Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
Su, Haixia, Yao, Sheng, Zhao, Wenfeng, Zhang, Yumin, Liu, Jia, Shao, Qiang, Wang, Qingxing, Li, Minjun, Xie, Hang, Shang, Weijuan, Ke, Changqiang, Feng, Lu, Jiang, Xiangrui, Shen, Jingshan, Xiao, Gengfu, Jiang, Hualiang, Zhang, Leike, Ye, Yang, Xu, Yechun
Published in Nature communications (15.06.2021)
Published in Nature communications (15.06.2021)
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Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
Jiang, Xiangrui, Su, Haixia, Shang, Weijuan, Zhou, Feng, Zhang, Yan, Zhao, Wenfeng, Zhang, Qiumeng, Xie, Hang, Jiang, Lei, Nie, Tianqing, Yang, Feipu, Xiong, Muya, Huang, Xiaoxing, Li, Minjun, Chen, Ping, Peng, Shaoping, Xiao, Gengfu, Jiang, Hualiang, Tang, Renhong, Zhang, Leike, Shen, Jingshan, Xu, Yechun
Published in Nature communications (13.10.2023)
Published in Nature communications (13.10.2023)
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SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
Xia, Bingqing, Shen, Xurui, He, Yang, Pan, Xiaoyan, Liu, Feng-Liang, Wang, Yi, Yang, Feipu, Fang, Sui, Wu, Yan, Duan, Zilei, Zuo, Xiaoli, Xie, Zhuqing, Jiang, Xiangrui, Xu, Ling, Chi, Hao, Li, Shuangqu, Meng, Qian, Zhou, Hu, Zhou, Yubo, Cheng, Xi, Xin, Xiaoming, Jin, Lin, Zhang, Hai-Lin, Yu, Dan-Dan, Li, Ming-Hua, Feng, Xiao-Li, Chen, Jiekai, Jiang, Hualiang, Xiao, Gengfu, Zheng, Yong-Tang, Zhang, Lei-Ke, Shen, Jingshan, Li, Jia, Gao, Zhaobing
Published in Cell research (01.08.2021)
Published in Cell research (01.08.2021)
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Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2
Kong, Xiangqian, Chen, Limin, Jiao, Lianying, Jiang, Xiangrui, Lian, Fulin, Lu, Junyan, Zhu, Kongkai, Du, Daohai, Liu, Jingqiu, Ding, Hong, Zhang, Naixia, Shen, Jingshan, Zheng, Mingyue, Chen, Kaixian, Liu, Xin, Jiang, Hualiang, Luo, Cheng
Published in Journal of medicinal chemistry (26.11.2014)
Published in Journal of medicinal chemistry (26.11.2014)
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9,10-Anhydrodehydroartemisinin Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Th1 and Th17 Cell Differentiation
Lv, Jie, Zhuang, Wei, Zhang, Yan, Xie, Ling, Xiang, Zhenglong, Zhao, Qingjie, Jiang, Xiangrui, Shen, Jingshan, Du, Changsheng
Published in Inflammation (01.10.2021)
Published in Inflammation (01.10.2021)
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Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review
Xie, Yuanchao, Ogah, Comfort Alicha, Jiang, Xiangrui, Li, Jianfeng, Shen, Jingshan
Published in Current drug targets (01.01.2016)
Published in Current drug targets (01.01.2016)
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The novel small-molecule TPN10456 inhibits Th17 cell differentiation and protects against experimental autoimmune encephalomyelitis
Yang, Cuixia, Lv, Jie, Jiang, Xiangrui, Xiang, Zhenglong, Gong, Ran, Xing, Jiahua, Liu, Guangyu, Xie, Ling, Saimaier, Kandireya, Zhang, Yan, Wang, Junjian, Shen, Hu, Pan, Juping, Shen, Jingshan, Du, Changsheng
Published in Cellular & molecular immunology (01.12.2020)
Published in Cellular & molecular immunology (01.12.2020)
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Monocyte apoptotic bodies are vehicles for influenza A virus propagation
Atkin-Smith, Georgia K., Duan, Mubing, Zanker, Damien J., Loh, Liyen, Nguyen, Thi H. O., Koutsakos, Marios, Nguyen, Tien, Jiang, Xiangrui, Carrera, Julio, Phan, Thanh Kha, Liu, Chuanxin, Paone, Stephanie, Oveissi, Sara, Hodge, Amy L., Baxter, Amy A., Kedzierska, Katherine, Mackenzie, Jason M., Hulett, Mark D., Bilsel, Pamuk, Chen, Weisan, Poon, Ivan K. H.
Published in Communications biology (08.05.2020)
Published in Communications biology (08.05.2020)
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Highly Efficient Heavy Ion Acceleration from Laser Interaction with Dusty Plasma
Zou, Debin, Yu, Mingyang, Jiang, Xiangrui, Zhao, Na, Yu, Tongpu, Zhuo, Hongbin, Pukhov, Alexander, Ma, Yanyun, Shao, Fuqiu, Zhou, Cangtao, Ruan, Shuangchen
Published in Advanced photonics research (01.07.2021)
Published in Advanced photonics research (01.07.2021)
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Repurposing of Rutan showed effective treatment for COVID-19 disease
Salikhov, Shavkat I, Abdurakhmonov, Ibrokhim Y, Oshchepkova, Yuliya I, Ziyavitdinov, Jamolitdin F, Berdiev, Nodir Sh, Aisa, Haji Akber, Shen, Jingshan, Xu, Yechun, Xu, H Eric, Jiang, Xiangrui, Zhang, Leike, Vypova, Natalia L, Allaberganov, Dilshod Sh, Tagayalieva, Nigora A, Musabaev, Erkin I, Ibadova, Gulnara A, Rajabov, Ilxom B, Lokteva, Lyubov M
Published in Frontiers in medicine (29.11.2023)
Published in Frontiers in medicine (29.11.2023)
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Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
Xu, Zhijian, Shi, Danrong, Han, Jian-Bao, Ling, Yun, Jiang, Xiangrui, Lu, Xiangyun, Li, Chuan, Gong, Likun, Ge, Guangbo, Zhang, Yani, Zang, Yi, Song, Tian-Zhang, Feng, Xiao-Li, Tian, Ren-Rong, Ji, Jia, Zhu, Miaojin, Wu, Nanping, Wu, Chunhui, Wang, Zhen, Xu, Yechun, Peng, Cheng, Zheng, Min, Yang, Junling, Du, Feifei, Wu, Junliang, Wang, Peipei, Shen, Jingshan, Zhang, Jianliang, Zheng, Yong-Tang, Yao, Hangping, Zhu, Weiliang
Published in Signal transduction and targeted therapy (24.04.2023)
Published in Signal transduction and targeted therapy (24.04.2023)
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Identification and characterization of novel amphioxus microRNAs by Solexa sequencing
Chen, Xi, Li, Qibin, Wang, Jin, Guo, Xing, Jiang, Xiangrui, Ren, Zhiji, Weng, Chunyue, Sun, Guoxun, Wang, Xiuqiang, Liu, Yaping, Ma, Lijia, Chen, Jun-Yuan, Wang, Jun, Zen, Ke, Zhang, Junfeng, Zhang, Chen-Yu
Published in Genome biology (01.01.2009)
Published in Genome biology (01.01.2009)
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Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives
Zheng, Wei, Wang, Zhen, Jiang, Xiangrui, Zhao, Qingjie, Shen, Jingshan
Published in Journal of medicinal chemistry (24.12.2020)
Published in Journal of medicinal chemistry (24.12.2020)
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Synthesis of telmisartan via oxidative cyclization
Li, Rui, Khakimov, Makhmudjon, Zhu, Fuqiang, Jiang, Xiangrui, Shen, Jingshan
Published in Tetrahedron (09.01.2023)
Published in Tetrahedron (09.01.2023)
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Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease
Shen, Wen, Chen, Xinyao, Zhou, Liping, Cheng, Yan, Zhang, Yan, Jiang, Xiangrui, Sun, Haiguo, Shen, Jingshan
Published in Bioorganic & medicinal chemistry letters (01.11.2024)
Published in Bioorganic & medicinal chemistry letters (01.11.2024)
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Molecular recognition of morphine and fentanyl by the human μ-opioid receptor
Zhuang, Youwen, Wang, Yue, He, Bingqing, He, Xinheng, Zhou, X. Edward, Guo, Shimeng, Rao, Qidi, Yang, Jiaqi, Liu, Jinyu, Zhou, Qingtong, Wang, Xiaoxi, Liu, Mingliang, Liu, Weiyi, Jiang, Xiangrui, Yang, Dehua, Jiang, Hualiang, Shen, Jingshan, Melcher, Karsten, Chen, Hong, Jiang, Yi, Cheng, Xi, Wang, Ming-Wei, Xie, Xin, Xu, H. Eric
Published in Cell (10.11.2022)
Published in Cell (10.11.2022)
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Dual-channel hypergraph convolutional network for predicting herb–disease associations
Hu, Lun, Zhang, Menglong, Hu, Pengwei, Zhang, Jun, Niu, Chao, Lu, Xueying, Jiang, Xiangrui, Ma, Yupeng
Published in Briefings in bioinformatics (22.01.2024)
Published in Briefings in bioinformatics (22.01.2024)
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Synthesis, cytotoxicity, and pharmacokinetic evaluations of niclosamide analogs for anti-SARS-CoV-2
Li, Rui, Zhang, Zherui, Huang, Shuhong, Peng, Ke, Jiang, Hualiang, Shen, Jingshan, Zhang, Bo, Jiang, Xiangrui
Published in European journal of medicinal chemistry (05.05.2023)
Published in European journal of medicinal chemistry (05.05.2023)
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Ultra-intense laser field amplification from a petawatt-class laser focusing in moderate density plasma
Li, Niehong, Zou, Debin, Zhao, Na, Jiang, Xiangrui, Shao, Fuqiu, Yu, Tongpu
Published in Optics express (24.10.2022)
Published in Optics express (24.10.2022)
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