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Ethanol exposure drives colon location specific cell composition changes in a normal colon crypt 3D organoid model
Devall, Matthew, Plummer, Sarah J., Bryant, Jennifer, Jennelle, Lucas T., Eaton, Stephen, Dampier, Christopher H., Huyghe, Jeroen R., Peters, Ulrike, Powell, Steven M., Casey, Graham
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Published in Scientific reports (11.01.2021)
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Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 Mutation
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Published in Diabetes (New York, N.Y.) (01.11.2013)
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A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study
Dong, Xinyuan, Su, Yu-Ru, Barfield, Richard, Bien, Stephanie A, He, Qianchuan, Harrison, Tabitha A, Huyghe, Jeroen R, Keku, Temitope O, Lindor, Noralane M, Schafmayer, Clemens, Chan, Andrew T, Gruber, Stephen B, Jenkins, Mark A, Kooperberg, Charles, Peters, Ulrike, Hsu, Li
Published in PLoS genetics (24.08.2020)
Published in PLoS genetics (24.08.2020)
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Identification of Novel Loci and New Risk Variant in Known Loci for Colorectal Cancer Risk in East Asians
Lu, Yingchang, Kweon, Sun-Seog, Cai, Qiuyin, Tanikawa, Chizu, Shu, Xiao-Ou, Jia, Wei-Hua, Xiang, Yong-Bing, Huyghe, Jeroen R, Harrison, Tabitha A, Kim, Jeongseon, Shin, Aesun, Kim, Dong-Hyun, Matsuo, Keitaro, Jee, Sun Ha, Guo, Xingyi, Wen, Wanqing, Shi, Jiajun, Li, Bingshan, Wang, Nan, Shin, Min-Ho, Li, Hong-Lan, Ren, Zefang, Oh, Jae Hwan, Oze, Isao, Ahn, Yoon-Ok, Jung, Keum Ji, Gao, Jing, Gao, Yu-Tang, Pan, Zhi-Zhong, Kamatani, Yoichiro, Chan, Andrew T, Gsur, Andrea, Hampe, Jochen, Le Marchand, Loic, Li, Li, Lindblom, Annika, Moreno, Victor, Newcomb, Polly A, Offit, Kenneth, Pharoah, Paul D P, van Duijnhoven, Franzel J B, Van Guelpen, Bethany, Vodicka, Pavel, Weinstein, Stephanie J, Wolk, Alicja, Wu, Anna H, Hsu, Li, Zeng, Yi-Xin, Long, Jirong, Peters, Ulrike, Matsuda, Koichi, Zheng, Wei
Published in Cancer epidemiology, biomarkers & prevention (01.02.2020)
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A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell
Kulzer, Jennifer R., Stitzel, Michael L., Morken, Mario A., Huyghe, Jeroen R., Fuchsberger, Christian, Kuusisto, Johanna, Laakso, Markku, Boehnke, Michael, Collins, Francis S., Mohlke, Karen L.
Published in American journal of human genetics (06.02.2014)
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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
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Published in PLoS genetics (30.10.2017)
Published in PLoS genetics (30.10.2017)
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Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol
Roman, Tamara S., Marvelle, Amanda F., Fogarty, Marie P., Vadlamudi, Swarooparani, Gonzalez, Arlene J., Buchkovich, Martin L., Huyghe, Jeroen R., Fuchsberger, Christian, Jackson, Anne U., Wu, Ying, Civelek, Mete, Lusis, Aldons J., Gaulton, Kyle J., Sethupathy, Praveen, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Boehnke, Michael, Mohlke, Karen L.
Published in American journal of human genetics (03.12.2015)
Published in American journal of human genetics (03.12.2015)
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Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk
Shu, Xiang, Chen, Zhishan, Long, Jirong, Guo, Xingyi, Yang, Yaohua, Qu, Conghui, Ahn, Yoon-Ok, Cai, Qiuyin, Casey, Graham, Gruber, Stephen B, Huyghe, Jeroen R, Jee, Sun Ha, Jenkins, Mark A, Jia, Wei-Hua, Jung, Keum Ji, Kamatani, Yoichiro, Kim, Dong-Hyun, Kim, Jeongseon, Kweon, Sun-Seog, Le Marchand, Loic, Matsuda, Koichi, Matsuo, Keitaro, Newcomb, Polly A, Oh, Jae Hwan, Ose, Jennifer, Oze, Isao, Pai, Rish K, Pan, Zhi-Zhong, Pharoah, Paul D P, Playdon, Mary C, Ren, Ze-Fang, Schoen, Robert E, Shin, Aesun, Shin, Min-Ho, Shu, Xiao-Ou, Sun, Xiaohui, Tangen, Catherine M, Tanikawa, Chizu, Ulrich, Cornelia M, van Duijnhoven, Franzel J B, Van Guelpen, Bethany, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Peters, Ulrike, Zheng, Wei
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Identifying metabolic features of colorectal cancer liability using Mendelian randomization
Bull, Caroline, Hazelwood, Emma, Bell, Joshua A, Tan, Vanessa, Constantinescu, Andrei-Emil, Borges, Carolina, Legge, Danny, Burrows, Kimberley, Huyghe, Jeroen R, Brenner, Hermann, Castellvi-Bel, Sergi, Chan, Andrew T, Kweon, Sun-Seog, Le Marchand, Loic, Li, Li, Cheng, Iona, Pai, Rish K, Figueiredo, Jane C, Murphy, Neil, Gunter, Marc J, Timpson, Nicholas J, Vincent, Emma E
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Published in eLife (21.12.2023)
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Association between germline variants and somatic mutations in colorectal cancer
Barfield, Richard, Qu, Conghui, Steinfelder, Robert S., Zeng, Chenjie, Harrison, Tabitha A., Brezina, Stefanie, Buchanan, Daniel D., Campbell, Peter T., Casey, Graham, Gallinger, Steven, Giannakis, Marios, Gruber, Stephen B., Gsur, Andrea, Hsu, Li, Huyghe, Jeroen R., Moreno, Victor, Newcomb, Polly A., Ogino, Shuji, Phipps, Amanda I., Slattery, Martha L., Thibodeau, Stephen N., Trinh, Quang M., Toland, Amanda E., Hudson, Thomas J., Sun, Wei, Zaidi, Syed H., Peters, Ulrike
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One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status
Myte, Robin, Gylling, Björn, Häggström, Jenny, Schneede, Jörn, Löfgren-Burström, Anna, Huyghe, Jeroen R, Hallmans, Göran, Meyer, Klaus, Johansson, Ingegerd, Ueland, Per Magne, Palmqvist, Richard, Van Guelpen, Bethany
Published in PloS one (25.04.2018)
Published in PloS one (25.04.2018)
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T cell‐inflamed gene expression profile is associated with favorable disease‐specific survival in non‐hypermutated microsatellite‐stable colorectal cancer patients
Yin, Hang, Harrison, Tabitha A., Thomas, Sushma S., Sather, Cassie L., Koehne, Amanda L., Malen, Rachel C., Reedy, Adriana M., Wurscher, Michelle A., Hsu, Li, Phipps, Amanda I., Zaidi, Syed H. E., Newcomb, Polly A., Peters, Ulrike, Huyghe, Jeroen R.
Published in Cancer medicine (Malden, MA) (01.03.2023)
Published in Cancer medicine (Malden, MA) (01.03.2023)
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A genome-wide association study for age-related hearing impairment in the Saami
VAN LAER, Lut, HUYGHE, Jeroen R, HUENTELMAN, Matthew J, VAN CAMP, Guy, HANNULA, Samuli, VAN EYKEN, Els, STEPHAN, Dietrich A, MÄKI-TORKKO, Elina, AIKIO, Pekka, FRANSEN, Erik, LYSHOLM-BERNACCHI, Alana, SORRI, Martti
Published in European journal of human genetics : EJHG (01.06.2010)
Published in European journal of human genetics : EJHG (01.06.2010)
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Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals
Chen, Hongjie, Majumdar, Arunabha, Wang, Lu, Kar, Siddhartha, Brown, Kevin M., Feng, Helian, Turman, Constance, Dennis, Joe, Easton, Douglas, Michailidou, Kyriaki, Simard, Jacques, Bishop, Timothy, Cheng, Iona C., Huyghe, Jeroen R., Schmit, Stephanie L., O’Mara, Tracy A., Spurdle, Amanda B., Gharahkhani, Puya, Schumacher, Johannes, Jankowski, Janusz, Gockel, Ines, Bondy, Melissa L., Houlston, Richard S., Jenkins, Robert B., Melin, Beatrice, Lesseur, Corina, Ness, Andy R., Diergaarde, Brenda, Olshan, Andrew F., Amos, Christopher I., Christiani, David C., Landi, Maria T., McKay, James D., Brossard, Myriam, Iles, Mark M., Law, Matthew H., MacGregor, Stuart, Beesley, Jonathan, Jones, Michelle R., Tyrer, Jonathan, Winham, Stacey J., Klein, Alison P., Petersen, Gloria, Li, Donghui, Wolpin, Brian M., Eeles, Rosalind A., Haiman, Christopher A., Kote-Jarai, Zsofia, Schumacher, Fredrick R., Brennan, Paul, Chanock, Stephen J., Gaborieau, Valerie, Purdue, Mark P., Pharoah, Paul, Hung, Rayjean J., Amundadottir, Laufey T., Kraft, Peter, Pasaniuc, Bogdan, Lindström, Sara
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Published in HGG advances (08.07.2021)
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Evaluation of host genetic and viral factors as surrogate markers for HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian HTLV-1-infected patients
Talledo, Michael, López, Giovanni, Huyghe, Jeroen R, Verdonck, Kristien, Adaui, Vanessa, González, Elsa, Best, Iván, Clark, Daniel, Vanham, Guido, Gotuzzo, Eduardo, Van Camp, Guy, Van Laer, Lut
Published in Journal of medical virology (01.03.2010)
Published in Journal of medical virology (01.03.2010)
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Genetic signature of population fragmentation varies with mobility in seven bird species of a fragmented Kenyan cloud forest
Callens, Tom, Galbusera, Peter, Matthysen, Erik, Durand, Eric Y, Githiru, Mwangi, Huyghe, Jeroen R, Lens, Luc
Published in Molecular ecology (01.05.2011)
Published in Molecular ecology (01.05.2011)
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Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study
Constantinescu, Andrei-Emil, Bull, Caroline J, Jones, Nicholas, Mitchell, Ruth, Burrows, Kimberley, Dimou, Niki, Bézieau, Stéphane, Brenner, Hermann, Buchanan, Daniel D, D'Amato, Mauro, Jenkins, Mark A, Moreno, Victor, Pai, Rish K, Um, Caroline Y, White, Emily, Murphy, Neil, Gunter, Marc, Timpson, Nicholas J, Huyghe, Jeroen R, Vincent, Emma E
Published in International journal of cancer (01.01.2024)
Published in International journal of cancer (01.01.2024)
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Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
Huyghe, Jeroen R, Jackson, Anne U, Fogarty, Marie P, Buchkovich, Martin L, Stančáková, Alena, Stringham, Heather M, Sim, Xueling, Yang, Lingyao, Fuchsberger, Christian, Cederberg, Henna, Chines, Peter S, Teslovich, Tanya M, Romm, Jane M, Ling, Hua, McMullen, Ivy, Ingersoll, Roxann, Pugh, Elizabeth W, Doheny, Kimberly F, Neale, Benjamin M, Daly, Mark J, Kuusisto, Johanna, Scott, Laura J, Kang, Hyun Min, Collins, Francis S, Abecasis, Gonçalo R, Watanabe, Richard M, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Published in Nature genetics (01.02.2013)
Published in Nature genetics (01.02.2013)
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