Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles
Zhou, Amber S, Tucker, John B, Scribano, Christina M, Lynch, Andrew R, Carlsen, Caleb L, Pop-Vicas, Sophia T, Pattaswamy, Srishrika M, Burkard, Mark E, Weaver, Beth A
Published in PLoS biology (26.10.2023)
Published in PLoS biology (26.10.2023)
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Journal Article
The Adenomatous Polyposis Coli Protein Unambiguously Localizes to Microtubule Plus Ends and Is Involved in Establishing Parallel Arrays of Microtubule Bundles in Highly Polarized Epithelial Cells
Mogensen, Mette M., Tucker, John B., Mackie, John B., Prescott, Alan R., Näthke, Inke S.
Published in The Journal of cell biology (10.06.2002)
Published in The Journal of cell biology (10.06.2002)
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Journal Article
CENP-E Inhibition Induces Chromosomal Instability and Synergizes with Diverse Microtubule-Targeting Agents in Breast Cancer
Tucker, John B, Carlsen, Caleb L, Scribano, Christina M, Pattaswamy, Srishrika M, Burkard, Mark E, Weaver, Beth A
Published in Cancer research (Chicago, Ill.) (15.08.2024)
Published in Cancer research (Chicago, Ill.) (15.08.2024)
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Journal Article
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel
Scribano, Christina M, Wan, Jun, Esbona, Karla, Tucker, John B, Lasek, Amber, Zhou, Amber S, Zasadil, Lauren M, Molini, Ryan, Fitzgerald, Jonathan, Lager, Angela M, Laffin, Jennifer J, Correia-Staudt, Kayla, Wisinski, Kari B, Tevaarwerk, Amye J, O'Regan, Ruth, McGregor, Stephanie M, Fowler, Amy M, Chappell, Richard J, Bugni, Tim S, Burkard, Mark E, Weaver, Beth A
Published in Science translational medicine (08.09.2021)
Published in Science translational medicine (08.09.2021)
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Journal Article
Chromosome Missegregation as a Modulator of Radiation Sensitivity
Cosper, Pippa F., Copeland, Sarah E., Tucker, John B., Weaver, Beth A.
Published in Seminars in radiation oncology (01.01.2022)
Published in Seminars in radiation oncology (01.01.2022)
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Journal Article
Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer
Hu, Yang, Manasrah, Baraa K, McGregor, Stephanie M, Lera, Robert F, Norman, Roshan X, Tucker, John B, Scribano, Christina M, Yan, Rachel E, Humayun, Mouhita, Wisinski, Kari B, Tevaarwerk, Amye J, O'Regan, Ruth M, Wilke, Lee G, Weaver, Beth A, Beebe, David J, Jin, Ning, Burkard, Mark E
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Journal Article
High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer
Jansson, Keith H., Tucker, John B., Stahl, Lauren E., Simmons, John K., Fuller, Caitlyn, Beshiri, Michael L., Agarwal, Supreet, Fang, Lei, Hynes, Paul G., Alilin, Aian Neil, Lake, Ross, Abbey, Yasmine C., Cawley, Jacob, Tice, Caitlin M., Yin, JuanJuan, McKnight, Crystal, Klummp-Thomas, Carleen, Zhang, Xiaohu, Guha, Rajarshi, Hoover, Shelley, Simpson, R. Mark, Nguyen, Holly M., Corey, Eva, Thomas, Craig J., Proia, David A., Kelly, Kathleen
Published in Scientific reports (22.11.2018)
Published in Scientific reports (22.11.2018)
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Journal Article
Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Tucker, John B, Bonema, Sarah C, García-Varela, Rebeca, Denu, Ryan A, Hu, Yang, McGregor, Stephanie M, Burkard, Mark E, Weaver, Beth A
Published in Cancer research communications (01.01.2023)
Published in Cancer research communications (01.01.2023)
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Journal Article
Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles
Amber S. Zhou, John B. Tucker, Christina M. Scribano, Andrew R. Lynch, Caleb L. Carlsen, Sophia T. Pop-Vicas, Srishrika M. Pattaswamy, Mark E. Burkard, Beth A. Weaver
Published in PLoS biology (01.10.2023)
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Published in PLoS biology (01.10.2023)
Journal Article
Abstract 2248: Paclitaxel-induced micronucleation activates pro-inflammatory cGAS/STING signaling in triple negative breast cancer
Hu, Yang, Jin, Ning, Manasrah, Baraa K., McGregor, Stephanie M., Scribano, Christina, Tucker, John B., Yan, Rachel, Lera, Robert F., Weaver, Beth A., Burkard, Mark E.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract B018: A high-throughput screen identifies HSP90 inhibitors as potent therapeutics across multiple clinically representative organoid models of advanced prostate cancer
Jansson, Keith H., Tucker, John B., Stahl, Lauren E., Simmons, John K., Fuller, Caitlyn, Beshiri, Michael L., Agarwal, Supreet, Abbey, Yasmine, Fang, Lei, Hynes, Paul G., Neil, Alilin Aian, Cawley, Jacob, Lake, Ross, Tran, Crystal, Tice, Caitlin M., Yin, JuanJuan, Zhang, Xiahu, Guha, Rajarshi, Hoover, Shelley, Simpson, R. Mark, Nguyen, Holly, Corey, Eva, Thomas, Craig J., Proia, David, Kelly, Kathleen
Published in Cancer research (Chicago, Ill.) (15.08.2018)
Published in Cancer research (Chicago, Ill.) (15.08.2018)
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Journal Article
Non-centrosomal microtubule-organising centres in cold-treated cultured Drosophila cells
Cottam, Deborah M, Tucker, John B, Rogers-Bald, Margaret M, Mackie, John B, Macintyre, John, Scarborough, Julie A, Ohkura, Hiroyuki, Milner, Martin J
Published in Cell motility and the cytoskeleton (01.02.2006)
Published in Cell motility and the cytoskeleton (01.02.2006)
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Positioning and capture of cell surface-associated microtubules in epithelial tendon cells that differentiate in primary embryonic Drosophila cell cultures
Tucker, John B, Mackie, John B, Cottam, Deborah M, Rogers-Bald, Margaret M, Macintyre, John, Scarborough, Julie A, Milner, Martin J
Published in Cell motility and the cytoskeleton (01.03.2004)
Published in Cell motility and the cytoskeleton (01.03.2004)
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Journal Article
The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly
Mogensen, Mette M, Tucker, John B, Mackie, John B, Prescott, Alan R, Nathke, Inke S
Published in The Journal of cell biology (10.06.2002)
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Published in The Journal of cell biology (10.06.2002)
Journal Article
Nucleation and capture of large cell surface‐associated microtubule arrays that are not located near centrosomes in certain cochlear epithelial cells
TUCKER, JOHN B., MOGENSEN, METTE M., HENDERSON, CRAIG G., DOXSEY, STEPHEN J., WRIGHT, MICHEL, STEARNS, TIM
Published in Journal of anatomy (01.01.1998)
Published in Journal of anatomy (01.01.1998)
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Journal Article
Three microtubule-organizing centres collaborate in a mouse cochlear epithelial cell during supracellularly coordinated control of microtubule positioning
Henderson, C G, Tucker, J B, Mogensen, M M, Mackie, J B, Chaplin, M A, Slepecky, N B, Leckie, L M
Published in Journal of cell science (01.01.1995)
Published in Journal of cell science (01.01.1995)
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Journal Article
Formation of two microtubule-nucleating sites which perform differently during centrosomal reorganization in a mouse cochlear epithelial cell
Tucker, J B, Mogensen, M M, Paton, C C, Mackie, J B, Henderson, C G, Leckie, L M
Published in Journal of cell science (01.04.1995)
Published in Journal of cell science (01.04.1995)
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Journal Article
Reorganization of the centrosome and associated microtubules during the morphogenesis of a mouse cochlear epithelial cell
HENDERSON, C. G, TUCKER, J. B, CHAPLIN, M. A, MACKIE, J. B, MAIDMENT, S. N, MOGENSEN, M. M, PATON, C. C
Published in Journal of cell science (01.02.1994)
Published in Journal of cell science (01.02.1994)
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