First‐in‐Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers
Fox, Jonathan C., Hellawell, Jennifer L., Rao, Satish, O'Reilly, Terry, Lumpkin, Rick, Jernelius, Jesper, Gretler, Daniel, Sinha, Uma
Published in Clinical pharmacology in drug development (01.01.2020)
Published in Clinical pharmacology in drug development (01.01.2020)
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Design of Annulated Pyrazoles as Inhibitors of HIV-1 Reverse Transcriptase
Sweeney, Zachary K, Harris, Seth F, Arora, Nidhi, Javanbakht, Hassan, Li, Yu, Fretland, Jennifer, Davidson, James P, Billedeau, J. Roland, Gleason, Shelley K, Hirschfeld, Donald, Kennedy-Smith, Joshua J, Mirzadegan, Taraneh, Roetz, Ralf, Smith, Mark, Sperry, Sarah, Suh, Judy M, Wu, Jeffrey, Tsing, Stan, Villaseñor, Armando G, Paul, Amber, Su, Guoping, Heilek, Gabrielle, Hang, Julie Q, Zhou, Amy S, Jernelius, Jesper A, Zhang, Fang-Jie, Klumpp, Klaus
Published in Journal of medicinal chemistry (11.12.2008)
Published in Journal of medicinal chemistry (11.12.2008)
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Journal Article
Enantioselective Synthesis of Medium-Ring Heterocycles, Tertiary Ethers, and Tertiary Alcohols by Mo−Catalyzed Ring-Closing Metathesis
Kiely, Andrew F, Jernelius, Jesper A, Schrock, Richard R, Hoveyda, Amir H
Published in Journal of the American Chemical Society (27.03.2002)
Published in Journal of the American Chemical Society (27.03.2002)
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Journal Article
An Enantiomerically Pure Adamantylimido Molybdenum Alkylidene Complex. An Effective New Catalyst for Enantioselective Olefin Metathesis
Tsang, W. C. Peter, Jernelius, Jesper A, Cortez, G. A, Weatherhead, Gabriel S, Schrock, Richard R, Hoveyda, Amir H
Published in Journal of the American Chemical Society (05.03.2003)
Published in Journal of the American Chemical Society (05.03.2003)
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Journal Article
Diphenyl Ether Non-Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties
Sweeney, Zachary K., Kennedy-Smith, Joshua J., Wu, Jeffrey, Arora, Nidhi, Billedeau, J. Roland, Davidson, James P., Fretland, Jennifer, Hang, Julie Q., Heilek, Gabrielle M., Harris, Seth F., Hirschfeld, Donald, Inbar, Petra, Javanbakht, Hassan, Jernelius, Jesper A., Jin, Qingwu, Li, Yu, Liang, Weiling, Roetz, Ralf, Sarma, Keshab, Smith, Mark, Stefanidis, Dimitrio, Su, Guoping, Suh, Judy M., Villaseñor, Armando G., Welch, Michael, Zhang, Fang-Jie, Klumpp, Klaus
Published in ChemMedChem (12.01.2009)
Published in ChemMedChem (12.01.2009)
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AG10, A Novel, Potent and Selective Transthyretin Stabilizer, is Well Tolerated at Doses Resulting in Target Therapeutic Blood Levels, and Demonstrates Clinical Proof-of-Concept in Healthy Volunteers
Hellawell, Jennifer L., Rao, Satish, O'Reilly, Terry, Lumpkin, Rick, Jernelius, Jesper, Gretler, Daniel, Sinha, Uma, Fox, Jonathan C.
Published in Journal of cardiac failure (01.08.2018)
Published in Journal of cardiac failure (01.08.2018)
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Journal Article
SYK POLYMORPHS OF SYK INHIBITORS
ELFORD TIM G, FUNG PETER CHEE CHU, HARTMEIER PAUL ROBERT, MORRISON HENRY, JERNELIUS JESPER ALEXIS
Year of Publication 27.05.2022
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Year of Publication 27.05.2022
Patent
SYK 억제제의 다형체
ELFORD TIM G, FUNG PETER CHEE CHU, HARTMEIER PAUL ROBERT, MORRISON HENRY, JERNELIUS JESPER ALEXIS
Year of Publication 28.04.2020
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Year of Publication 28.04.2020
Patent
The First Polymer-Supported and Recyclable Chiral Catalyst for Enantioselective Olefin Metathesis
Hultzsch, Kai C., Jernelius, Jesper A., Hoveyda, Amir H., Schrock, Richard R.
Published in Angewandte Chemie (15.02.2002)
Published in Angewandte Chemie (15.02.2002)
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