I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles
Anilkumar, Gopinadhan N., Lesburg, Charles A., Selyutin, Oleg, Rosenblum, Stuart B., Zeng, Qingbei, Jiang, Yueheng, Chan, Tin-Yau, Pu, Haiyan, Vaccaro, Henry, Wang, Li, Bennett, Frank, Chen, Kevin X., Duca, Jose, Gavalas, Stephen, Huang, Yuhua, Pinto, Patrick, Sannigrahi, Mousumi, Velazquez, Francisco, Venkatraman, Srikanth, Vibulbhan, Bancha, Agrawal, Sony, Butkiewicz, Nancy, Feld, Boris, Ferrari, Eric, He, Zhiqing, Jiang, Chuan-kui, Palermo, Robert E., Mcmonagle, Patricia, Huang, H.-C., Shih, Neng-Yang, Njoroge, George, Kozlowski, Joseph A.
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokinetics
Venkatraman, Srikanth, Velazquez, Francisco, Gavalas, Stephen, Wu, Wanli, Chen, Kevin X., Nair, Anilkumar G., Bennett, Frank, Huang, Yuhua, Pinto, Patrick, Jiang, Yueheng, Selyutin, Oleg, Vibulbhan, Bancha, Zeng, Qingbei, Lesburg, Charles, Duca, Jose, Heimark, Larry, Huang, Hsueh-Cheng, Agrawal, Sony, Jiang, Chuan-kui, Ferrari, Eric, Li, Cheng, Kozlowski, Joseph, Rosenblum, Stuart, Shih, Neng-Yang, Njoroge, F. George
Published in Bioorganic & medicinal chemistry (01.01.2014)
Published in Bioorganic & medicinal chemistry (01.01.2014)
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Journal Article
Comparison of Methods for Transfection of Human Epidermal Keratinocytes
Jiang, Chuan-Kui, Connolly, Deirdre, Blumenberg, Miroslav
Published in Journal of investigative dermatology (01.12.1991)
Published in Journal of investigative dermatology (01.12.1991)
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Journal Article
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase
Venkatraman, Srikanth, Velazquez, Francisco, Gavalas, Stephen, Wu, Wanli, Chen, Kevin X., Nair, Anilkumar G., Bennett, Frank, Huang, Yuhua, Pinto, Patrick, Jiang, Yueheng, Selyutin, Oleg, Vibulbhan, Bancha, Zeng, Qingbei, Lesburg, Charles, Duca, Jose, Huang, Hsueh-Cheng, Agrawal, Sony, Jiang, Chuan-kui, Ferrari, Eric, Li, Cheng, Kozlowski, Joseph, Rosenblum, Stuart, Shih, Neng-Yang, Njoroge, F. George
Published in Bioorganic & medicinal chemistry (01.04.2013)
Published in Bioorganic & medicinal chemistry (01.04.2013)
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Journal Article
Discovery of an irreversible HCV NS5B polymerase inhibitor
Zeng, Qingbei, Nair, Anilkumar G., Rosenblum, Stuart B., Huang, Hsueh-Cheng, Lesburg, Charles A., Jiang, Yueheng, Selyutin, Oleg, Chan, Tin-Yau, Bennett, Frank, Chen, Kevin X., Venkatraman, Srikanth, Sannigrahi, Mousumi, Velazquez, Francisco, Duca, Jose S., Gavalas, Stephen, Huang, Yuhua, Pu, Haiyan, Wang, Li, Pinto, Patrick, Vibulbhan, Bancha, Agrawal, Sony, Ferrari, Eric, Jiang, Chuan-kui, Li, Cheng, Hesk, David, Gesell, Jennifer, Sorota, Steve, Shih, Neng-Yang, Njoroge, F. George, Kozlowski, Joseph A.
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides
Anilkumar, Gopinadhan N., Selyutin, Oleg, Rosenblum, Stuart B., Zeng, Qingbei, Jiang, Yueheng, Chan, Tin-Yau, Pu, Haiyan, Wang, Li, Bennett, Frank, Chen, Kevin X., Lesburg, Charles A., Duca, Jose, Gavalas, Stephen, Huang, Yuhua, Pinto, Patrick, Sannigrahi, Mousumi, Velazquez, Francisco, Venkatraman, Srikanth, Vibulbhan, Bancha, Agrawal, Sony, Ferrari, Eric, Jiang, Chuan-kui, Huang, H.-C., Shih, Neng-Yang, George Njoroge, F., Kozlowski, Joseph A.
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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Inhibitors of hepatitis C virus polymerase: Synthesis and characterization of novel 2-oxy-6-fluoro- N-(( S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides
Cheng, Cliff C., Shipps, Gerald W., Yang, Zhiwei, Kawahata, Noriyuki, Lesburg, Charles A., Duca, José S., Bandouveres, Jamie, Bracken, Jack D., Jiang, Chuan-kui, Agrawal, Sony, Ferrari, Eric, Huang, H.-C.
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
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Pyridine Carboxamides: Potent Palm Site Inhibitors of HCV NS5B Polymerase
Cheng, Cliff C, Huang, Xiaohua, Shipps, Gerald W, Wang, Yu-Sen, Wyss, Daniel F, Soucy, Kyle A, Jiang, Chuan-kui, Agrawal, Sony, Ferrari, Eric, He, Zhiqing, Huang, H.-C
Published in ACS medicinal chemistry letters (09.12.2010)
Published in ACS medicinal chemistry letters (09.12.2010)
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Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency
Hirschhorn, Rochelle, Yang, Diana Ruixi, Puck, Jennifer M, Huie, Maryann L, Jiang, Chuan-Kui, Kurlandsky, Lawrence E
Published in Nature genetics (01.07.1996)
Published in Nature genetics (01.07.1996)
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Journal Article
Inhibitors of hepatitis C virus polymerase: Synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzam ides
Cheng, Cliff C, Shipps, Gerald W, Yang, Zhiwei, Kawahata, Noriyuki, Lesburg, Charles A, Duca, Jose S, Bandouveres, Jamie, Bracken, Jack D, Jiang, Chuan-Kui, Agrawal, Sony, Ferrari, Eric, Huang, H-C
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
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Journal Article
Wound healing is accelerated by agonists of adenosine A sub(2) (G sub( alpha s)-linked) receptors
Montesinos, M C, Gadangi, P, Longaker, M, Sung, J, Levine, J, Nilsen, D, Reibman, J, Li, Min, Jiang, Chuan-Kui, Hirschhorn, R, Recht, P A, Ostad, E, Levin, R I, Cronstein, B N
Published in The Journal of experimental medicine (01.11.1997)
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Published in The Journal of experimental medicine (01.11.1997)
Journal Article
Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors
Montesinos, M C, Gadangi, P, Longaker, M, Sung, J, Levine, J, Nilsen, D, Reibman, J, Li, M, Jiang, C K, Hirschhorn, R, Recht, P A, Ostad, E, Levin, R I, Cronstein, B N
Published in The Journal of experimental medicine (03.11.1997)
Published in The Journal of experimental medicine (03.11.1997)
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