Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation
Dey, Asim B., Khedr, Sherif, Bean, James, Porras, Leah L., Meredith, Tamika D., Willard, Francis S., Hass, Joseph V., Zhou, Xin, Terashvili, Maia, Jesudason, Cynthia D., Ruley, Kevin M., Wiley, Michael R., Kowala, Mark, Atkinson, Simon J., Staruschenko, Alexander, Rekhter, Mark D.
Published in Frontiers in physiology (08.09.2020)
Published in Frontiers in physiology (08.09.2020)
Get full text
Journal Article
SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease
Jesudason, Cynthia D., Mason, Emily R., Chu, Shaoyou, Oblak, Adrian L., Javens‐Wolfe, June, Moussaif, Mustapha, Durst, Greg, Hipskind, Philip, Beck, Daniel E., Dong, Jiajun, Amarasinghe, Ovini, Zhang, Zhong‐Yin, Hamdani, Adam K., Singhal, Kratika, Mesecar, Andrew D., Souza, Sarah, Jacobson, Marlene, Salvo, Jerry Di, Soni, Disha M., Kandasamy, Murugesh, Masters, Andrea R., Quinney, Sara K, Doolen, Suzanne, Huhe, Hasi, Rizzo, Stacey J. Sukoff, Lamb, Bruce T., Palkowitz, Alan D., Richardson, Timothy I.
Published in Alzheimer's & dementia : translational research & clinical interventions (01.10.2023)
Published in Alzheimer's & dementia : translational research & clinical interventions (01.10.2023)
Get full text
Journal Article
LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy
Fitch, Thomas E, Benvenga, Mark J, Jesudason, Cynthia D, Zink, Charity, Vandergriff, Amy B, Menezes, Michelle M, Schober, Douglas A, Rorick-Kehn, Linda M
Published in Frontiers in neuroscience (2014)
Published in Frontiers in neuroscience (2014)
Get full text
Journal Article
The First Synthesis of a Daphnane Diterpene: The Enantiocontrolled Total Synthesis of (+)-Resiniferatoxin
Wender, Paul A, Jesudason, Cynthia D, Nakahira, Hiroyuki, Tamura, Norikazu, Tebbe, Anne Louise, Ueno, Yoshihide
Published in Journal of the American Chemical Society (31.12.1997)
Published in Journal of the American Chemical Society (31.12.1997)
Get full text
Journal Article
Synthesis and SAR of novel histamine H3 receptor antagonists
Jesudason, Cynthia D., Beavers, Lisa S., Cramer, Jeffrey W., Dill, Joelle, Finley, Don R., Lindsley, Craig W., Stevens, F. Craig, Gadski, Robert A., Oldham, Samuel W., Pickard, R. Todd, Siedem, Christopher S., Sindelar, Dana K., Singh, Ajay, Watson, Brian M., Hipskind, Philip A.
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Get full text
Journal Article
PET ligands [ 18 F]LSN3316612 and [ 11 C]LSN3316612 quantify O -linked-β- N -acetyl-glucosamine hydrolase in the brain
Lu, Shuiyu, Haskali, Mohammad B, Ruley, Kevin M, Dreyfus, Nicolas J-F, DuBois, Susan L, Paul, Soumen, Liow, Jeih-San, Morse, Cheryl L, Kowalski, Aneta, Gladding, Robert L, Gilmore, Jeremy, Mogg, Adrian J, Morin, S Michelle, Lindsay-Scott, Peter J, Ruble, J Craig, Kant, Nancy A, Shcherbinin, Sergey, Barth, Vanessa N, Johnson, Michael P, Cuadrado, Maria, Jambrina, Enrique, Mannes, Andrew J, Nuthall, Hugh N, Zoghbi, Sami S, Jesudason, Cynthia D, Innis, Robert B, Pike, Victor W
Published in Science translational medicine (13.05.2020)
Published in Science translational medicine (13.05.2020)
Get more information
Journal Article
Combination of a Beta Adrenoceptor Modulator and a Norepinephrine-Serotonin Uptake Inhibitor for the Treatment of Obesity
Jesudason, Cynthia D., Baker, James E., Bryant, Robert D., Fisher, Jack W., O’Farrell, Libbey S., Gaich, Gregory A., He, Minxia M., Kahl, Steven D., Kriauciunas, Aidas V., Heiman, Mark L., Peters, Mary A., Rito, Christopher J., Satterwhite, Julie H., Tinsley, Frank C., Trankle, William G., Shuker, Anthony J.
Published in ACS medicinal chemistry letters (11.08.2011)
Published in ACS medicinal chemistry letters (11.08.2011)
Get full text
Journal Article
Potent oxindole based human β3 adrenergic receptor agonists
STEVENS, F. Craig, BLOOMQUIST, William E, BOREL, Anthony G, COHEN, Marlene L, DROSTE, Christine A, HEIMAN, Mark L, KRIAUCIUNAS, Aidas, SALL, Daniel J, TINSLEY, Frank C, JESUDASON, Cynthia D
Published in Bioorganic & medicinal chemistry letters (15.11.2007)
Published in Bioorganic & medicinal chemistry letters (15.11.2007)
Get full text
Journal Article
Potent benzimidazolone based human beta(3)-adrenergic receptor agonists
Finley, Don R, Bell, Michael G, Borel, Anthony G, Bloomquist, William E, Cohen, Marlene L, Heiman, Mark L, Kriauciunas, Aidas, Matthews, Donald P, Miles, Tania, Neel, David A, Rito, Christopher J, Sall, Daniel J, Shuker, Anthony J, Stephens, Thomas W, Tinsley, Frank C, Winter, Mark A, Jesudason, Cynthia D
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Get full text
Journal Article
Potent benzimidazolone based human β3-adrenergic receptor agonists
FINLEY, Don R, BELL, Michael G, RITO, Christopher J, SAIL, Daniel J, SHUKER, Anthony J, STEPHENS, Thomas W, TINSLEY, Frank C, WINTER, Mark A, JESUDASON, Cynthia D, BOREL, Anthony G, BLOOMQUIST, William E, COHEN, Marlene L, HEIMAN, Mark. L, KRIAUCIUNAS, Aidas, MATTHEWS, Donald P, MILES, Tania, NEEL, David A
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Get full text
Journal Article
A Target Enablement Package for the Inhibition of SHIP1 as a Therapeutic Strategy for the Treatment of Alzheimer’s Disease
Richardson, Timothy I, Jesudason, Cynthia D, Lobb, Karen L, Durst, Gregory L, Clayton, Brent, Massey, Steven M, Beck, Daniel E, Zhang, Zhong‐Yin, Dong, Jiajun, Lin, Jianping, Miao, Jinmin, Putt, Karson S, Mesecar, Andrew D, Hamdani, Adam K, Lendy, Emma K, Souza, Sarah, Jacobson, Marlene, Salvo, Jerry Di, Chu, Shaoyou, Mason, Emily R, Oblak, Adrian L, Soni, Disha, Quinney, Sara K, Silva, Larissa L, Kandasamy, Murugesh, Masters, Andrea R, Rizzo, Stacey J Sukoff, Doolen, Suzanne, Huang, Kun, Zhang, Jie, Lamb, Bruce T, Palkowitz, Alan D
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
Get full text
Journal Article
The use of high-throughput synthesis and purification in the preparation of a directed library of adrenergic agents
Siegel, M G, Shuker, A J, Droste, C A, Hahn, P J, Jesudason, C D, McDonald, 3rd, J H, Matthews, D P, Rito, C J, Thorpe, A J
Published in Molecular diversity (1997)
Published in Molecular diversity (1997)
Get full text
Journal Article
Potent oxindole based human beta sub(3) adrenergic receptor agonists
Stevens, FCraig, Bloomquist, William E, Borel, Anthony G, Cohen, Marlene L, Droste, Christine A, Heiman, Mark L, Kriauciunas, Aidas, Sall, Daniel J, Tinsley, Frank C, Jesudason, Cynthia D
Published in Bioorganic & medicinal chemistry (01.11.2007)
Published in Bioorganic & medicinal chemistry (01.11.2007)
Get full text
Journal Article
Potent oxindole based human beta3 adrenergic receptor agonists
Stevens, F Craig, Bloomquist, William E, Borel, Anthony G, Cohen, Marlene L, Droste, Christine A, Heiman, Mark L, Kriauciunas, Aidas, Sall, Daniel J, Tinsley, Frank C, Jesudason, Cynthia D
Published in Bioorganic & medicinal chemistry letters (15.11.2007)
Get full text
Published in Bioorganic & medicinal chemistry letters (15.11.2007)
Journal Article
Potent oxindole based human β 3 adrenergic receptor agonists
Stevens, F. Craig, Bloomquist, William E., Borel, Anthony G., Cohen, Marlene L., Droste, Christine A., Heiman, Mark L., Kriauciunas, Aidas, Sall, Daniel J., Tinsley, Frank C., Jesudason, Cynthia D.
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
Get full text
Journal Article
Synthesis and SAR of novel histamine H sub(3) receptor antagonists
Jesudason, Cynthia D, Beavers, Lisa S, Cramer, Jeffrey W, Dill, Joelle, Finley, Don R, Lindsley, Craig W, Stevens, FCraig, Gadski, Robert A, Oldham, Samuel W, Pickard, RTodd, Siedem, Christopher S, Sindelar, Dana K, Singh, Ajay, Watson, Brian M, Hipskind, Philip A
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Get full text
Journal Article
Potent benzimidazolone based human beta sub(3)-adrenergic receptor agonists
Finley, Don R, Bell, Michael G, Borel, Anthony G, Bloomquist, William E, Cohen, Marlene L, Heiman, MarkL, Kriauciunas, Aidas, Matthews, Donald P, Miles, Tania, Neel, David A, Rito, Christopher J, Sall, Daniel J, Shuker, Anthony J, Stephens, Thomas W, Tinsley, Frank C, Winter, Mark A, Jesudason, Cynthia D
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Get full text
Journal Article
Potent benzimidazolone based human β 3-adrenergic receptor agonists
Finley, Don R., Bell, Michael G., Borel, Anthony G., Bloomquist, William E., Cohen, Marlene L., Heiman, Mark. L., Kriauciunas, Aidas, Matthews, Donald P., Miles, Tania, Neel, David A., Rito, Christopher J., Sall, Daniel J., Shuker, Anthony J., Stephens, Thomas W., Tinsley, Frank C., Winter, Mark A., Jesudason, Cynthia D.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
Get full text
Journal Article