A G-quadruplex-binding macrodomain within the “SARS-unique domain” is essential for the activity of the SARS-coronavirus replication–transcription complex
Kusov, Yuri, Tan, Jinzhi, Alvarez, Enrique, Enjuanes, Luis, Hilgenfeld, Rolf
Published in Virology (New York, N.Y.) (01.10.2015)
Published in Virology (New York, N.Y.) (01.10.2015)
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Journal Article
3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses
Tan, Jinzhi, George, Shyla, Kusov, Yuri, Perbandt, Markus, Anemüller, Stefan, Mesters, Jeroen R, Norder, Helene, Coutard, Bruno, Lacroix, Céline, Leyssen, Pieter, Neyts, Johan, Hilgenfeld, Rolf
Published in Journal of Virology (01.04.2013)
Published in Journal of Virology (01.04.2013)
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Journal Article
The SARS-unique domain (SUD) of SARS coronavirus contains two macrodomains that bind G-quadruplexes
Tan, Jinzhi, Vonrhein, Clemens, Smart, Oliver S, Bricogne, Gerard, Bollati, Michela, Kusov, Yuri, Hansen, Guido, Mesters, Jeroen R, Schmidt, Christian L, Hilgenfeld, Rolf
Published in PLoS pathogens (01.05.2009)
Published in PLoS pathogens (01.05.2009)
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Journal Article
Picornavirus non-structural proteins as targets for new anti-virals with broad activity
Norder, Heléne, De Palma, Armando M., Selisko, Barbara, Costenaro, Lionel, Papageorgiou, Nicolas, Arnan, Carme, Coutard, Bruno, Lantez, Violaine, De Lamballerie, Xavier, Baronti, Cécile, Solà, Maria, Tan, Jinzhi, Neyts, Johan, Canard, Bruno, Coll, Miquel, Gorbalenya, Alexander E., Hilgenfeld, Rolf
Published in Antiviral research (01.03.2011)
Published in Antiviral research (01.03.2011)
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Journal Article
Synthesis and antitumor evaluation of novel 5-substituted-4-hydroxy-8-nitroquinazolines as EGFR signaling-targeted inhibitors
Jin, Yi, Li, Hui-Yuan, Lin, Li-Ping, Tan, Jinzhi, Ding, Jian, Luo, Xiaomin, Long, Ya-Qiu
Published in Bioorganic & medicinal chemistry (01.10.2005)
Published in Bioorganic & medicinal chemistry (01.10.2005)
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Journal Article
Structure-based identification of small molecule compounds targeting cell cyclophilin A with anti-HIV-1 activity
Chen, Shuai, Zhao, Xuemei, Tan, Jinzhi, Lu, Hong, Qi, Zhi, Huang, Qiang, Zeng, Xianzhuo, Zhang, Mingjun, Jiang, Shibo, Jiang, Hualiang, Yu, Long
Published in European journal of pharmacology (22.06.2007)
Published in European journal of pharmacology (22.06.2007)
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Journal Article
Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin
Shi, Yan-hong, Song, Yan-Li, Lin, Dong-hai, Tan, Jinzhi, Roller, Peter P., Li, Qian, Long, Ya-Qiu, Song, Guo-Qiang
Published in Biochemical and biophysical research communications (20.05.2005)
Published in Biochemical and biophysical research communications (20.05.2005)
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Journal Article
Semi-online scheduling problems on m parallel identical machines
Jinzhi Tan
Published in 2011 6th IEEE Joint International Information Technology and Artificial Intelligence Conference (01.08.2011)
Published in 2011 6th IEEE Joint International Information Technology and Artificial Intelligence Conference (01.08.2011)
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Conference Proceeding
Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase N Terminus Is Indispensable for Proteolytic Activity but Not for Enzyme Dimerization
Chen, Shuai, Chen, Lili, Tan, Jinzhi, Chen, Jing, Du, Li, Sun, Tao, Shen, Jianhua, Chen, Kaixian, Jiang, Hualiang, Shen, Xu
Published in The Journal of biological chemistry (07.01.2005)
Published in The Journal of biological chemistry (07.01.2005)
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Journal Article
An optimal semi-online algorithm on the generalized machine covering problem
Jinzhi Tan
Published in 2011 IEEE 3rd International Conference on Communication Software and Networks (01.05.2011)
Published in 2011 IEEE 3rd International Conference on Communication Software and Networks (01.05.2011)
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Conference Proceeding
Structural and Functional Study of d-Glucuronyl C5-epimerase
Qin, Yi, Ke, Jiyuan, Gu, Xin, Fang, Jianping, Wang, Wucheng, Cong, Qifei, Li, Jie, Tan, Jinzhi, Brunzelle, Joseph S., Zhang, Chenghai, Jiang, Yi, Melcher, Karsten, Li, Jin-ping, Xu, H.Eric, Ding, Kan
Published in The Journal of biological chemistry (20.02.2015)
Published in The Journal of biological chemistry (20.02.2015)
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Journal Article
Sensitized Detection of Inhibitory Fragments and Iterative Development of Non-Peptidic Protease Inhibitors by Dynamic Ligation Screening
Schmidt, Marco Florian, Isidro-Llobet, Albert, Lisurek, Michael, El-Dahshan, Adeeb, Tan, Jinzhi, Hilgenfeld, Rolf, Rademann, Jörg
Published in Angewandte Chemie (International ed.) (14.04.2008)
Published in Angewandte Chemie (International ed.) (14.04.2008)
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Journal Article
pH-dependent Conformational Flexibility of the SARS-CoV Main Proteinase (M pro) Dimer: Molecular Dynamics Simulations and Multiple X-ray Structure Analyses
Tan, Jinzhi, Verschueren, Koen H.G., Anand, Kanchan, Shen, Jianhua, Yang, Maojun, Xu, Yechun, Rao, Zihe, Bigalke, Janna, Heisen, Burkhard, Mesters, Jeroen R., Chen, Kaixian, Shen, Xu, Jiang, Hualiang, Hilgenfeld, Rolf
Published in Journal of molecular biology (18.11.2005)
Published in Journal of molecular biology (18.11.2005)
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Journal Article
The “SARS-unique domain” (SUD) of SARS coronavirus is an oligo(G)-binding protein
Tan, Jinzhi, Kusov, Yuri, Mutschall, Doris, Tech, Stefanie, Nagarajan, Krishna, Hilgenfeld, Rolf, Schmidt, Christian L.
Published in Biochemical and biophysical research communications (28.12.2007)
Published in Biochemical and biophysical research communications (28.12.2007)
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Journal Article
Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations
Chen, Shuai, Chen, Lili, Tan, Jinzhi, Chen, Jing, Du, Li, Sun, Tao, Shen, Jianhua, Chen, Kaixian, Jiang, Hualiang, Shen, Xu
Published in The Journal of biological chemistry (07.01.2005)
Published in The Journal of biological chemistry (07.01.2005)
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Journal Article
Viral enzymes
Mesters, Jeroen R, Tan, Jinzhi, Hilgenfeld, Rolf
Published in Current opinion in structural biology (01.12.2006)
Published in Current opinion in structural biology (01.12.2006)
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Journal Article
The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes: e1000428
Tan, Jinzhi, Vonrhein, Clemens, Smart, Oliver S, Bricogne, Gerard, Bollati, Michela, Kusov, Yuri, Hansen, Guido, Mesters, Jeroen R, Schmidt, Christian L, Hilgenfeld, Rolf
Published in PLoS pathogens (01.05.2009)
Published in PLoS pathogens (01.05.2009)
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Journal Article