Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors
Tarr, James C., Salovich, James M., Aichinger, Martin, Jeon, KyuOk, Veerasamy, Nagarathanam, Sensintaffar, John L., Arnhof, Heribert, Samwer, Matthias, Christov, Plamen P., Kim, Kwangho, Wunberg, Tobias, Schweifer, Norbert, Trapani, Francesca, Arnold, Allison, Martin, Florian, Zhao, Bin, Miriyala, Nagaraju, Sgubin, Danielle, Fogarty, Stuart, Moore, William J., Stott, Gordon M., Olejniczak, Edward T., Engelhardt, Harald, Rudolph, Dorothea, Lee, Taekyu, McConnell, Darryl B., Fesik, Stephen W.
Published in Journal of medicinal chemistry (05.08.2024)
Published in Journal of medicinal chemistry (05.08.2024)
Get full text
Journal Article
Abstract 2562: Role of MET signaling in cetuximab resistance and generation of an imaging biomarker to identify MET-driven cetuximab resistance in colorectal cancer
Jones, Vivian T., Graves-Deal, Ramona, Jeon, KyuOK, Rosenberg, Adam J., Cao, Zheng, Bogatcheva, Galina T., Harmych, Sarah J., Higginbotham, James N., Kim, Kwangho, Janetka, James W., Sulikowski, Gary A., Singh, Bhuminder
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
치환된 인돌 MCL-1 억제제
JEON KYUOK, SHAW SUBRATA, OLEJNICZAK EDWARD T, VEERASAMY NAGARATHANAM, CHRISTOV PLAMEN P, TARR JAMES C, ZHAO BIN, LEE TAEKYU, SALOVICH JAMES M, KIM KWANGHO, FESIK STEPHEN W, BIAN ZHIGUO
Year of Publication 30.10.2018
Get full text
Year of Publication 30.10.2018
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
FESIK, STEPHEN W, BIAN, ZHIGUO, JEON, KYUOK, VEERASAMY, NAGARATHANAM, ZHAO, BIN, CHRISTOV, PLAMEN P, TARR, JAMES C, LEE, TAEKYU, KIM, KWANGHO, SALOVICH, JAMES M, OLEJNICZAK, EDWARD T, SHAW, SUBRATA
Year of Publication 27.02.2024
Get full text
Year of Publication 27.02.2024
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
Jeon, Kyuok, Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Veerasamy, Nagarathanam, Kim, Kwangho, Zhao, Bin, Bian, Zhiguo, Olejniczak, Edward T, Christov, Plamen P, Salovich, James M, Shaw, Subrata
Year of Publication 21.02.2024
Get full text
Year of Publication 21.02.2024
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
Jeon, Kyuok, Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Veerasamy, Nagarathanam, Kim, Kwangho, Zhao, Bin, Bian, Zhiguo, Olejniczak, Edward T, Christov, Plamen P, Salovich, James M, Shaw, Subrata
Year of Publication 20.12.2023
Get full text
Year of Publication 20.12.2023
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
Jeon, KyuOk, Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Veerasamy, Nagarathanam, Kim, Kwangho, Zhao, Bin, Bian, Zhiguo, Olejniczak, Edward T, Christov, Plamen P, Salovich, James M, Shaw, Subrata
Year of Publication 19.10.2023
Get full text
Year of Publication 19.10.2023
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
LEE, Taekyu, SALOVICH, James, M, CHRISTOV, Plamen, P, FESIK, Stephen, W, KIM, Kwangho, SHAW, Subrata, TARR, James, C, ZHAO, Bin, VEERASAMY, Nagarathanam, OLEJNICZAK, Edward, T, JEON, Kyuok, BIAN, Zhiguo
Year of Publication 23.08.2023
Get full text
Year of Publication 23.08.2023
Patent
Substituted indole Mcl-1 inhibitors
Jeon, KyuOk, Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Veerasamy, Nagarathanam, Kim, Kwangho, Zhao, Bin, Bian, Zhiguo, Olejniczak, Edward T, Christov, Plamen P, Salovich, James M, Shaw, Subrata
Year of Publication 07.03.2023
Get full text
Year of Publication 07.03.2023
Patent
Substituted indole Mcl-1 inhibitors
Jeon, Kyuok, Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Veerasamy, Nagarathanam, Kim, Kwangho, Zhao, Bin, Bian, Zhiguo, Olejniczak, Edward T, Christov, Plamen P, Salovich, James M, Shaw, Subrata
Year of Publication 04.11.2021
Get full text
Year of Publication 04.11.2021
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
Jeon, KyuOk, Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Veerasamy, Nagarathanam, Kim, Kwangho, Zhao, Bin, Bian, Zhiguo, Olejniczak, Edward T, Christov, Plamen P, Salovich, James M, Shaw, Subrata
Year of Publication 16.09.2021
Get full text
Year of Publication 16.09.2021
Patent
WDR5-MLL1 inhibitors and modulators
Jeon, KyuOk, Gogliotti, Rocco D, Fesik, Stephen W, Han, Changho, Lee, Taekyu, Stauffer, Shaun R, Mills, Jonathan J, Alvarado, Joseph R, Salovich, James M, Macdonald, Jonathan D, Meyers, Kenneth M
Year of Publication 20.10.2020
Get full text
Year of Publication 20.10.2020
Patent
WDR5-MLL1 INHIBITORS AND MODULATORS
Jeon, KyuOk, Gogliotti, Rocco D, Fesik, Stephen W, Han, Changho, Lee, Taekyu, Stauffer, Shaun R, Mills, Jonathan J, Alvarado, Joseph R, Salovich, James M, Macdonald, Jonathan D, Meyers, Kenneth M
Year of Publication 20.02.2020
Get full text
Year of Publication 20.02.2020
Patent
WDR5 inhibitors and modulators
Wang, Feng, Jeon, KyuOk, Gogliotti, Rocco D, Tansey, William P, Fesik, Stephen W, Stauffer, Shaun R, Olejniczak, Edward T, Phan, Jason
Year of Publication 25.12.2018
Get full text
Year of Publication 25.12.2018
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
LEE, Taekyu, SALOVICH, James, M, CHRISTOV, Plamen, P, FESIK, Stephen, W, KIM, Kwangho, SHAW, Subrata, TARR, James, C, ZHAO, Bin, VEERASAMY, Nagarathanam, OLEJNICZAK, Edward, T, JEON, Kyuok, BIAN, Zhiguo
Year of Publication 14.08.2019
Get full text
Year of Publication 14.08.2019
Patent
Compostos inibidores de mcl-1 indol substituídos, composição farmacêutica compreendendo ditos compostos e usos terapêuticos dos mesmos
JEON KYUOK, PLAMEN P. CHRISTOV, SHAW SUBRATA, VEERASAMY NAGARATHANAM, ZHAO BIN, JAMES M. SALOVICH, EDWARD T. OLEJNICZAK, LEE TAEKYU, KIM KWANGHO, STEPHEN W. FESIK, JAMES C. TARR, BIAN ZHIGUO
Year of Publication 15.02.2024
Get full text
Year of Publication 15.02.2024
Patent
WDR5 INHIBITORS AND MODULATORS
Fesik Stephen W, Tansey William P, Stauffer Shaun R, Phan Jason, Olejniczak Edward T, Jeon KyuOk, Gogliotti Rocco D, Wang Feng
Year of Publication 29.03.2018
Get full text
Year of Publication 29.03.2018
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
LEE, Taekyu, SALOVICH, James, M, CHRISTOV, Plamen, P, FESIK, Stephen, W, KIM, Kwangho, SHAW, Subrata, TARR, James, C, ZHAO, Bin, VEERASAMY, Nagarathanam, OLEJNICZAK, Edward, T, JEON, Kyuok, BIAN, Zhiguo
Year of Publication 04.02.2019
Get full text
Year of Publication 04.02.2019
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
LEE, Taekyu, SALOVICH, James, M, CHRISTOV, Plamen, P, FESIK, Stephen, W, KIM, Kwangho, SHAW, Subrata, TARR, James, C, ZHAO, Bin, VEERASAMY, Nagarathanam, OLEJNICZAK, Edward, T, JEON, Kyuok, BIAN, Zhiguo
Year of Publication 09.01.2019
Get full text
Year of Publication 09.01.2019
Patent
Substituted indole Mcl-1 inhibitors
Jeon, Kyuok, Fesik, Stephen W, Tarr, James C, Lee, Taekyu, Veerasamy, Nagarathanam, Kim, Kwangho, Zhao, Bin, Bian, Zhiguo, Olejniczak, Edward T, Christov, Plamen P, Salovich, James M, Shaw, Subrata
Year of Publication 06.09.2018
Get full text
Year of Publication 06.09.2018
Patent