A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models
Zhou, Yiming, Castonguay, Philip, Sidhom, Eriene-Heidi, Clark, Abbe R., Dvela-Levitt, Moran, Kim, Sookyung, Sieber, Jonas, Wieder, Nicolas, Jung, Ji Yong, Andreeva, Svetlana, Reichardt, Jana, Dubois, Frank, Hoffmann, Sigrid C., Basgen, John M., Montesinos, Mónica S., Weins, Astrid, Johnson, Ashley C., Lander, Eric S., Garrett, Michael R., Hopkins, Corey R., Greka, Anna
Published in Science (American Association for the Advancement of Science) (08.12.2017)
Published in Science (American Association for the Advancement of Science) (08.12.2017)
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Journal Article
Single cell RNA sequencing reveals ferritin as a key mediator of autoimmune pre-disposition in a mouse model of systemic lupus erythematosus
Younes, Subhi Talal, Showmaker, Kurt, Johnson, Ashley C, Garrett, Michael R, Ryan, Michael J
Published in Scientific reports (20.12.2021)
Published in Scientific reports (20.12.2021)
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Journal Article
Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model
Keele, Gregory R, Prokop, Jeremy W, He, Hong, Holl, Katie, Littrell, John, Deal, Aaron W, Kim, Yunjung, Kyle, Patrick B, Attipoe, Esinam, Johnson, Ashley C, Uhl, Katie L, Sirpilla, Olivia L, Jahanbakhsh, Seyedehameneh, Robinson, Melanie, Levy, Shawn, Valdar, William, Garrett, Michael R, Solberg Woods, Leah C
Published in Scientific reports (22.01.2021)
Published in Scientific reports (22.01.2021)
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Journal Article
Allelic Variants in Arhgef11 via the Rho-Rock Pathway Are Linked to Epithelial-Mesenchymal Transition and Contributes to Kidney Injury in the Dahl Salt-Sensitive Rat
Jia, Zhen, Johnson, Ashley C, Wang, Xuexiang, Guo, Zibiao, Dreisbach, Albert W, Lewin, Jack R, Kyle, Patrick B, Garrett, Michael R
Published in PloS one (14.07.2015)
Published in PloS one (14.07.2015)
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Journal Article
Nitric oxide and oxidative stress pathways do not contribute to sex differences in renal injury and function in Dahl SS/Jr rats
Turbeville, Hannah R., Johnson, Ashley C., Garrett, Michael R., Dent, Elena L., Sasser, Jennifer M.
Published in Physiological reports (01.07.2020)
Published in Physiological reports (01.07.2020)
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Journal Article
Nephron-deficient HSRA rats exhibit renal injury with age but have limited renal damage from streptozotocin-induced hyperglycemia
Cobb, Meredith B, Wu, Wenjie, Attipoe, Esinam M, Johnson, Ashley C, Garrett, Michael R
Published in American journal of physiology. Renal physiology (01.06.2021)
Published in American journal of physiology. Renal physiology (01.06.2021)
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Journal Article
Loss of Arhgef11 in the Dahl Salt-Sensitive Rat Protects Against Hypertension-Induced Renal Injury
Johnson, Ashley C, Wu, Wenjie, Attipoe, Esinam M, Sasser, Jennifer M, Taylor, Erin B, Showmaker, Kurt C, Kyle, Patrick B, Lindsey, Merry L, Garrett, Michael R
Published in Hypertension (Dallas, Tex. 1979) (01.04.2020)
Published in Hypertension (Dallas, Tex. 1979) (01.04.2020)
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Journal Article
Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats
McPherson, Kasi C, Shields, Corbin A, Poudel, Bibek, Johnson, Ashley C, Taylor, Lateia, Stubbs, Cassandra, Nichols, Alyssa, Cornelius, Denise C, Garrett, Michael R, Williams, Jan M
Published in American journal of physiology. Renal physiology (01.04.2020)
Published in American journal of physiology. Renal physiology (01.04.2020)
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Journal Article
Loss of Cingulin-like 1 in Dahl Salt-Sensitive Rats Leads to Reduced Renal Injury and Blood Pressure
Attipoe, Esinam M, Wu, Wenjie, Johnson, Ashley C, Chandran, Agata C, Cobb, Meredith B, Milner, Andrew, Kota, Kamal, Garrett, Noah R, Crisler, Marshea K, Showmaker, Kurt C, Garrett, Michael R
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Journal Article
Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats
McPherson, Kasi C, Taylor, Lateia, Johnson, Ashley C, Didion, Sean P, Geurts, Aron M, Garrett, Michael R, Williams, Jan M
Published in American journal of physiology. Renal physiology (01.10.2016)
Published in American journal of physiology. Renal physiology (01.10.2016)
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Journal Article
Nephron Deficiency and Predisposition to Renal Injury in a Novel One-Kidney Genetic Model
Wang, Xuexiang, Johnson, Ashley C, Williams, Jan M, White, Tiffani, Chade, Alejandro R, Zhang, Jie, Liu, Ruisheng, Roman, Richard J, Lee, Jonathan W, Kyle, Patrick B, Solberg-Woods, Leah, Garrett, Michael R
Published in Journal of the American Society of Nephrology (01.07.2015)
Published in Journal of the American Society of Nephrology (01.07.2015)
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Journal Article
Genetic susceptibility and loss of Nr4a1 enhances macrophage-mediated renal injury in CKD
Westbrook, Lindsey, Johnson, Ashley C, Regner, Kevin R, Williams, Jan M, Mattson, David L, Kyle, Patrick B, Henegar, Jeffery R, Garrett, Michael R
Published in Journal of the American Society of Nephrology (01.11.2014)
Published in Journal of the American Society of Nephrology (01.11.2014)
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Journal Article
Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart
Jones, David K, Johnson, Ashley C, Roti Roti, Elon C, Liu, Fang, Uelmen, Rebecca, Ayers, Rebecca A, Baczko, Istvan, Tester, David J, Ackerman, Michael J, Trudeau, Matthew C, Robertson, Gail A
Published in Journal of cell science (15.03.2018)
Published in Journal of cell science (15.03.2018)
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Journal Article
Estimation of Nephron Number in Whole Kidney using the Acid Maceration Method
Peterson, Sarah M, Wang, Xuexiang, Johnson, Ashley C, Coate, Ian D, Garrett, Michael R, Didion, Sean P
Published in Journal of visualized experiments (22.05.2019)
Published in Journal of visualized experiments (22.05.2019)
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Journal Article
Spontaneous one-kidney rats are more susceptible to develop hypertension by DOCA-NaCl and subsequent kidney injury compared with uninephrectomized rats
Wang, Xuexiang, Johnson, Ashley C, Sasser, Jennifer M, Williams, Jan M, Solberg Woods, Leah C, Garrett, Michael R
Published in American journal of physiology. Renal physiology (15.05.2016)
Published in American journal of physiology. Renal physiology (15.05.2016)
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Journal Article
Genetic Variants in Arhgef11 Are Associated With Kidney Injury in the Dahl Salt-Sensitive Rat
Williams, Jan M, Johnson, Ashley C, Stelloh, Cary, Dreisbach, Albert W, Franceschini, Nora, Regner, Kevin R, Townsend, Raymond R, Roman, Richard J, Garrett, Michael R
Published in Hypertension (Dallas, Tex. 1979) (01.11.2012)
Published in Hypertension (Dallas, Tex. 1979) (01.11.2012)
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