Identification and characterization of 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a novel dual tumor necrosis factor-alpha-converting enzyme/matrix metalloprotease inhibitor for the treatment of rheumatoid arthritis
Zhang, Yuhua, Xu, Jun, Levin, Jeremy, Hegen, Martin, Li, Guangde, Robertshaw, Heidi, Brennan, Fionula, Cummons, Terri, Clarke, Dave, Vansell, Nichole, Nickerson-Nutter, Cheryl, Barone, Dauphine, Mohler, Ken, Black, Roy, Skotnicki, Jerry, Gibbons, Jay, Feldmann, Marc, Frost, Philip, Larsen, Glenn, Lin, Lih-Ling
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
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Journal Article
Identification of potent and selective MMP-13 inhibitors
Wu, Junjun, Rush, Thomas S., Hotchandani, Rajeev, Du, Xuemei, Geck, Mary, Collins, Elisabeth, Xu, Zhang-Bao, Skotnicki, Jerry, Levin, Jeremy I., Lovering, Frank E.
Published in Bioorganic & medicinal chemistry letters (15.09.2005)
Published in Bioorganic & medicinal chemistry letters (15.09.2005)
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Journal Article
Characterization of (2 R, 3 S)-2-({[4-(2-butynyloxy)phenyl]sulfonyl}amino)- N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-α converting enzyme
Zhang, Yuhua, Hegen, Martin, Xu, Jun, Keith, James C., Jin, Guixian, Du, Xuemei, Cummons, Terri, Sheppard, Barbara J., Sun, LinHong, Zhu, Yi, Rao, Vikram R., Wang, Qin, Xu, Weixin, Cowling, Rebecca, Nickerson-Nutter, Cheryl L., Gibbons, Jay, Skotnicki, Jerry, Lin, Lih-Ling, Levin, Jeremy
Published in International immunopharmacology (20.12.2004)
Published in International immunopharmacology (20.12.2004)
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Journal Article
Identification and Characterization of 4-[[4-(2-Butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a Novel Dual Tumor Necrosis Factor-α-Converting Enzyme/Matrix Metalloprotease Inhibitor for the Treatment of Rheumatoid Arthritis
Yuhua Zhang, Jun Xu, Jeremy Levin, Martin Hegen, Guangde Li, Heidi Robertshaw, Fionula Brennan, Terri Cummons, Dave Clarke, Nichole Vansell, Cheryl Nickerson-Nutter, Dauphine Barone, Ken Mohler, Roy Black, Jerry Skotnicki, Jay Gibbons, Marc Feldmann, Philip Frost, Glenn Larsen, Lih-Ling Lin
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
Get full text
Journal Article
Identification of Potent and Selective MMP-13 Inhibitors
Wu, Junjun, Rush, Thomas S. III, Hotchandani, Rajeev, Du, Xuemei, Geck, Mary, Collins, Elisabeth, Xu, Zhang-Bao, Skotnicki, Jerry, Levin, Jeremy I., Lovering, Frank E.
Published in ChemInform (06.12.2005)
Published in ChemInform (06.12.2005)
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