, Chibalina, Margarita V, Hastoy, Benoit, Philippaert, Koenraad, Reinbothe, Thomas, Rorsman, Nils, Salehi, Albert, Sones, William R, Vergari, Elisa, Weston, Cathryn, Gorelik, Julia, Katsura, Masashi, Nikolaev, Viacheslav O, Vennekens, Rudi, Zaccolo, Manuela, Galione, Antony, Johnson, Paul R V, Kaku, Kohei, Ladds, Graham, Rorsman, Patrik
Published in The Journal of clinical investigation (01.12.2015)
Published in The Journal of clinical investigation (01.12.2015)
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Journal Article
Factors influencing the collagenase digestion phase of human islet isolation
Kin, Tatsuya, Johnson, Paul R V, Shapiro, A M James, Lakey, Jonathan R T
Published in Transplantation (01.01.2007)
Published in Transplantation (01.01.2007)
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Journal Article
GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion
Gandasi, Nikhil R., Gao, Rui, Kothegala, Lakshmi, Pearce, Abigail, Santos, Cristiano, Acreman, Samuel, Basco, Davide, Benrick, Anna, Chibalina, Margarita V., Clark, Anne, Guida, Claudia, Harris, Matthew, Johnson, Paul R. V., Knudsen, Jakob G., Ma, Jinfang, Miranda, Caroline, Shigeto, Makoto, Tarasov, Andrei I., Yeung, Ho Yan, Thorens, Bernard, Asterholm, Ingrid W., Zhang, Quan, Ramracheya, Reshma, Ladds, Graham, Rorsman, Patrik
Published in Diabetologia (01.03.2024)
Published in Diabetologia (01.03.2024)
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Journal Article
Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
ROSENGREN, Anders H, BRAUN, Matthias, EDLUND, Anna, GRAM PEDERSEN, Morten, JONSSON, Anna, RAMRACHEYA, Reshma, YUNZHAO TANG, WALKER, Jonathan N, BARRETT, Amy, JOHNSON, Paul R. V, LYSSENKO, Valeriya, MCCARTHY, Mark I, MAHDI, Taman, GROOP, Leif, SALEHI, Albert, GLOYN, Anna L, RENSTRÖM, Erik, RORSMAN, Patrik, ELIASSON, Lena, ANDERSSON, Sofia A, TRAVERS, Mary E, SHIGETO, Makoto, ZHANG, Enming, ALMGREN, Peter, LADENVALL, Claes, AXELSSON, Annika S
Published in Diabetes (New York, N.Y.) (01.07.2012)
Published in Diabetes (New York, N.Y.) (01.07.2012)
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Journal Article
Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity
Brandhorst, Heide, Johnson, Paul R. V., Korsgren, Olle, Brandhorst, Daniel
Published in Cell transplantation (01.11.2017)
Published in Cell transplantation (01.11.2017)
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Journal Article
Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs
Cross, S. E, Richards, S. K, Clark, A, Benest, A. V, Bates, D. O, Mathieson, P. W, Johnson, P. R. V, Harper, S. J, Smith, R. M
Published in Diabetologia (01.07.2007)
Published in Diabetologia (01.07.2007)
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Journal Article
Contemporary management and outcomes for infants born with oesophageal atresia
Burge, D. M., Shah, K., Spark, P., Shenker, N., Pierce, M., Kurinczuk, J. J., Draper, E. S., Johnson, P. R. V., Knight, M.
Published in British journal of surgery (01.03.2013)
Published in British journal of surgery (01.03.2013)
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Journal Article
Monitoring real-time hormone release kinetics via high-content 3-D imaging of compensatory endocytosis
Tarasov, Andrei I, Galvanovskis, Juris, Rorsman, Olof, Hamilton, Alexander, Vergari, Elisa, Johnson, Paul R V, Reimann, Frank, Ashcroft, Frances M, Rorsman, Patrik
Published in Lab on a chip (11.09.2018)
Published in Lab on a chip (11.09.2018)
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Journal Article
Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation
Brandhorst, Daniel, Parnaud, Géraldine, Friberg, Andrew, Lavallard, Vanessa, Demuylder-Mischler, Sandrine, Hughes, Stephen, Saphörster, Julia, Kurfürst, Manfred, Korsgren, Olle, Berney, Thierry, Johnson, Paul R. V.
Published in Cell transplantation (01.10.2017)
Published in Cell transplantation (01.10.2017)
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Journal Article
Responses of marine benthic microalgae to elevated CO2
Johnson, V. R., Brownlee, C., Rickaby, R. E. M., Graziano, M., Milazzo, M., Hall-Spencer, J. M.
Published in Marine biology (01.08.2013)
Published in Marine biology (01.08.2013)
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