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Ivanova, Teodora, Hardes, Kornelia, Kallis, Stephanie, Dahms, Sven O., Than, Manuel E., Künzel, Sebastian, Böttcher‐Friebertshäuser, Eva, Lindberg, Iris, Jiao, Guan‐Sheng, Bartenschlager, Ralf, Steinmetzer, Torsten
Published in ChemMedChem (07.12.2017)
Published in ChemMedChem (07.12.2017)
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Small-Molecule Inhibitors of Lethal Factor Protease Activity Protect against Anthrax Infection
MOAYERI, Mahtab, CROWN, Devorah, JIAO, Guan-Sheng, SEONGJIN KIM, JOHNSON, Alan, LEYSATH, Clinton, LEPPLA, Stephen H
Published in Antimicrobial Agents and Chemotherapy (01.09.2013)
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Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays
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Published in Biochemical pharmacology (15.07.2015)
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Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine
Jiao, Guan-Sheng, Cregar, Lynne, Wang, Jinzhi, Millis, Sherri Z, Tang, Cho, O'Malley, Sean, Johnson, Alan T, Sareth, Sina, Larson, Jason, Thomas, Gary
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2006)
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Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility
Thompson, Aaron A, Jiao, Guan-Sheng, Kim, Seongjin, Thai, April, Cregar-Hernandez, Lynne, Margosiak, Stephen A, Johnson, Alan T, Han, Gye Won, O’Malley, Sean, Stevens, Raymond C
Published in Biochemistry (Easton) (17.05.2011)
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Small molecule proprotein convertase inhibitors for inhibition of embryo implantation
Ho, Huiting, Singh, Harmeet, Heng, Sophea, Nero, Tracy L, Paule, Sarah, Parker, Michael W, Johnson, Alan T, Jiao, Guan-Sheng, Nie, Guiying
Published in PloS one (04.12.2013)
Published in PloS one (04.12.2013)
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Syntheses, Photophysical Properties, and Application of Through-Bond Energy-Transfer Cassettes for Biotechnology
Jiao, Guan-Sheng, Thoresen, Lars H., Kim, Taeg Gyum, Haaland, Wade C., Gao, Feng, Topp, Michael R., Hochstrasser, Robin M., Metzker, Michael L., Burgess, Kevin
Published in Chemistry : a European journal (16.10.2006)
Published in Chemistry : a European journal (16.10.2006)
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Rigid, Conjugated, Fluoresceinated Thymidine Triphosphates: Syntheses and Polymerase Mediated Incorporation into DNA Analogues
Thoresen, Lars H., Jiao, Guan-Sheng, Haaland, Wade C., Metzker, Michael L., Burgess, Kevin
Published in Chemistry : a European journal (06.10.2003)
Published in Chemistry : a European journal (06.10.2003)
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Syntheses of Regioisomerically Pure 5- or 6-Halogenated Fluoresceins
Jiao, Guan-Sheng, Han, Jin Wook, Burgess, Kevin
Published in Journal of organic chemistry (17.10.2003)
Published in Journal of organic chemistry (17.10.2003)
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Microwave-Assisted Syntheses of Regioisomerically Pure Bromorhodamine Derivatives
Jiao, Guan-Sheng, Castro, Juan C, Thoresen, Lars H, Burgess, Kevin
Published in Organic letters (02.10.2003)
Published in Organic letters (02.10.2003)
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Small molecule inhibitors of anthrax edema factor
Jiao, Guan-Sheng, Kim, Seongjin, Moayeri, Mahtab, Thai, April, Cregar-Hernandez, Lynne, McKasson, Linda, O'Malley, Sean, Leppla, Stephen H., Johnson, Alan T.
Published in Bioorganic & medicinal chemistry letters (15.01.2018)
Published in Bioorganic & medicinal chemistry letters (15.01.2018)
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Antidotes to anthrax lethal factor intoxication. Part 2: Structural modifications leading to improved in vivo efficacy
Kim, Seongjin, Jiao, Guan-Sheng, Moayeri, Mahtab, Crown, Devorah, Cregar-Hernandez, Lynne, McKasson, Linda, Margosiak, Stephen A., Leppla, Stephen H., Johnson, Alan T.
Published in Bioorganic & medicinal chemistry letters (01.04.2011)
Published in Bioorganic & medicinal chemistry letters (01.04.2011)
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Antidotes to anthrax lethal factor intoxication. Part 1: Discovery of potent lethal factor inhibitors with in vivo efficacy
Jiao, Guan-Sheng, Kim, Seongjin, Moayeri, Mahtab, Cregar-Hernandez, Lynne, McKasson, Linda, Margosiak, Stephen A., Leppla, Stephen H., Johnson, Alan T.
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain
Jiao, Guan-Sheng, Kim, Seongjin, Moayeri, Mahtab, Crown, Devorah, Thai, April, Cregar-Hernandez, Lynne, McKasson, Linda, Sankaran, Banumathi, Lehrer, Axel, Wong, Teri, Johns, Lisa, Margosiak, Stephen A., Leppla, Stephen H., Johnson, Alan T.
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
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Virtual medicinal chemistry: In silico pre-docking functional group transformation for discovery of novel inhibitors of botulinum toxin serotype A light chain
O’Malley, Sean, Sareth, Sina, Jiao, Guan-Sheng, Kim, Seongjin, Thai, April, Cregar-Hernandez, Lynne, McKasson, Linda, Margosiak, Stephen A., Johnson, Alan T.
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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