Stereochemistry and molecular pharmacology of ( S)-thio-ATPA, a new potent and selective GluR5 agonist
Stensbøl, Tine B., Jensen, Henrik S., Nielsen, Birgitte, Johansen, Tommy N., Egebjerg, Jan, Frydenvang, Karla, Krogsgaard-Larsen, Povl
Published in European journal of pharmacology (12.01.2001)
Published in European journal of pharmacology (12.01.2001)
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The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors
Jensen, Anders A, Mosbacher, Johannes, Elg, Susanne, Lingenhoehl, Kurt, Lohmann, Tania, Johansen, Tommy N, Abrahamsen, Bjarke, Mattsson, Jan P, Lehmann, Anders, Bettler, Bernhard, Bräuner-Osborne, Hans
Published in Molecular pharmacology (01.06.2002)
Published in Molecular pharmacology (01.06.2002)
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Convergent Synthesis and Pharmacology of Substituted Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid Analogues
Vogensen, Stine B, Clausen, Rasmus P, Greenwood, Jeremy R, Johansen, Tommy N, Pickering, Darryl S, Nielsen, Birgitte, Ebert, Bjarke, Krogsgaard-Larsen, Povl
Published in Journal of medicinal chemistry (05.05.2005)
Published in Journal of medicinal chemistry (05.05.2005)
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(S)-Homo-AMPA, a specific agonist at the mGlu(6) subtype of metabotropic glutamic acid receptors
Ahmadian, H, Nielsen, B, Brauner-Osborne, H, Johansen, TN, Stensbol, TB, Slok, FA, Sekiyama, N, Nakanishi, S, KrogsgaardLarsen, P, Madsen, U
Published in Journal of medicinal chemistry (24.10.1997)
Published in Journal of medicinal chemistry (24.10.1997)
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A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors
Vogensen, SB, Greenwood, Varming, AR, Brehm, L, Pickering, DS, Nielsen, B, Liljefors, T, Clausen, RP, Johansen, TN, Krogsgaard-Larsen, P
Published in Organic & biomolecular chemistry (21.01.2004)
Published in Organic & biomolecular chemistry (21.01.2004)
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2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: Resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors
JOHANSEN, Tommy N, JANIN, Yves L, NIELSEN, Birgitte, FRYDENVANG, Karla, BRÄUNER-OSBORNE, Hans, STENSBØL, Tine B, VOGENSEN, Stine B, MADSEN, Ulf, KROGSGAARD-LARSEN, Povl
Published in Bioorganic & medicinal chemistry (01.07.2002)
Published in Bioorganic & medicinal chemistry (01.07.2002)
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Multiple Conformations of an Intercalated (−)-(7 S ,8 R ,9 S ,10 R )-N 6 -[10-(7,8,9,10-Tetrahydrobenzo[a]pyrenyl)]-2‘-deoxyadenosyl Adduct in the N-ras Codon 61 Sequence
Zegar, Irene S., Chary, Parvathi, Jabil, Ritche J., Tamura, Pamela J., Johansen, Tommy N., Lloyd, R. Stephen, Harris, Constance M., Harris, Thomas M., Stone, Michael P.
Published in Biochemistry (Easton) (24.11.1998)
Published in Biochemistry (Easton) (24.11.1998)
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Synthesis and Pharmacology of the Baclofen Homologues 5-Amino-4-(4-chlorophenyl)pentanoic Acid and the R- and S-Enantiomers of 5-Amino-3-(4-chlorophenyl)pentanoic Acid
Karla, Rolf, Ebert, Bjarke, Thorkildsen, Christian, Herdeis, Claus, Johansen, Tommy N, Nielsen, Birgitte, Krogsgaard-Larsen, Povl
Published in Journal of medicinal chemistry (03.06.1999)
Published in Journal of medicinal chemistry (03.06.1999)
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Heteroaryl Analogues of AMPA. 2. Synthesis, Absolute Stereochemistry, Photochemistry, and Structure−Activity Relationships
Falch, Erik, Brehm, Lotte, Mikkelsen, Ivan, Johansen, Tommy N, Skjærbæk, Niels, Nielsen, Birgitte, Stensbøl, Tine B, Ebert, Bjarke, Krogsgaard-Larsen, Povl
Published in Journal of medicinal chemistry (02.07.1998)
Published in Journal of medicinal chemistry (02.07.1998)
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Synthesis and Pharmacology of 3-Isoxazolol Amino Acids as Selective Antagonists at Group I Metabotropic Glutamic Acid Receptors
Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla, Hvene, Lise, Johansen, Tommy N, Nielsen, Birgitte, Sánchez, Connie, Stensbøl, Tine B, Bischoff, Francois, Krogsgaard-Larsen, Povl
Published in Journal of medicinal chemistry (29.03.2001)
Published in Journal of medicinal chemistry (29.03.2001)
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Excitatory Amino Acid Receptor Ligands: Resolution, Absolute Stereochemistry, and Enantiopharmacology of 2-Amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic Acid
Johansen, Tommy N, Ebert, Bjarke, Bräuner-Osborne, Hans, Didriksen, Michael, Christensen, Inge T, Søby, Karina K, Madsen, Ulf, Krogsgaard-Larsen, Povl, Brehm, Lotte
Published in Journal of medicinal chemistry (12.03.1998)
Published in Journal of medicinal chemistry (12.03.1998)
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Design of excitatory amino acid receptor agonists, partial agonists and antagonists: ibotenic acid as a key lead structure
Krogsgaard-Larsen, P, Ebert, B, Lund, TM, Bräuner-Osborne, H, Sløk, FA, Johansen, TN, Brehm, L, Madsen, U
Published in European journal of medicinal chemistry (1996)
Published in European journal of medicinal chemistry (1996)
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3-Pyrazolone analogues of the 3-isoxazolol metabotropic excitatory amino acid receptor agonist homo-AMPA. Synthesis and pharmacological testing
Zimmermann, Diane, Janin, Yves Louis, Brehm, Lotte, Bräuner-Osborne, Hans, Ebert, Bjarke, Johansen, Tommy Nørskov, Madsen, Ulf, Krogsgaard-Larsen, Povl
Published in European journal of medicinal chemistry (01.11.1999)
Published in European journal of medicinal chemistry (01.11.1999)
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