The P2X7 receptor contributes to seizures and inflammation‐driven long‐lasting brain hyperexcitability following hypoxia in neonatal mice
Smith, Jonathon, Menéndez Méndez, Aida, Alves, Mariana, Parras, Alberto, Conte, Giorgia, Bhattacharya, Anindya, Ceusters, Marc, Nicke, Annette, Henshall, David C., Jimenez‐Mateos, Eva M., Engel, Tobias
Published in British journal of pharmacology (01.07.2023)
Published in British journal of pharmacology (01.07.2023)
Get full text
Journal Article
MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset
Gross, Christina, Yao, Xiaodi, Engel, Tobias, Tiwari, Durgesh, Xing, Lei, Rowley, Shane, Danielson, Scott W., Thomas, Kristen T., Jimenez-Mateos, Eva M., Schroeder, Lindsay M., Pun, Raymund Y.K., Danzer, Steve C., Henshall, David C., Bassell, Gary J.
Published in Cell reports (Cambridge) (27.09.2016)
Published in Cell reports (Cambridge) (27.09.2016)
Get full text
Journal Article
Differently expression of the metabotropic P2Y receptor family after hypoxia-induced seizures in neonates and seizure suppression via P2Y1 receptor agonism
Smith, Jonathon, Lopez-Avila, Beatriz Gil, Engel, Tobias, Mateos, Eva M. Jimenez, Alves, Mariana
Published in Purinergic signalling (01.04.2024)
Published in Purinergic signalling (01.04.2024)
Get full text
Journal Article
Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus
Raoof, Rana, Jimenez-Mateos, Eva M., Bauer, Sebastian, Tackenberg, Björn, Rosenow, Felix, Lang, Johannes, Onugoren, Müjgan Dogan, Hamer, Hajo, Huchtemann, Tessa, Körtvélyessy, Peter, Connolly, Niamh M. C., Pfeiffer, Shona, Prehn, Jochen H. M., Farrell, Michael A., O’Brien, Donncha F., Henshall, David C., Mooney, Catherine
Published in Scientific reports (12.06.2017)
Published in Scientific reports (12.06.2017)
Get full text
Journal Article
Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy
Brennan, Gary P., Bauer, Sebastian, Engel, Tobias, Jimenez-Mateos, Eva M., Del Gallo, Federico, Hill, Thomas D.M., Connolly, Niamh M.C., Costard, Lara S., Neubert, Valentin, Salvetti, Beatrice, Sanz-Rodriguez, Amaya, Heiland, Mona, Mamad, Omar, Brindley, Elizabeth, Norwood, Braxton, Batool, Aasia, Raoof, Rana, El-Naggar, Hany, Reschke, Cristina R., Delanty, Norman, Prehn, Jochen H.M., Fabene, Paolo, Mooney, Catherine, Rosenow, Felix, Henshall, David C.
Published in Neurobiology of disease (01.10.2020)
Published in Neurobiology of disease (01.10.2020)
Get full text
Journal Article
“TORNADO” – Theranostic One-Step RNA Detector; microfluidic disc for the direct detection of microRNA-134 in plasma and cerebrospinal fluid
McArdle, Hazel, Jimenez-Mateos, Eva M., Raoof, Rana, Carthy, Eadaoin, Boyle, David, ElNaggar, Hany, Delanty, Norman, Hamer, Hajo, Dogan, Muejgdan, Huchtemann, Tessa, Kӧrtvelyessy, Peter, Rosenow, Felix, Forster, Robert J., Henshall, David C., Spain, Elaine
Published in Scientific reports (11.05.2017)
Published in Scientific reports (11.05.2017)
Get full text
Journal Article
Effects of hypoxia-induced neonatal seizures on acute hippocampal injury and later-life seizure susceptibility and anxiety-related behavior in mice
Rodriguez-Alvarez, Natalia, Jimenez-Mateos, Eva M, Dunleavy, Mark, Waddington, John L, Boylan, Geraldine B, Henshall, David C
Published in Neurobiology of disease (01.11.2015)
Published in Neurobiology of disease (01.11.2015)
Get full text
Journal Article
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis
McKiernan, Ross C, Jimenez-Mateos, Eva M, Bray, Isabella, Engel, Tobias, Brennan, Gary P, Sano, Takanori, Michalak, Zuzanna, Moran, Catherine, Delanty, Norman, Farrell, Michael, O'Brien, Donncha, Meller, Robert, Simon, Roger P, Stallings, Raymond L, Henshall, David C
Published in PloS one (15.05.2012)
Published in PloS one (15.05.2012)
Get full text
Journal Article
High Throughput qPCR Expression Profiling of Circulating MicroRNAs Reveals Minimal Sex- and Sample Timing-Related Variation in Plasma of Healthy Volunteers
Mooney, Catherine, Raoof, Rana, El-Naggar, Hany, Sanz-Rodriguez, Amaya, Jimenez-Mateos, Eva M, Henshall, David C
Published in PloS one (23.12.2015)
Published in PloS one (23.12.2015)
Get full text
Journal Article
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo
Brennan, Gary P, Jimenez-Mateos, Eva M, McKiernan, Ross C, Engel, Tobias, Tzivion, Guri, Henshall, David C
Published in PloS one (24.01.2013)
Published in PloS one (24.01.2013)
Get full text
Journal Article
P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice
Conte, Giorgia, Nguyen, Ngoc T., Alves, Mariana, de Diego-Garcia, Laura, Kenny, Aidan, Nicke, Annette, Henshall, David C., Jimenez-Mateos, Eva M., Engel, Tobias
Published in Frontiers in molecular neuroscience (12.08.2020)
Published in Frontiers in molecular neuroscience (12.08.2020)
Get full text
Journal Article
The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia
Quinlan, Sean, Merino-Serrais, Paula, Di Grande, Alessandra, Dussmann, Heiko, Prehn, Jochen H M, Ní Chonghaile, Tríona, Henshall, David C, Jimenez-Mateos, Eva M
Published in Frontiers in immunology (2019)
Published in Frontiers in immunology (2019)
Get full text
Journal Article
RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis
Mooney, Claire M., Jimenez-Mateos, Eva M., Engel, Tobias, Mooney, Catherine, Diviney, Mairead, Venø, Morten T., Kjems, Jørgen, Farrell, Michael A., O’Brien, Donncha F., Delanty, Norman, Henshall, David C.
Published in Scientific reports (27.01.2017)
Published in Scientific reports (27.01.2017)
Get full text
Journal Article
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma
Engel, Tobias, Murphy, Brona M, Hatazaki, Seiji, Jimenez-Mateos, Eva M, Concannon, Caoimhin G, Woods, Ina, Prehn, Jochen H.M, Henshall, David C
Published in The FASEB journal (01.03.2010)
Published in The FASEB journal (01.03.2010)
Get more information
Journal Article
Novel Point-of-Care Diagnostic Method for Neonatal Encephalopathy Using Purine Nucleosides
Beamer, Edward, O'Dea, Mary Isabel, Garvey, Aisling A, Smith, Jonathon, Menéndez-Méndez, Aida, Kelly, Lynne, Pavel, Andreea, Quinlan, Sean, Alves, Mariana, Jimenez-Mateos, Eva M, Tian, Faming, Dempsey, Eugene, Dale, Nicholas, Murray, Deirdre M, Boylan, Geraldine B, Molloy, Eleanor J, Engel, Tobias
Published in Frontiers in molecular neuroscience (09.09.2021)
Published in Frontiers in molecular neuroscience (09.09.2021)
Get full text
Journal Article
MicroRNAs in Neurodegenerative Diseases
Quinlan, Sean, Kenny, Aidan, Medina, Miguel, Engel, Tobias, Jimenez-Mateos, Eva M
Published in International review of cell and molecular biology (01.01.2017)
Published in International review of cell and molecular biology (01.01.2017)
Get full text
Journal Article
MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus
Beamer, Edward H, Jurado-Arjona, Jeronimo, Jimenez-Mateos, Eva M, Morgan, James, Reschke, Cristina R, Kenny, Aidan, de Leo, Gioacchino, Olivos-Oré, Luis A, Arribas-Blázquez, Marina, Madden, Stephen F, Merchán-Rubira, Jesús, Delanty, Norman, Farrell, Michael A, O'Brien, Donncha F, Avila, Jesus, Diaz-Hernandez, Miguel, Miras-Portugal, M Teresa, Artalejo, Antonio R, Hernandez, Felix, Henshall, David C, Engel, Tobias
Published in Frontiers in molecular neuroscience (11.12.2018)
Published in Frontiers in molecular neuroscience (11.12.2018)
Get full text
Journal Article