Abstract DDT02-03: Discovery of GDC-0994, a potent and selective ERK1/2 inhibitor in early clinical development
Robarge, Kirk, Schwarz, Jacob, Blake, Jim, Burkard, Michael, Chan, Jocelyn, Chen, Huifen, Chou, Kang-Jye, Diaz, Dolores, Gaudino, John, Gould, Stephen, Grina, Jonas, Linghu, Xin, Liu, Lichuan, Martinson, Matthew, Moreno, David A., Orr, Christine, Pacheco, Patricia, Qin, Ann, Rasor, Kevin, Ren, Li, Shahidi-Latham, Sheerin, Stults, Jeffrey, Sullivan, Francis, Wang, Weiru, Yin, Peter, Zhou, Aihe, Belvin, Marcia, Merchant, Mark, Moffat, John G.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
4,6-SUBSTITUTED-PYRAZOLO[1,5-A]PYRAZINES AS JANUS KINASE INHIBITORS
LAURENCE E BURGESS, RONALD JAY HINKLIN, ERIK JAMES HICKEN, MARK J CHICARELLI, RAJ K RAHEJA, JED PHENEGER, SATO YOSHITAKA, JOHN P FISCHER, KATERINA LEFTHERIS, ALLEN SHELLEY, JAY BRADFORD FELL, JOHN E ROBINSON, CHRISTOPHER F KRASER, ROBERT ANDREW RIEGER, JOHN GAUDINO, LAIRD ELLEN, MARK LAURENCE BOYS, TONY P TANG, BRYDON L BENNETT
Year of Publication 09.04.2020
Get full text
Year of Publication 09.04.2020
Patent
Preclinical stereoselective disposition and toxicokinetics of two novel MET inhibitors
Liederer, Bianca M., Liu, Xingrong, Berezhkovskiy, Leonid M., Cain, Gary, Ding, Xiao, Gaudino, John, Kaus, Robert, Plise, Emile G., Sutherlin, Daniel P., Harstad, Eric B.
Published in Xenobiotica (01.05.2012)
Published in Xenobiotica (01.05.2012)
Get full text
Journal Article
SERINE/THREONINE KINASE INHIBITORS
MARK JOSEPH CHICARELLI, LI REN, JOHN GAUDINO, RUSTAM FERDINAND GARREY, JAMES F BLAKE, JONAS GRINA, PETER J MOHR, CHEN HUIFEN, DAVID A MORENO, ZHOU AIHE, JACOB SCHWARZ, KIRK ROBARGE
Year of Publication 18.02.2016
Get full text
Year of Publication 18.02.2016
Patent
Solid phase synthesis of 1,4-benzodiazepine-2,5-diones
Mayer, John P., Zhang, Jingwen, Bjergarde, Kirsten, Lenz, Doug M., Gaudino, John J.
Published in Tetrahedron letters (04.11.1996)
Published in Tetrahedron letters (04.11.1996)
Get full text
Journal Article
Synthesis of spirolactams and spiropiperidines as CCR4 receptor antagonists
Hansen, Joshua D., Newhouse, Bradley J., Allen, Shelley, Anderson, Aaron, Eary, Todd, Schiro, Justin, Gaudino, John, Laird, Ellen, Allen, Andrew C., Chantry, David, Eberhardt, Christine, Burgess, Laurence E.
Published in Tetrahedron letters (02.01.2006)
Published in Tetrahedron letters (02.01.2006)
Get full text
Journal Article
PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John, MCNULTY, Oren T
Year of Publication 15.11.2023
Get full text
Year of Publication 15.11.2023
Patent
PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John, MCNULTY, Oren T
Year of Publication 02.11.2023
Get full text
Year of Publication 02.11.2023
Patent
Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET kinases
Barbour, Patrick, Dahlke, Joshua, Zhao, Qian, Allen, Shelley, McNulty, Oren T, Cook, Adam, Laird, Ellen, Hinklin, Ronald Jay, Gaudino, John
Year of Publication 10.10.2023
Get full text
Year of Publication 10.10.2023
Patent
PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
BARBOUR, PATRICK, HINKLIN, RONALD JAY, GAUDINO, JOHN, LAIRD, ELLEN, MCNULTY, OREN T, ALLEN, SHELLEY, DAHLKE, JOSHUA, COOK, ADAM, ZHAO, QIAN
Year of Publication 03.10.2023
Get full text
Year of Publication 03.10.2023
Patent
Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET Kinases
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, NULTY, Oren T, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John
Year of Publication 03.08.2023
Get full text
Year of Publication 03.08.2023
Patent
PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
Cook, Adam Wade, Doerner Barbour, Patrick Michael, Zhao, Qian, Gaudino, John Joseph, Laird, Ellen Ruth, Allen, Shelley, Dahlke, Joshua Ryan, Hinklin, Ronald Jay, McNulty, Oren Teague
Year of Publication 30.05.2024
Get full text
Year of Publication 30.05.2024
Patent
HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, GAUDINO, John Joseph, BOYS, Mark Laurence
Year of Publication 18.04.2024
Get full text
Year of Publication 18.04.2024
Patent
PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
Barbour, Patrick, Dahlke, Joshua, Zhao, Qian, Allen, Shelley, McNulty, Oren T, Cook, Adam, Laird, Ellen, Hinklin, Ronald Jay, Gaudino, John
Year of Publication 12.01.2023
Get full text
Year of Publication 12.01.2023
Patent
ERK PROTEIN KINASE INHIBITORS
SMITH, Alexandra Nicole, HINKLIN, Ronald Jay, BETTENDORF, Tanna Marie, MCNULTY, Oren Teague, WICKERSHAM, Kyle Adam, BACKOS, Donald Sanford, POLITES, Viktor Christian, COOK, Adam Wade, MORENO, David Austin, GAUDINO, John Joseph, KAHN, Dean Russell
Year of Publication 24.10.2024
Get full text
Year of Publication 24.10.2024
Patent
PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John, MCNULTY, Oren T
Year of Publication 22.09.2022
Get full text
Year of Publication 22.09.2022
Patent
Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET Kinases
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, NULTY, Oren T, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John
Year of Publication 26.05.2022
Get full text
Year of Publication 26.05.2022
Patent
Pyrazolo(3,4-b)pyridine compounds as inhibitors of TAM and MET Kinases
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John, MCNULTY, Oren T
Year of Publication 26.05.2022
Get full text
Year of Publication 26.05.2022
Patent
HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, GAUDINO, John Joseph, BOYS, Mark Laurence
Year of Publication 26.01.2023
Get full text
Year of Publication 26.01.2023
Patent