Common Molecular Pathways in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Weishaupt, Jochen H, Hyman, Tony, Dikic, Ivan
Published in Trends in molecular medicine (01.09.2016)
Published in Trends in molecular medicine (01.09.2016)
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Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis
Verde, Federico, Steinacker, Petra, Weishaupt, Jochen H, Kassubek, Jan, Oeckl, Patrick, Halbgebauer, Steffen, Tumani, Hayrettin, von Arnim, Christine A F, Dorst, Johannes, Feneberg, Emily, Mayer, Benjamin, Müller, Hans-Peter, Gorges, Martin, Rosenbohm, Angela, Volk, Alexander E, Silani, Vincenzo, Ludolph, Albert C, Otto, Markus
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2019)
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2019)
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TDP-43 is intercellularly transmitted across axon terminals
Feiler, Marisa S, Strobel, Benjamin, Freischmidt, Axel, Helferich, Anika M, Kappel, Julia, Brewer, Bryson M, Li, Deyu, Thal, Dietmar R, Walther, Paul, Ludolph, Albert C, Danzer, Karin M, Weishaupt, Jochen H
Published in The Journal of cell biology (23.11.2015)
Published in The Journal of cell biology (23.11.2015)
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Effect of High‐Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis
Ludolph, Albert C., Dorst, Johannes, Dreyhaupt, Jens, Weishaupt, Jochen H., Kassubek, Jan, Weiland, Ulrike, Meyer, Thomas, Petri, Susanne, Hermann, Andreas, Emmer, Alexander, Grosskreutz, Julian, Grehl, Torsten, Zeller, Daniel, Boentert, Matthias, Schrank, Bertold, Prudlo, Johannes, Winkler, Andrea S., Gorbulev, Stanislav, Roselli, Francesco, Schuster, Joachim, Dupuis, Luc
Published in Annals of neurology (01.02.2020)
Published in Annals of neurology (01.02.2020)
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Neurofilament levels as biomarkers in asymptomatic and symptomatic familial amyotrophic lateral sclerosis
Weydt, Patrick, Oeckl, Patrick, Huss, André, Müller, Kathrin, Volk, Alexander E., Kuhle, Jens, Knehr, Antje, Andersen, Peter M., Prudlo, Johannes, Steinacker, Petra, Weishaupt, Jochen H., Ludolph, Albert C., Otto, Markus
Published in Annals of neurology (01.01.2016)
Published in Annals of neurology (01.01.2016)
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Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
Naumann, Marcel, Pal, Arun, Goswami, Anand, Lojewski, Xenia, Japtok, Julia, Vehlow, Anne, Naujock, Maximilian, Günther, René, Jin, Mengmeng, Stanslowsky, Nancy, Reinhardt, Peter, Sterneckert, Jared, Frickenhaus, Marie, Pan-Montojo, Francisco, Storkebaum, Erik, Poser, Ina, Freischmidt, Axel, Weishaupt, Jochen H, Holzmann, Karlheinz, Troost, Dirk, Ludolph, Albert C, Boeckers, Tobias M, Liebau, Stefan, Petri, Susanne, Cordes, Nils, Hyman, Anthony A, Wegner, Florian, Grill, Stephan W, Weis, Joachim, Storch, Alexander, Hermann, Andreas
Published in Nature communications (23.01.2018)
Published in Nature communications (23.01.2018)
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Multicenter evaluation of neurofilaments in early symptom onset amyotrophic lateral sclerosis
Feneberg, Emily, Oeckl, Patrick, Steinacker, Petra, Verde, Federico, Barro, Christian, Van Damme, Philip, Gray, Elizabeth, Grosskreutz, Julian, Jardel, Claude, Kuhle, Jens, Koerner, Sonja, Lamari, Foudil, Amador, Maria Del Mar, Mayer, Benjamin, Morelli, Claudia, Muckova, Petra, Petri, Susanne, Poesen, Koen, Raaphorst, Joost, Salachas, François, Silani, Vincenzo, Stubendorff, Beatrice, Turner, Martin R, Verbeek, Marcel M, Weishaupt, Jochen H, Weydt, Patrick, Ludolph, Albert C, Otto, Markus
Published in Neurology (02.01.2018)
Published in Neurology (02.01.2018)
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Journal Article
Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients
Grozdanov, Veselin, Bliederhaeuser, Corinna, Ruf, Wolfgang P., Roth, Valerie, Fundel-Clemens, Kathrin, Zondler, Lisa, Brenner, David, Martin-Villalba, Ana, Hengerer, Bastian, Kassubek, Jan, Ludolph, Albert C., Weishaupt, Jochen H., Danzer, Karin M.
Published in Acta neuropathologica (01.11.2014)
Published in Acta neuropathologica (01.11.2014)
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Stress induced TDP-43 mobility loss independent of stress granules
Streit, Lisa, Kuhn, Timo, Vomhof, Thomas, Bopp, Verena, Ludolph, Albert C., Weishaupt, Jochen H., Gebhardt, J. Christof M., Michaelis, Jens, Danzer, Karin M.
Published in Nature communications (19.09.2022)
Published in Nature communications (19.09.2022)
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Comprehensive analysis of the mutation spectrum in 301 German ALS families
Müller, Kathrin, Brenner, David, Weydt, Patrick, Meyer, Thomas, Grehl, Torsten, Petri, Susanne, Grosskreutz, Julian, Schuster, Joachim, Volk, Alexander E, Borck, Guntram, Kubisch, Christian, Klopstock, Thomas, Zeller, Daniel, Jablonka, Sibylle, Sendtner, Michael, Klebe, Stephan, Knehr, Antje, Günther, Kornelia, Weis, Joachim, Claeys, Kristl G, Schrank, Berthold, Sperfeld, Anne-Dorte, Hübers, Annemarie, Otto, Markus, Dorst, Johannes, Meitinger, Thomas, Strom, Tim M, Andersen, Peter M, Ludolph, Albert C, Weishaupt, Jochen H
Published in Journal of neurology, neurosurgery and psychiatry (01.08.2018)
Published in Journal of neurology, neurosurgery and psychiatry (01.08.2018)
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Proteasome impairment by α-synuclein
Zondler, Lisa, Kostka, Marcus, Garidel, Patrick, Heinzelmann, Udo, Hengerer, Bastian, Mayer, Benjamin, Weishaupt, Jochen H, Gillardon, Frank, Danzer, Karin M
Published in PloS one (25.09.2017)
Published in PloS one (25.09.2017)
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Peripheral monocytes are functionally altered and invade the CNS in ALS patients
Zondler, Lisa, Müller, Kathrin, Khalaji, Samira, Bliederhäuser, Corinna, Ruf, Wolfgang P., Grozdanov, Veselin, Thiemann, Meinolf, Fundel-Clemes, Katrin, Freischmidt, Axel, Holzmann, Karlheinz, Strobel, Benjamin, Weydt, Patrick, Witting, Anke, Thal, Dietmar R., Helferich, Anika M., Hengerer, Bastian, Gottschalk, Kay-Eberhard, Hill, Oliver, Kluge, Michael, Ludolph, Albert C., Danzer, Karin M., Weishaupt, Jochen H.
Published in Acta neuropathologica (01.09.2016)
Published in Acta neuropathologica (01.09.2016)
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Journal Article
Effect of high-caloric nutrition on serum neurofilament light chain levels in amyotrophic lateral sclerosis
Dorst, Johannes, Schuster, Joachim, Dreyhaupt, Jens, Witzel, Simon, Weishaupt, Jochen H, Kassubek, Jan, Weiland, Ulrike, Petri, Susanne, Meyer, Thomas, Grehl, Torsten, Hermann, Andreas, Jordan, Berit, Grosskreutz, Julian, Zeller, Daniel, Boentert, Matthias, Schrank, Bertold, Prudlo, Johannes, Winkler, Andrea S, Gorbulev, Stanislav, Roselli, Franceso, Dupuis, Luc, Otto, Markus, Ludolph, Albert C
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2020)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2020)
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Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation
Catanese, Alberto, Olde Heuvel, Florian, Mulaw, Medhanie, Demestre, Maria, Higelin, Julia, Barbi, Gotthold, Freischmidt, Axel, Weishaupt, Jochen H., Ludolph, Albert C., Roselli, Francesco, Boeckers, Tobias M.
Published in Autophagy (03.10.2019)
Published in Autophagy (03.10.2019)
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Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice
Brenner, David, Sieverding, Kirsten, Bruno, Clara, Lüningschrör, Patrick, Buck, Eva, Mungwa, Simon, Fischer, Lena, Brockmann, Sarah J, Ulmer, Johannes, Bliederhäuser, Corinna, Philibert, Clémentine E, Satoh, Takashi, Akira, Shizuo, Boillée, Séverine, Mayer, Benjamin, Sendtner, Michael, Ludolph, Albert C, Danzer, Karin M, Lobsiger, Christian S, Freischmidt, Axel, Weishaupt, Jochen H
Published in The Journal of experimental medicine (04.02.2019)
Published in The Journal of experimental medicine (04.02.2019)
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Journal Article
Poly‐GP in cerebrospinal fluid links C9orf72‐associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD
Lehmer, Carina, Oeckl, Patrick, Weishaupt, Jochen H, Volk, Alexander E, Diehl‐Schmid, Janine, Schroeter, Matthias L, Lauer, Martin, Kornhuber, Johannes, Levin, Johannes, Fassbender, Klaus, Landwehrmeyer, Bernhard, Schludi, Martin H, Arzberger, Thomas, Kremmer, Elisabeth, Flatley, Andrew, Feederle, Regina, Steinacker, Petra, Weydt, Patrick, Ludolph, Albert C, Edbauer, Dieter, Otto, Markus, Danek, Adrian, Feneberg, Emily, Anderl‐Straub, Sarah, Arnim, Christine, Jahn, Holger, Schneider, Anja, Maler, Manuel, Polyakova, Maryna, Riedl, Lina, Wiltfang, Jens, Ziegler, Georg
Published in EMBO molecular medicine (01.07.2017)
Published in EMBO molecular medicine (01.07.2017)
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De novo FUS mutations are the most frequent genetic cause in early-onset German ALS patients
Hübers, Annemarie, Just, Walter, Rosenbohm, Angela, Müller, Kathrin, Marroquin, Nicolai, Goebel, Ingrid, Högel, Josef, Thiele, Holger, Altmüller, Janine, Nürnberg, Peter, Weishaupt, Jochen H, Kubisch, Christian, Ludolph, Albert C, Volk, Alexander E
Published in Neurobiology of aging (01.11.2015)
Published in Neurobiology of aging (01.11.2015)
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Low T-cell reactivity to TDP-43 peptides in ALS
Ramachandran, Swetha, Grozdanov, Veselin, Leins, Bianca, Kandler, Katharina, Witzel, Simon, Mulaw, Medhanie, Ludolph, Albert C, Weishaupt, Jochen H, Danzer, Karin M
Published in Frontiers in immunology (21.07.2023)
Published in Frontiers in immunology (21.07.2023)
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