A Novel Dengue Virus Inhibitor, BP13944, Discovered by High-Throughput Screening with Dengue Virus Replicon Cells Selects for Resistance in the Viral NS2B/NS3 Protease
YANG, Chi-Chen, HU, Han-Shu, YUEH, Andrew, WU, Ren-Huang, WU, Szu-Huei, LEE, Shiow-Ju, JIAANG, Weir-Torn, CHERN, Jyh-Haur, HUANG, Zhi-Shun, WU, Huey-Nan, CHANG, Chung-Ming
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
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Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index than Sorafenib via Zebrafish Drug Screening Platform
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Published in Cancers (28.05.2019)
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Discovery of Conformational Control Inhibitors Switching off the Activated c‑KIT and Targeting a Broad Range of Clinically Relevant c‑KIT Mutants
Wu, Tsung-Sheng, Lin, Wen-Hsing, Tsai, Hui-Jen, Hsueh, Ching-Cheng, Hsu, Tsu, Wang, Pei-Chen, Lin, Hui-You, Peng, Yi-Hui, Lu, Cheng-Tai, Lee, Lung-Chun, Tu, Chih-Hsiang, Kung, Fang-Chun, Shiao, Hui-Yi, Yeh, Teng-Kuang, Song, Jen-Shin, Chang, Jia-Yu, Su, Yu-Chieh, Chen, Li-Tzong, Chen, Chiung-Tong, Jiaang, Weir-Torn, Wu, Su-Ying
Published in Journal of medicinal chemistry (25.04.2019)
Published in Journal of medicinal chemistry (25.04.2019)
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BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor
Tsai, Hui‐Jen, Jiaang, Weir‐Torn, Shih, Neng‐Yao, Fletcher, Jonathan A., Lin, Ming‐Jon, Yang, Ming‐Yu, Chen, Chiung‐Tong, Hsu, Tsu‐An John, Wu, Chun‐Chieh, Lin, Hui‐You, Chen, Li‐Tzong
Published in Cancer science (01.11.2018)
Published in Cancer science (01.11.2018)
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BPR1J373, an Oral Multiple Tyrosine Kinase Inhibitor, Targets c-KIT for the Treatment of c-KIT-Driven Myeloid Leukemia
Chen, Li-Tzong, Chen, Chiung-Tong, Jiaang, Weir-Torn, Chen, Tsai-Yun, Butterfield, Joseph H, Shih, Neng-Yao, Hsu, John Tsu-An, Lin, Hui-You, Lin, Sheng-Fung, Tsai, Hui-Jen
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Published in Molecular cancer therapeutics (01.10.2016)
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Optimization of Ligand and Lipophilic Efficiency To Identify an in Vivo Active Furano-Pyrimidine Aurora Kinase Inhibitor
Shiao, Hui-Yi, Coumar, Mohane Selvaraj, Chang, Chun-Wei, Ke, Yi-Yu, Chi, Ya-Hui, Chu, Chang-Ying, Sun, Hsu-Yi, Chen, Chun-Hwa, Lin, Wen-Hsing, Fung, Ka-Shu, Kuo, Po-Chu, Huang, Chin-Ting, Chang, Kai-Yen, Lu, Cheng-Tai, Hsu, John T. A, Chen, Chiung-Tong, Jiaang, Weir-Torn, Chao, Yu-Sheng, Hsieh, Hsing-Pang
Published in Journal of medicinal chemistry (11.07.2013)
Published in Journal of medicinal chemistry (11.07.2013)
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Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor
Wu, Jia-Jing, Tang, Hung-Kuan, Yeh, Teng-Kuang, Chen, Chi-Min, Shy, Hrong-Shing, Chu, Yue-Ru, Chien, Chia-Hui, Tsai, Ting-Yueh, Huang, Yu-Chen, Huang, Yu-Lin, Huang, Chih-Hsiang, Tseng, Huan-Yi, Jiaang, Weir-Torn, Chao, Yu-Sheng, Chen, Xin
Published in Biochemical pharmacology (15.07.2009)
Published in Biochemical pharmacology (15.07.2009)
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The dimeric transmembrane domain of prolyl dipeptidase DPP‐IV contributes to its quaternary structure and enzymatic activities
Chung, Kuei‐Min, Cheng, Jai‐Hong, Suen, Ching‐Shu, Huang, Chih‐Hsiang, Tsai, Cheng‐Han, Huang, Li‐Hao, Chen, Yi‐Rong, Wang, Andrew H.‐J., Jiaang, Weir‐Torn, Hwang, Ming‐Jing, Chen, Xin
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Published in Protein science (01.09.2010)
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Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer
Lin, Wen-Hsing, Yeh, Teng-Kuang, Jiaang, Weir-Torn, Yen, Kuei-Jung, Chen, Chun-Hwa, Huang, Chin-Ting, Yen, Shih-Chieh, Hsieh, Shu-Yi, Chou, Ling-Hui, Chen, Ching-Ping, Chiu, Chun-Hsien, Kao, Li-Chun, Chao, Yu-Sheng, Chen, Chiung-Tong, Hsu, John T-A
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Published in PloS one (08.01.2014)
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Resistance Studies of a Dithiazol Analogue, DBPR110, as a Potential Hepatitis C Virus NS5A Inhibitor in Replicon Systems
LIN, Hui-Mei, WANG, Jing-Chyi, CHAO, Yu-Sheng, CHERN, Jyh-Haur, YUEH, Andrew, HU, Han-Shu, WU, Pei-Shan, WANG, Wen-Hung, WU, Su-Ying, YANG, Chi-Chen, YEH, Teng-Kuang, HSU, Tsu-An, JIAANG, Weir-Torn
Published in Antimicrobial Agents and Chemotherapy (01.02.2013)
Published in Antimicrobial Agents and Chemotherapy (01.02.2013)
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Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8
Jiaang, Weir-Torn, Chen, Yuan-Shou, Hsu, Tsu, Wu, Ssu-Hui, Chien, Chia-Hui, Chang, Chung-Nien, Chang, Sheng-Ping, Lee, Shiow-Ju, Chen, Xin
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Resistance Analysis and Characterization of a Thiazole Analogue, BP008, as a Potent Hepatitis C Virus NS5A Inhibitor
LIN, Hui-Mei, WANG, Jing-Chyi, CHERN, Jyh-Haur, YEH, Teng-Kuang, YUEH, Andrew, HU, Han-Shu, WU, Pei-Shan, YANG, Chi-Chen, WU, Chung-Pu, PU, Szu-Yuan, HSU, Tsu-An, JIAANG, Weir-Torn, CHAO, Yu-Sheng
Published in Antimicrobial Agents and Chemotherapy (01.01.2012)
Published in Antimicrobial Agents and Chemotherapy (01.01.2012)
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Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2)
Lee, Lung-Chun, Peng, Yi-Hui, Chang, Hsin-Huei, Hsu, Tsu, Lu, Cheng-Tai, Huang, Chih-Hsiang, Hsueh, Ching-Cheng, Kung, Fang-Chun, Kuo, Ching-Chuan, Jiaang, Weir-Torn, Wu, Su-Ying
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity
Yeh, Kai-Chia, Yeh, Teng-Kuang, Huang, Chung-Yu, Hu, Chih-Bo, Wang, Min-Hsien, Huang, Yu-Wen, Chou, Ling-Hui, Ho, Hsuan-Hui, Song, Jen-Shin, Hsu, Tsu, Jiaang, Weir-Torn, Chao, Yu-Sheng, Chen, Chiung-Tong
Published in Life sciences (1973) (01.08.2021)
Published in Life sciences (1973) (01.08.2021)
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Pyrazolylamine Derivatives Reveal the Conformational Switching between Type I and Type II Binding Modes of Anaplastic Lymphoma Kinase (ALK)
Tu, Chih-Hsiang, Lin, Wen-Hsing, Peng, Yi-Hui, Hsu, Tsu, Wu, Jian-Sung, Chang, Chun-Yu, Lu, Cheng-Tai, Lyu, Ping-Chiang, Shih, Chuan, Jiaang, Weir-Torn, Wu, Su-Ying
Published in Journal of medicinal chemistry (28.04.2016)
Published in Journal of medicinal chemistry (28.04.2016)
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Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease
Lai, Zheng-Sheng, Yeh, Teng-Kuang, Chou, Yu-Chi, Hsu, Tsu, Lu, Cheng-Tai, Kung, Fang-Chun, Hsieh, Ming-Yen, Lin, Chun-Hung, Chen, Chiung-Tong, James Shen, Che-Kun, Jiaang, Weir-Torn
Published in European journal of medicinal chemistry (01.01.2021)
Published in European journal of medicinal chemistry (01.01.2021)
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Synthesis of 3,3-Dimethylglutamic Acid Derivatives as DPP-IV Inhibitors and Evaluation of Their Chemical Stability
Hsu, Tsu, Tsai, Ting-Yueh, Tseng, Ya-Ju, Chiou, Mei-Chun, Lu, Cheng-Tai, Chao, Yu-Sheng, Jiaang, Weir-Torn
Published in Journal of the Chinese Chemical Society (Taipei) (01.02.2011)
Published in Journal of the Chinese Chemical Society (Taipei) (01.02.2011)
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Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia
Lin, Wen-Hsing, Wu, Su-Ying, Yeh, Teng-Kuang, Chen, Chiung-Tong, Song, Jen-Shin, Shiao, Hui-Yi, Kuo, Ching-Chuan, Hsu, Tsu, Lu, Cheng-Tai, Wang, Pei-Chen, Wu, Tsung-Sheng, Peng, Yi-Hui, Lin, Hui-You, Chen, Ching-Ping, Weng, Ya-Ling, Kung, Fang-Chun, Wu, Mine-Hsine, Su, Yu-Chieh, Huang, Kuo-Wei, Chou, Ling-Hui, Hsueh, Ching-Cheng, Yen, Kuei-Jung, Kuo, Po-Chu, Huang, Chen-Lung, Chen, Li-Tzong, Shih, Chuan, Tsai, Hui-Jen, Jiaang, Weir-Torn
Published in Journal of medicinal chemistry (26.12.2019)
Published in Journal of medicinal chemistry (26.12.2019)
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Facile Solid-Phase Synthesis of an Antifreeze Glycoprotein
Tseng, Ping-Hui, Jiaang, Weir-Torn, Chang, Meng-Yang, Chen, Shui-Tein
Published in Chemistry : a European journal (02.02.2001)
Published in Chemistry : a European journal (02.02.2001)
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