Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4—The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)
St. John, Sarah E., Tomar, Sakshi, Stauffer, Shaun R., Mesecar, Andrew D.
Published in Bioorganic & medicinal chemistry (01.09.2015)
Published in Bioorganic & medicinal chemistry (01.09.2015)
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Journal Article
Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS
Tomar, Sakshi, Johnston, Melanie L, St John, Sarah E, Osswald, Heather L, Nyalapatla, Prasanth R, Paul, Lake N, Ghosh, Arun K, Denison, Mark R, Mesecar, Andrew D
Published in The Journal of biological chemistry (07.08.2015)
Published in The Journal of biological chemistry (07.08.2015)
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Journal Article
X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus
St. John, Sarah E., Anson, Brandon J., Mesecar, Andrew D.
Published in Scientific reports (13.05.2016)
Published in Scientific reports (13.05.2016)
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Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2
St. John, Sarah E., Jensen, Katherine C., Kang, SooSung, Chen, Yafang, Calamini, Barbara, Mesecar, Andrew D., Lipton, Mark A.
Published in Bioorganic & medicinal chemistry (01.10.2013)
Published in Bioorganic & medicinal chemistry (01.10.2013)
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Journal Article
X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design
St. John, Sarah E., Therkelsen, Matthew D., Nyalapatla, Prasanth R., Osswald, Heather L., Ghosh, Arun K., Mesecar, Andrew D.
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
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Exploring the Relationship Between Treatment Satisfaction, Perceived Improvements in Functioning and Well-Being and Gambling Harm Reduction Among Clients of Pathological Gambling Treatment Programs
Monnat, Shannon M., Bernhard, Bo, Abarbanel, Brett L. L., John, Sarah St, Kalina, Ashlee
Published in Community mental health journal (01.08.2014)
Published in Community mental health journal (01.08.2014)
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Journal Article
Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance
Deng, Xufang, StJohn, Sarah E, Osswald, Heather L, O'Brien, Amornrat, Banach, Bridget S, Sleeman, Katrina, Ghosh, Arun K, Mesecar, Andrew D, Baker, Susan C
Published in Journal of virology (01.10.2014)
Published in Journal of virology (01.10.2014)
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Journal Article
Friendships Across Sexual Orientations: Experiences of Bisexual Women in Early Adulthood
Galupo, M. Paz, Sailer, Carin A., John, Sarah Causey St
Published in Journal of bisexuality (01.07.2004)
Published in Journal of bisexuality (01.07.2004)
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Journal Article
A structure-guided taxonomicbased approach to the design of broad-spectrum coronavirus protease inhibitors
Mesecar, Andrew D., St John, Sarah E., Lendy, Emma K., Anson, Brandon J., Chapman, Mackenzie E., Ghosh, Arun K.
Published in Acta crystallographica. Section A, Foundations and advances (14.08.2021)
Published in Acta crystallographica. Section A, Foundations and advances (14.08.2021)
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Journal Article
Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4—The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)
St. John, Sarah E., Tomar, Sakshi, Stauffer, Shaun R., Mesecar, Andrew D.
Published in Bioorganic & medicinal chemistry (01.09.2015)
Get full text
Published in Bioorganic & medicinal chemistry (01.09.2015)
Journal Article
X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design
St. John, Sarah E., Therkelsen, Matthew D., Nyalapatla, Prasanth R., Osswald, Heather L., Ghosh, Arun K., Mesecar, Andrew D.
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
Get full text
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
Journal Article
Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro)
Tomar, Sakshi, Johnston, Melanie L., St. John, Sarah E., Osswald, Heather L., Nyalapatla, Prasanth R., Paul, Lake N., Ghosh, Arun K., Denison, Mark R., Mesecar, Andrew D.
Published in The Journal of biological chemistry (07.08.2015)
Published in The Journal of biological chemistry (07.08.2015)
Get full text
Journal Article
A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses
Deng, Xufang, Agnihothram, Sudhakar, Mielech, Anna M, Nichols, Daniel B, Wilson, Michael W, StJohn, Sarah E, Larsen, Scott D, Mesecar, Andrew D, Lenschow, Deborah J, Baric, Ralph S, Baker, Susan C
Published in Journal of virology (01.10.2014)
Published in Journal of virology (01.10.2014)
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Journal Article
A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses
Deng, Xufang, Agnihothram, Sudhakar, Mielech, Anna M, Nichols, Daniel B, Wilson, Michael W, StJohn, Sarah E, Larsen, Scott D, Mesecar, Andrew D, Lenschow, Deborah J, Baric, Ralph S, Baker, Susan C
Published in Journal of virology (01.10.2014)
Published in Journal of virology (01.10.2014)
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Journal Article