Bleeding Events and Safety Outcomes in Patients with Hemophilia a with Inhibitors: A Prospective, Multicenter, Non-Interventional Study
Mahlangu, Johnny, Oldenburg, Johannes, Callaghan, Michael U, Shima, Midori, Santagostino, Elena, Lehle, Michaela, Uguen, Marianne, Hirst, Ceri, Moore, Maggie, Recht, Michael, Garcia, Claudia, Yang, Renchi, Kruse-Jarres, Rebecca
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Cover Image
Escobar, Miguel, Castaman, Giancarlo, Boix, Santiago Bonanad, Callaghan, Michael, Moerloose, Philippe, Ducore, Jonathan, Hermans, Cédric, Journeycake, Janna, Leissinger, Cindy, Luck, James, Mahlangu, Johnny, Miesbach, Wolfgang, Mitha, Ismail Haroon, Négrier, Claude, Quon, Doris, Recht, Michael, Schved, Jean François, Shapiro, Amy D., Sidonio, Robert, Srivastava, Alok, Stasyshyn, Oleksandra, Vilchevska, Kateryna V., Wang, Michael, Young, Guy, Alexander, W. Allan, Al‐Sabbagh, Ahmad, Bonzo, Daniel, Macie, Christopher, Wilkinson, Thomas A., Kessler, Craig
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2021)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2021)
Get full text
Journal Article
Efficacy of emicizumab is maintained throughout dosing intervals for bleed prophylaxis
Pipe, Steven W., Trzaskoma, Ben, Minhas, Miranda, Lehle, Michaela, Ko, Richard H., Gao, Ling, Mahlangu, Johnny, Kempton, Christine L., Kessler, Craig M., Kruse-Jarres, Rebecca
Published in Research and practice in thrombosis and haemostasis (01.02.2023)
Published in Research and practice in thrombosis and haemostasis (01.02.2023)
Get full text
Journal Article
Endogenous factor VIII synthesis from the intron 22–inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A
Pandey, Gouri Shankar, Yanover, Chen, Miller-Jenkins, Lisa M, Garfield, Susan, Cole, Shelley A, Curran, Joanne E, Moses, Eric K, Rydz, Natalia, Simhadri, Vijaya, Kimchi-Sarfaty, Chava, Lillicrap, David, Viel, Kevin R, Przytycka, Teresa M, Pierce, Glenn F, Howard, Tom E, Sauna, Zuben E
Published in Nature medicine (01.10.2013)
Published in Nature medicine (01.10.2013)
Get full text
Journal Article
Real-World Rates of Bleeding, Factor VIII Use, and Quality of Life in Individuals with Severe Haemophilia A Receiving Prophylaxis in a Prospective, Noninterventional Study
Kenet, Gili, Chen, Yeu-Chin, Lowe, Gillian, Percy, Charles, Tran, Huyen, von Drygalski, Annette, Trossaërt, Marc, Reding, Mark, Oldenburg, Johannes, Mingot-Castellano, Maria Eva, Park, Young-Shil, Peyvandi, Flora, Ozelo, Margareth C, Mahlangu, Johnny, Quinn, Jennifer, Huang, Mei, Reddy, Divya B, Kim, Benjamin
Published in Journal of clinical medicine (18.12.2021)
Published in Journal of clinical medicine (18.12.2021)
Get full text
Journal Article
Switching from Sucrose-Formulated rFVIII to Octocog Alfa (BAY 81-8973) Prophylaxis Improves Bleed Outcomes in the LEOPOLD Clinical Trials
Kenet, Gili, Moulton, Thomas, Wicklund, Brian M, Ahuja, Sanjay P, Escobar, Miguel, Mahlangu, Johnny
Published in Journal of blood medicine (01.01.2023)
Published in Journal of blood medicine (01.01.2023)
Get full text
Journal Article
Corrigendum to ‘Efficacy of emicizumab is maintained throughout dosing intervals for bleed prophylaxis’ [Research and Practice in Thrombosis and Haemostasis, Volume 7, Issue 2, February 2023, 100077]
Pipe, Steven W., Trzaskoma, Ben, Minhas, Miranda, Lehle, Michaela, Ko, Richard H., Gao, Ling, Mahlangu, Johnny, Kempton, Christine L., Kessler, Craig M., Kruse-Jarres, Rebecca
Published in Research and practice in thrombosis and haemostasis (01.05.2023)
Published in Research and practice in thrombosis and haemostasis (01.05.2023)
Get full text
Journal Article
Efficacy and safety of a VWF/FVIII concentrate (wilate®) in inherited von Willebrand disease patients undergoing surgical procedures
Srivastava, A., Serban, M., Werner, S., Schwartz, B. A., Kessler, C. M., Alkindi, Salam, Apte, Shashikant Janardan, Castaman, Giancarlo, Gill, Joan Cox, Hellmann, Andrzej, Kavakli, Kaan, Kouides, Peter A., Kuriakose, Philip, Lissitchkov, Toshko, Ma, Alice, Mahlangu, Johnny, Morfini, Massimo, Neufeld, Ellis J., Peyvandi, Flora, Reding, Mark, Rodriguez, Nidra I., Ross, Cecil, Rusen, Luminita, Shapiro, Amy, Uscatescu, Valentina, Windyga, Jerzy, Zulfikar, Bulent
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.03.2017)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.03.2017)
Get full text
Journal Article
Pharmacokinetics and coagulation biomarkers in children and adults with hemophilia A receiving emicizumab prophylaxis every 1, 2, or 4 weeks
Kiialainen, Anna, Adamkewicz, Joanne I., Petry, Claire, Oldenburg, Johannes, Pipe, Steven W., Young, Guy, Mahlangu, Johnny, Lehle, Michaela, Niggli, Markus, Castaman, Giancarlo, Jiménez-Yuste, Víctor, Shima, Midori, Négrier, Claude, Schmitt, Christophe
Published in Research and practice in thrombosis and haemostasis (01.01.2024)
Published in Research and practice in thrombosis and haemostasis (01.01.2024)
Get full text
Journal Article
Predicting FVIII Activity in Patients Who Use Recombinant FVIII Fc Fusion Protein for Prophylaxis and Treatment of Bleeding Episodes
Quon, Doris V., Mahlangu, Johnny N., Shapiro, Amy D, Pasi, John, Zhu, Ying, Pierce, Glenn F, Li, Lian, Allen, Geoffrey
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
Get full text
Journal Article
The TRUST Trial: Anti-Drug Antibody Formation In a Patient With Hemophilia With Inhibitors After Receiving The Activated Factor VII Product Bay 86-6150
Mahlangu, Johnny N., Koh, Pei Lin, Ng, Heng Joo, Lissitchkov, Toshko, Hardtke, Marion, Schroeder, Jens
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Perioperative Management of Hemostasis with Recombinant FIX Fc Fusion Protein in Subjects Undergoing Surgery in the B-YOND Study
Ozelo, Margareth Castro, Mahlangu, Johnny, Chan, Godfrey, Holmstrom, Margareta, Novitzky, Nicolas, Perry, David J, Yuan, Huixing, Cristiano, Lynda M, Mei, Baisong
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Rviii-Singlechain in Surgical Prophylaxis: Efficacy and Safety of Continuous and Bolus Infusion
Djambas Khayat, Claudia, Mahlangu, Johnny N., Baker, Ross I, Leissinger, Cindy A., Santagostino, Elena, Bensen-Kennedy, Debra M., St. Ledger, Katie, Veldman, Alex, Pabinger, Ingrid
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Uptake of Genetic Counseling, Knowledge of Bleeding risks and Psychosocial Impact in a South African Cohort of Female Relatives of People with Hemophilia
Gillham, Anne, Greyling, Brenda, Wessels, Tina-Marie, Mbele, Bongi, Schwyzer, Rosemarie, Krause, Amanda, Mahlangu, Johnny
Published in Journal of genetic counseling (01.12.2015)
Published in Journal of genetic counseling (01.12.2015)
Get full text
Journal Article
Longitudinal Analysis of Long-Term Safety and Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIFc) in Adults/Adolescents with Severe Hemophilia a
Konkle, Barbara, Pasi, K John, Perry, David J, Mahlangu, Johnny, Rangarajan, Savita, Brown, Simon A, Hanabusa, Hideji, Pabinger, Ingrid, Cristiano, Lynda M, Tsao, Elisa, Winding, Bent, Glazebrook, Desilu, Lethagen, Stefan, Jackson, Shannon
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Characterization of Bleeding in Hemophilia Carriers and Comparison to Women with Type 1 Von Willebrand Disease, Type 3 Von Willebrand Disease Obligate Carriers and Controls
Satkunam, Natasha Amrita, Mahlangu, Johnny, Bidlingmaier, Christoph, Mingot-Castellano, Maria Eva, Chitlur, Meera B., Fogarty, Patrick F., Cuker, Adam, Mancuso, Maria Elisa, Holme, Pal André, Grabell, Julie, Hopman, Wilma, Mathew, Prasad, James, Paula D.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Clinical Outcomes in Adults/Adolescents with Hemophilia B Treated Long Term with Recombinant Factor IX Fc Fusion Protein (rFIXFc) Prophylaxis: Interim Results of the B-Yond Extension Study
Matsushita, Tadashi, Mahlangu, Johnny, Shapiro, Amy D, Pasi, K John, Ragni, Margaret V., Ozelo, Margareth C, Oldenburg, Johannes, Baker, Ross I, Yuan, Huixing, Ramirez-Santiago, Alejandra, Ferrante, Francesca, Lethagen, Stefan
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Prophylaxis with a recombinant factor VIII Fc in hemophilia A: long-term follow-up on joint health, efficacy, and safety from phase 3 studies in children and adults
Konkle, Barbara A., Oldenburg, Johannes, Pasi, John, Kulkarni, Roshni, Nolan, Beatrice, Mahlangu, Johnny, Young, Guy, Brown, Simon A., Pabinger, Ingrid, Shapiro, Amy, Négrier, Claude, Blanchette, Victor, Ragni, Margaret V., Dumont, Jennifer, Lethagen, Stefan
Published in Research and practice in thrombosis and haemostasis (01.08.2023)
Published in Research and practice in thrombosis and haemostasis (01.08.2023)
Get full text
Journal Article
Post hoc longitudinal assessment of the efficacy and safety of recombinant factor IX Fc fusion protein in hemophilia B
Shapiro, Amy D., Kulkarni, Roshni, Ragni, Margaret V., Chambost, Hervé, Mahlangu, Johnny, Oldenburg, Johannes, Nolan, Beatrice, Ozelo, Margareth C., Foster, Meredith C., Willemze, Annemieke, Barnowski, Christopher, Jain, Nisha, Winding, Bent, Dumont, Jennifer, Lethagen, Stefan, Barnes, Chris, Pasi, K. John
Published in Blood advances (11.07.2023)
Published in Blood advances (11.07.2023)
Get full text
Journal Article
Plain language summary of the GENEr8-1 clinical trial of valoctocogene roxaparvovec gene therapy for hemophilia A
Lowe, Gillian, Fletcher, Simon, Lynch, Patrick James, Mahlangu, Johnny, Ozelo, Margareth C, Pembroke, Luke, Pipe, Steven W, Yamaguti-Hayakawa, Gabriela G, York, Deon, Robinson, Tara M, Yu, Hua, Valentino, Leonard A
Published in Future Rare Diseases (01.12.2023)
Published in Future Rare Diseases (01.12.2023)
Get full text
Journal Article