Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix
Jennings, Laura K, Storek, Kelly M, Ledvina, Hannah E, Coulon, Charlène, Marmont, Lindsey S, Sadovskaya, Irina, Secor, Patrick R, Tseng, Boo Shan, Scian, Michele, Filloux, Alain, Wozniak, Daniel J, Howell, P Lynne, Parsek, Matthew R
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
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Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies
Jennings, Laura K., Dreifus, Julia E., Reichhardt, Courtney, Storek, Kelly M., Secor, Patrick R., Wozniak, Daniel J., Hisert, Katherine B., Parsek, Matthew R.
Published in Cell reports (Cambridge) (23.02.2021)
Published in Cell reports (Cambridge) (23.02.2021)
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Journal Article
ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa
Jones, Christopher J, Newsom, David, Kelly, Benjamin, Irie, Yasuhiko, Jennings, Laura K, Xu, Binjie, Limoli, Dominique H, Harrison, Joe J, Parsek, Matthew R, White, Peter, Wozniak, Daniel J
Published in PLoS pathogens (01.03.2014)
Published in PLoS pathogens (01.03.2014)
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Bacterial cyclic diguanylate signaling networks sense temperature
Almblad, Henrik, Randall, Trevor E., Liu, Fanny, Leblanc, Katherine, Groves, Ryan A., Kittichotirat, Weerayuth, Winsor, Geoffrey L., Fournier, Nicolas, Au, Emily, Groizeleau, Julie, Rich, Jacquelyn D., Lou, Yuefei, Granton, Elise, Jennings, Laura K., Singletary, Larissa A., Winstone, Tara M. L., Good, Nathan M., Bumgarner, Roger E., Hynes, Michael F., Singh, Manu, Stietz, Maria Silvina, Brinkman, Fiona S. L., Kumar, Ayush, Brassinga, Ann Karen Cornelia, Parsek, Matthew R., Tseng, Boo Shan, Lewis, Ian A., Yipp, Bryan G., MacCallum, Justin L., Harrison, Joe Jonathan
Published in Nature communications (31.03.2021)
Published in Nature communications (31.03.2021)
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Journal Article
Pf Bacteriophage and Their Impact on Pseudomonas Virulence, Mammalian Immunity, and Chronic Infections
Secor, Patrick R, Burgener, Elizabeth B, Kinnersley, M, Jennings, Laura K, Roman-Cruz, Valery, Popescu, Medeea, Van Belleghem, Jonas D, Haddock, Naomi, Copeland, Conner, Michaels, Lia A, de Vries, Christiaan R, Chen, Qingquan, Pourtois, Julie, Wheeler, Travis J, Milla, Carlos E, Bollyky, Paul L
Published in Frontiers in immunology (21.02.2020)
Published in Frontiers in immunology (21.02.2020)
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Journal Article
A Filamentous Bacteriophage Protein Inhibits Type IV Pili To Prevent Superinfection of Pseudomonas aeruginosa
Schmidt, Amelia K, Fitzpatrick, Alexa D, Schwartzkopf, Caleb M, Faith, Dominick R, Jennings, Laura K, Coluccio, Alison, Hunt, Devin J, Michaels, Lia A, Hargil, Aviv, Chen, Qingquan, Bollyky, Paul L, Dorward, David W, Wachter, Jenny, Rosa, Patricia A, Maxwell, Karen L, Secor, Patrick R
Published in mBio (22.02.2022)
Published in mBio (22.02.2022)
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Polyamines and linear DNA mediate bacterial threat assessment of bacteriophage infection
de Mattos, Camilla D, Faith, Dominick R, Nemudryi, Artem A, Schmidt, Amelia K, Bublitz, DeAnna C, Hammond, Lauren, Kinnersley, Margie A, Schwartzkopf, Caleb M, Robinson, Autumn J, Joyce, Alex, Michaels, Lia A, Brzozowski, Robert S, Coluccio, Alison, Xing, Denghui David, Uchiyama, Jumpei, Jennings, Laura K, Eswara, Prahathees, Wiedenheft, Blake, Secor, Patrick R
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2023)
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Journal Article
The Depletion Mechanism Actuates Bacterial Aggregation by Exopolysaccharides and Determines Species Distribution & Composition in Bacterial Aggregates
Secor, Patrick R, Michaels, Lia A, Bublitz, DeAnna C, Jennings, Laura K, Singh, Pradeep K
Published in Frontiers in cellular and infection microbiology (16.06.2022)
Published in Frontiers in cellular and infection microbiology (16.06.2022)
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Journal Article
Proteomic and Transcriptomic Analyses Reveal Genes Upregulated by cis-Dichloroethene in Polaromonas sp. Strain JS666
Jennings, Laura K, Chartrand, Michelle M.G, Lacrampe-Couloume, Georges, Lollar, Barbara Sherwood, Spain, Jim C, Gossett, James M
Published in Applied and Environmental Microbiology (01.06.2009)
Published in Applied and Environmental Microbiology (01.06.2009)
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Journal Article
Entropically driven aggregation of bacteria by host polymers promotes antibiotic tolerance in Pseudomonas aeruginosa
Secor, Patrick R., Michaels, Lia A., Ratjen, Anina, Jennings, Laura K., Singh, Pradeep K.
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
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Journal Article
Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression
Secor, Patrick R, Jennings, Laura K, James, Garth A, Kirker, Kelly R, Pulcini, Elinor Delancey, McInnerney, Kate, Gerlach, Robin, Livinghouse, Tom, Hilmer, Jonathan K, Bothner, Brian, Fleckman, Philip, Olerud, John E, Stewart, Philip S
Published in PloS one (13.07.2012)
Published in PloS one (13.07.2012)
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Journal Article
Biofilm assembly becomes crystal clear - filamentous bacteriophage organize the Pseudomonas aeruginosa biofilm matrix into a liquid crystal
Secor, Patrick R, Jennings, Laura K, Michaels, Lia A, Sweere, Johanna M, Singh, Pradeep K, Parks, William C, Bollyky, Paul L
Published in Microbial cell (31.12.2015)
Published in Microbial cell (31.12.2015)
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Journal Article
Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis
Burgener, Elizabeth B, Sweere, Johanna M, Bach, Michelle S, Secor, Patrick R, Haddock, Naomi, Jennings, Laura K, Marvig, Rasmus L, Johansen, Helle Krogh, Rossi, Elio, Cao, Xiou, Tian, Lu, Nedelec, Laurence, Molin, Søren, Bollyky, Paul L, Milla, Carlos E
Published in Science translational medicine (17.04.2019)
Published in Science translational medicine (17.04.2019)
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Journal Article
Filamentous Bacteriophage Produced by Pseudomonas aeruginosa Alters the Inflammatory Response and Promotes Noninvasive Infection In Vivo
Secor, Patrick R, Michaels, Lia A, Smigiel, Kate S, Rohani, Maryam G, Jennings, Laura K, Hisert, Katherine B, Arrigoni, Allison, Braun, Kathleen R, Birkland, Timothy P, Lai, Ying, Hallstrand, Teal S, Bollyky, Paul L, Singh, Pradeep K, Parks, William C
Published in Infection and immunity (01.01.2017)
Published in Infection and immunity (01.01.2017)
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Journal Article
Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms
Baker, Perrin, Hill, Preston J, Snarr, Brendan D, Alnabelseya, Noor, Pestrak, Matthew J, Lee, Mark J, Jennings, Laura K, Tam, John, Melnyk, Roman A, Parsek, Matthew R, Sheppard, Donald C, Wozniak, Daniel J, Howell, P Lynne
Published in Science advances (01.05.2016)
Published in Science advances (01.05.2016)
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Journal Article
Hexavalent chromium reduction by Cellulomonas sp. strain ES6: the influence of carbon source, iron minerals, and electron shuttling compounds
Field, Erin K., Gerlach, Robin, Viamajala, Sridhar, Jennings, Laura K., Peyton, Brent M., Apel, William A.
Published in Biodegradation (Dordrecht) (01.06.2013)
Published in Biodegradation (Dordrecht) (01.06.2013)
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Journal Article
Correction: Phevalin (aureusimine B)Production by Staphylococcus aureus Biofilm and Impacts on Human Keratinocyte Gene Expression
Secor, Patrick R., Jennings, Laura K., James, Garth A., Kirker, Kelly R., Pulcini, Elinor deLancey, McInnerney, Kate, Gerlach, Robin, Livinghouse, Tom, Hilmer, Jonathan K., Bothner, Brian, Fleckman, Philip, Olerud, John E., Stewart, Philip S.
Published in PloS one (11.10.2012)
Published in PloS one (11.10.2012)
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Journal Article
Pel is a cationic exopolysaccharide that cross-links extracellular DNA in thePseudomonas aeruginosabiofilm matrix
Jennings, Laura K., Storek, Kelly M., Ledvina, Hannah E., Coulon, Charlène, Marmont, Lindsey S., Sadovskaya, Irina, Secor, Patrick R., Tseng, Boo Shan, Scian, Michele, Filloux, Alain, Wozniak, Daniel J., Howell, P. Lynne, Parsek, Matthew R.
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
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Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
Journal Article
ChIP-Seq and RNA-Seq Reveal an AmrZ-Mediated Mechanism for Cyclic di-GMP Synthesis and Biofilm Development by Pseudomonas aeruginosa: e1003984
Jones, Christopher J, Newsom, David, Kelly, Benjamin, Irie, Yasuhiko, Jennings, Laura K, Xu, Binjie, Limoli, Dominique H, Harrison, Joe J, Parsek, Matthew R, White, Peter, Wozniak, Daniel J
Published in PLoS pathogens (01.03.2014)
Published in PLoS pathogens (01.03.2014)
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