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Hendrick, Charles E., Jorgensen, Jeff R., Chaudhry, Charu, Strambeanu, Iulia I., Brazeau, Jean-Francois, Schiffer, Jamie, Shi, Zhicai, Venable, Jennifer D., Wolkenberg, Scott E.
Published in ACS medicinal chemistry letters (14.07.2022)
Published in ACS medicinal chemistry letters (14.07.2022)
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Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators
Tichenor, Mark S, Thurmond, Robin L, Venable, Jennifer D, Savall, Brad M
Published in Journal of medicinal chemistry (24.09.2015)
Published in Journal of medicinal chemistry (24.09.2015)
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Discovery of Highly Potent and Selective IRAK1 Degraders to Probe Scaffolding Functions of IRAK1 in ABC DLBCL
Fu, Liqiang, Zhang, Jing, Shen, Bin, Kong, Linglong, Liu, Yingtao, Tu, Wangyang, Wang, Wenqian, Cai, Xin, Wang, Xiaotao, Cheng, Na, Xia, Mingxuan, Zhou, Tianyuan, Liu, Qian, Xu, Yanping, Yang, Jennifer, Gavine, Paul, Philippar, Ulrike, Attar, Ricardo, Edwards, James P, Venable, Jennifer D, Dai, Xuedong
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation
Babbe, Holger, Sundberg, Thomas B, Tichenor, Mark, Seierstad, Mark, Bacani, Genesis, Berstler, James, Chai, Wenying, Chang, Leon, Chung, De Michael, Coe, Kevin, Collins, Bernard, Finley, Michael, Guletsky, Alexander, Lemke, Christopher T, Mak, Puiying A, Mathur, Ashok, Mercado-Marin, Eduardo V, Metkar, Shailesh, Raymond, Donald D, Rives, Marie-Laure, Rizzolio, Michele, Shaffer, Paul L, Smith, Russell, Smith, Jacqueline, Steele, Ruth, Steffens, Helena, Suarez, Javier, Tian, Gaochao, Majewski, Nathan, Volak, Laurie P, Wei, Jianmei, Desai, Prerak T, Ong, Luvena L, Koudriakova, Tatiana, Goldberg, Steven D, Hirst, Gavin, Kaushik, Virendar K, Ort, Tatiana, Seth, Nilufer, Graham, Daniel B, Plevy, Scott, Venable, Jennifer D, Xavier, Ramnik J, Towne, Jennifer E
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2024)
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Development of small molecule inhibitors of natural killer group 2D receptor (NKG2D)
Wang, Jocelyn, Nakafuku, Kohki M., Ziff, Jeannie, Gelin, Christine F., Gholami, Hadi, Thompson, Aaron A., Karpowich, Nathan K., Limon, Luis, Coate, Heather R., Damm-Ganamet, Kelly L., Shih, Amy Y., Grant, Joanna C., Côte, Marjorie, Mak, Puiying A., Pascual, Heather A., Rives, Marie-Laure, Edwards, James P., Venable, Jennifer D., Venkatesan, Hariharan, Shi, Zhicai, Allen, Samantha J., Sharma, Sujata, Kung, Pei-Pei, Shireman, Brock T.
Published in Bioorganic & medicinal chemistry letters (15.11.2023)
Published in Bioorganic & medicinal chemistry letters (15.11.2023)
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Identification of small-molecule protein-protein interaction inhibitors for NKG2D
Thompson, Aaron A, Harbut, Michael B, Kung, Pei-Pei, Karpowich, Nathan K, Branson, Jeffrey D, Grant, Joanna C, Hagan, Deborah, Pascual, Heather A, Bai, Guoyun, Zavareh, Reza Beheshti, Coate, Heather R, Collins, Bernard C, Côte, Marjorie, Gelin, Christine F, Damm-Ganamet, Kelly L, Gholami, Hadi, Huff, Adam R, Limon, Luis, Lumb, Kevin J, Mak, Puiying A, Nakafuku, Kohki M, Price, Edmund V, Shih, Amy Y, Tootoonchi, Mandana, Vellore, Nadeem A, Wang, Jocelyn, Wei, Na, Ziff, Jeannie, Berger, Scott B, Edwards, James P, Gardet, Agnès, Sun, Siquan, Towne, Jennifer E, Venable, Jennifer D, Shi, Zhicai, Venkatesan, Hariharan, Rives, Marie-Laure, Sharma, Sujata, Shireman, Brock T, Allen, Samantha J
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2023)
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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease
Leonard, Kristi A, Madge, Lisa A, Krawczuk, Paul J, Wang, Aihua, Kreutter, Kevin D, Bacani, Genesis M, Chai, Wenying, Smith, Russell C, Tichenor, Mark S, Harris, Michael C, Malaviya, Ravi, Seierstad, Mark, Johnson, Marguerite E, Venable, Jennifer D, Kim, Suzie, Hirst, Gavin C, Mathur, Ashok S, Rao, Tadimeti S, Edwards, James P, Rizzolio, Michele C, Koudriakova, Tatiana
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
Tichenor, Mark S., Wiener, John J. M., Rao, Navin L., Bacani, Genesis M., Wei, Jianmei, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D., Chang, Leon, Clancy, Kathleen W., Murrey, Heather E., Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J., Wu, Jiejun, Rui, Haopeng, Sepassi, Kia, Gaudiano, Marcello, Bekkers, Mariette, Cornelissen, Ivo, Packman, Kathryn, Seierstad, Mark, Xiouras, Christos, Bembenek, Scott D., Alexander, Richard, Milligan, Cynthia, Balasubramanian, Sriram, Lebsack, Alec D., Venable, Jennifer D., Philippar, Ulrike, Edwards, James P., Hirst, Gavin
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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Journal Article
Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity
Tichenor, Mark S, Wiener, John J. M, Rao, Navin L, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D, Bacani, Genesis M, Wei, Jianmei, Chang, Leon, Murrey, Heather E, Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J, Wu, JieJun, Seierstad, Mark, Bembenek, Scott D, Leonard, Kristi A, Lebsack, Alec D, Venable, Jennifer D, Edwards, James P
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Small molecule inhibitors of phosphoinositide 3-kinase (PI3K) delta and gamma
Ameriks, Michael K, Venable, Jennifer D
Published in Current topics in medicinal chemistry (01.05.2009)
Published in Current topics in medicinal chemistry (01.05.2009)
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The histamine H4 receptor in autoimmune disease
Zhang, Mai, Venable, Jennifer D, Thurmond, Robin L
Published in Expert opinion on investigational drugs (01.11.2006)
Published in Expert opinion on investigational drugs (01.11.2006)
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The First Potent and Selective Non-Imidazole Human Histamine H4 Receptor Antagonists
Jablonowski, Jill A, Grice, Cheryl A, Chai, Wenying, Dvorak, Curt A, Venable, Jennifer D, Kwok, Annette K, Ly, Kiev S, Wei, Jianmei, Baker, Sherry M, Desai, Pragnya J, Jiang, Wen, Wilson, Sandy J, Thurmond, Robin L, Karlsson, Lars, Edwards, James P, Lovenberg, Timothy W, Carruthers, Nicholas I
Published in Journal of medicinal chemistry (11.09.2003)
Published in Journal of medicinal chemistry (11.09.2003)
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Preparation and Biological Evaluation of Indole, Benzimidazole, and Thienopyrrole Piperazine Carboxamides: Potent Human Histamine H4 Antagonists
Venable, Jennifer D, Cai, Hui, Chai, Wenying, Dvorak, Curt A, Grice, Cheryl A, Jablonowski, Jill A, Shah, Chandra R, Kwok, Annette K, Ly, Kiev S, Pio, Barbara, Wei, Jianmei, Desai, Pragnya J, Jiang, Wen, Nguyen, Steven, Ling, Ping, Wilson, Sandy J, Dunford, Paul J, Thurmond, Robin L, Lovenberg, Timothy W, Karlsson, Lars, Carruthers, Nicholas I, Edwards, James P
Published in Journal of medicinal chemistry (29.12.2005)
Published in Journal of medicinal chemistry (29.12.2005)
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Some reactions of persistent benzofuranone radicals related to the ‘old’ diazonamide structure
Magnus, Philip, Venable (nee Kreisberg), Jennifer D., Shen, Lan, Lynch, Vince
Published in Tetrahedron letters (01.01.2005)
Published in Tetrahedron letters (01.01.2005)
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Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands
Savall, Brad M., Edwards, James P., Venable, Jennifer D., Buzard, Daniel J., Thurmond, Robin, Hack, Michael, McGovern, Patricia
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
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POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE
CHEN WEI, BRAHMANANDA GHOSH, CHARLOTTE POOLEY DECKHUT, XIAO KUN, JAMES P EDWARDS, SCOTT D BEMBENEK, ZHANG FEIHUANG, NIDHI ARORA, JOSEPH KENT BARBAY, WEI JIANMEI, JENNIFER D VENABLE, CAI MIN, KEVIN D KREUTTER, ZHU YAOPING, WU YAO, GENESIS M BACANI, JOHN J M WIENER, LI GANG, MARK S TICHENOR
Year of Publication 13.05.2021
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Year of Publication 13.05.2021
Patent
Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease
Venable, Jennifer D, Ameriks, Michael K, Blevitt, Jonathan M, Thurmond, Robin L, Fung-Leung, Wai-Ping
Published in Recent patents on inflammation & allergy drug discovery (01.01.2010)
Published in Recent patents on inflammation & allergy drug discovery (01.01.2010)
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Journal Article
Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: Potent human histamine H-4 antagonists
Venable, JD, Cai, H, Chai, WY, Dvorak, CA, Grice, CA, Jablonowski, JA, Shah, CR, Kwok, AK, Ly, KS, Pio, B, Wei, JM, Desai, PJ, Jiang, W, Nguyen, S, Ling, P, Wilson, SJ, Dunford, PJ, Thurmond, RL, Lovenberg, TW, Karlsson, L, Carruthers, NI, Edwards, JP
Published in Journal of medicinal chemistry (29.12.2005)
Published in Journal of medicinal chemistry (29.12.2005)
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