Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism
Gooding, Jessica R., Jensen, Mette V., Dai, Xiaoqing, Wenner, Brett R., Lu, Danhong, Arumugam, Ramamani, Ferdaoussi, Mourad, MacDonald, Patrick E., Newgard, Christopher B.
Published in Cell reports (Cambridge) (06.10.2015)
Published in Cell reports (Cambridge) (06.10.2015)
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Journal Article
Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors
Tessem, Jeffery S., Moss, Larry G., Chao, Lily C., Arlotto, Michelle, Lu, Danhong, Jensen, Mette V., Stephens, Samuel B., Tontonoz, Peter, Hohmeier, Hans E., Newgard, Christopher B.
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
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Journal Article
A Pyruvate Cycling Pathway Involving Cytosolic NADP-dependent Isocitrate Dehydrogenase Regulates Glucose-stimulated Insulin Secretion
Ronnebaum, Sarah M., Ilkayeva, Olga, Burgess, Shawn C., Joseph, Jamie W., Lu, Danhong, Stevens, Robert D., Becker, Thomas C., Sherry, A. Dean, Newgard, Christopher B., Jensen, Mette V.
Published in The Journal of biological chemistry (13.10.2006)
Published in The Journal of biological chemistry (13.10.2006)
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Journal Article
The Mitochondrial Citrate/Isocitrate Carrier Plays a Regulatory Role in Glucose-stimulated Insulin Secretion
Joseph, Jamie W., Jensen, Mette V., Ilkayeva, Olga, Palmieri, Ferdinando, Alárcon, Cristina, Rhodes, Christopher J., Newgard, Christopher B.
Published in The Journal of biological chemistry (24.11.2006)
Published in The Journal of biological chemistry (24.11.2006)
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Journal Article
The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets
Li, Xiaoyan Nina, Herrington, James, Petrov, Aleksandr, Ge, Lan, Eiermann, George, Xiong, Yusheng, Jensen, Mette V, Hohmeier, Hans E, Newgard, Christopher B, Garcia, Maria L, Wagner, Michael, Zhang, Bei B, Thornberry, Nancy A, Howard, Andrew D, Kaczorowski, Gregory J, Zhou, Yun-Ping
Published in The Journal of pharmacology and experimental therapeutics (01.02.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2013)
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Journal Article
Control of Voltage-gated Potassium Channel Kv2.2 Expression by Pyruvate-Isocitrate Cycling Regulates Glucose-stimulated Insulin Secretion
Jensen, Mette V., Haldeman, Jonathan M., Zhang, Hengtao, Lu, Danhong, Huising, Mark O., Vale, Wylie W., Hohmeier, Hans E., Rosenberg, Paul, Newgard, Christopher B.
Published in The Journal of biological chemistry (09.08.2013)
Published in The Journal of biological chemistry (09.08.2013)
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Journal Article
Silencing of Cytosolic or Mitochondrial Isoforms of Malic Enzyme Has No Effect on Glucose-stimulated Insulin Secretion from Rodent Islets
Ronnebaum, Sarah M., Jensen, Mette V., Hohmeier, Hans E., Burgess, Shawn C., Zhou, Yun-Ping, Qian, Su, MacNeil, Douglas, Howard, Andrew, Thornberry, Nancy, Ilkayeva, Olga, Lu, Danhong, Sherry, A. Dean, Newgard, Christopher B.
Published in The Journal of biological chemistry (24.10.2008)
Published in The Journal of biological chemistry (24.10.2008)
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Journal Article
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion
Zhang, Guo-Fang, Jensen, Mette V., Gray, Sarah M., El, Kimberley, Wang, You, Lu, Danhong, Becker, Thomas C., Campbell, Jonathan E., Newgard, Christopher B.
Published in Cell metabolism (06.04.2021)
Published in Cell metabolism (06.04.2021)
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Journal Article
Biochemical Mechanism of Lipid-induced Impairment of Glucose-stimulated Insulin Secretion and Reversal with a Malate Analogue
Boucher, Anne, Lu, Danhong, Burgess, Shawn C., Telemaque-Potts, Sabine, Jensen, Mette V., Mulder, Hindrik, Wang, May-Yun, Unger, Roger H., Sherry, A. Dean, Newgard, Christopher B.
Published in The Journal of biological chemistry (25.06.2004)
Published in The Journal of biological chemistry (25.06.2004)
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Journal Article
Metabolomics applied to the pancreatic islet
Gooding, Jessica R., Jensen, Mette V., Newgard, Christopher B.
Published in Archives of biochemistry and biophysics (01.01.2016)
Published in Archives of biochemistry and biophysics (01.01.2016)
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Journal Article
Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells
Ferdaoussi, Mourad, Dai, Xiaoqing, Jensen, Mette V, Wang, Runsheng, Peterson, Brett S, Huang, Chao, Ilkayeva, Olga, Smith, Nancy, Miller, Nathanael, Hajmrle, Catherine, Spigelman, Aliya F, Wright, Robert C, Plummer, Gregory, Suzuki, Kunimasa, Mackay, James P, van de Bunt, Martijn, Gloyn, Anna L, Ryan, Terence E, Norquay, Lisa D, Brosnan, M Julia, Trimmer, Jeff K, Rolph, Timothy P, Kibbey, Richard G, Manning Fox, Jocelyn E, Colmers, William F, Shirihai, Orian S, Neufer, P Darrell, Yeh, Edward T H, Newgard, Christopher B, MacDonald, Patrick E
Published in The Journal of clinical investigation (01.10.2015)
Published in The Journal of clinical investigation (01.10.2015)
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Journal Article
The Mitochondrial 2-Oxoglutarate Carrier Is Part of a Metabolic Pathway That Mediates Glucose- and Glutamine-stimulated Insulin Secretion
Odegaard, Matthew L., Joseph, Jamie W., Jensen, Mette V., Lu, Danhong, Ilkayeva, Olga, Ronnebaum, Sarah M., Becker, Thomas C., Newgard, Christopher B.
Published in The Journal of biological chemistry (28.05.2010)
Published in The Journal of biological chemistry (28.05.2010)
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Journal Article
Compensatory Responses to Pyruvate Carboxylase Suppression in Islet β-Cells: PRESERVATION OF GLUCOSE-STIMULATED INSULIN SECRETION
Jensen, Mette V, Joseph, Jamie W, Ilkayeva, Olga, Burgess, Shawn, Lu, Danhong, Ronnebaum, Sarah M, Odegaard, Matthew, Becker, Thomas C, Sherry, A. Dean, Newgard, Christopher B
Published in The Journal of biological chemistry (04.08.2006)
Published in The Journal of biological chemistry (04.08.2006)
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Journal Article
13C NMR Isotopomer Analysis Reveals a Connection between Pyruvate Cycling and Glucose-Stimulated Insulin Secretion (GSIS)
Lu, Danhong, Mulder, Hindrik, Zhao, Piyu, Burgess, Shawn C., Jensen, Mette V., Kamzolova, Svetlana, Newgard, Christopher B., Sherry, A. Dean
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2002)
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Journal Article
Nkx6.1 regulates islet [Beta]-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors
Tessem, Jeffery S, Moss, Larry G, Chao, Lily C, Arlotto, Michelle, Lu, Danhong, Jensen, Mette V, Stephens, Samuel B, Tontonoz, Peter, Hohmeier, Hans E, Newgard, Christopher B
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
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Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Journal Article
Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional [Beta] cells
Ferdaoussi, Mourad, Dai, Xiaoqing, Jensen, Mette V, Wang, Runsheng, Peterson, Brett S, Huang, Chao, Ilkayeva, Olga, Smith, Nancy, Miller, Nathanael, Hajmrle, Catherine, Spigelman, Aliya F, Wright, Robert C, Plummer, Gregory, Suzuki, Kunimasa, Mackay, James P, van de Bunt, Martijn, Gloyn, Anna L, Ryan, Terence E, Norquay, Lisa D, Brosnan, M Julia, Trimmer, Jeff K, Rolph, Timothy P, Kibbey, Richard G, Fox, Jocelyn E Manning, Colmers, William F, Shirihai, Orian S, Neufer, P Darrell, Yeh, Edward T H, Newgard, Christopher B, MacDonald, Patrick E
Published in The Journal of clinical investigation (01.10.2015)
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Published in The Journal of clinical investigation (01.10.2015)
Journal Article
Metabolic Regulation of Insulin Secretion: Importance of Pyruvate Carboxylase
Jensen, Mette V, Becker, Thomas C, Newgard, Christopher B
Published in Diabetes (New York, N.Y.) (01.06.2005)
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Published in Diabetes (New York, N.Y.) (01.06.2005)
Journal Article