A Synthetic Agonist at the Orphanin FQ/Nociceptin Receptor ORL1: Anxiolytic Profile in the Rat
Jenck, Francois, Wichmann, Juergen, Dautzenberg, Frank M., Moreau, Jean-Luc, Ouagazzal, Abdel M., Martin, James R., Lundstrom, Kenneth, Cesura, Andrea M., Poli, Sonia M., Roever, Stephan, Kolczewski, Sabine, Adam, Geo, Kilpatrick, Gavin
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2000)
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Journal Article
5-HT2C Receptor Agonists: Pharmacological Characteristics and Therapeutic Potential
Martin, J R, Bös, M, Jenck, F, Moreau, J, Mutel, V, Sleight, A J, Wichmann, J, Andrews, J S, Berendsen, H H, Broekkamp, C L, Ruigt, G S, Köhler, C, Delft, A M
Published in The Journal of pharmacology and experimental therapeutics (01.08.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1998)
Journal Article
Orphanin FQ Acts as an Anxiolytic to Attenuate Behavioral Responses to Stress
Jenck, F, Moreau, J L, Martin, J R, Kilpatrick, G J, Reinscheid, R K, Monsma, Jr, F J, Nothacker, H P, Civelli, O
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.1997)
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Journal Article
A combined pharmacological and genetic approach to investigate the role of orphanin FQ in learning and memory
Higgins, G. A., Kew, J. N. C., Richards, J. G., Takeshima, H., Jenck, F., Adam, G., Wichmann, J., Kemp, J. A., Grottick, A. J.
Published in The European journal of neuroscience (01.03.2002)
Published in The European journal of neuroscience (01.03.2002)
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Journal Article
Synthesis of (1S,3aS)-8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one, a potent and selective orphanin FQ (OFQ) receptor agonist with anxiolytic-like properties
Wichmann, Jürgen, Adam, Geo, Röver, Stephan, Hennig, Michael, Scalone, Michelangelo, Cesura, Andrea M, Dautzenberg, Frank M, Jenck, François
Published in European journal of medicinal chemistry (01.09.2000)
Published in European journal of medicinal chemistry (01.09.2000)
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Journal Article
Spatial and associative learning deficits induced by neonatal excitotoxic hippocampal damage in rats: further evaluation of an animal model of schizophrenia
Le Pen, G, Grottick, A J, Higgins, G A, Martin, J R, Jenck, F, Moreau, J L
Published in Behavioural pharmacology (01.06.2000)
Published in Behavioural pharmacology (01.06.2000)
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Journal Article
High-Affinity, Non-Peptide Agonists for the ORL1 (Orphanin FQ/Nociceptin) Receptor
Röver, Stephan, Adam, Geo, Cesura, Andrea M, Galley, Guido, Jenck, François, Monsma, Frederick J, Wichmann, Jürgen, Dautzenberg, Frank M
Published in Journal of medicinal chemistry (06.04.2000)
Published in Journal of medicinal chemistry (06.04.2000)
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Journal Article
Influence of the selective ORL1 receptor agonist, Ro64-6198, on rodent neurological function
Higgins, G.A, Grottick, A.J, Ballard, T.M, Richards, J.G, Messer, J, Takeshima, H, Pauly-Evers, M, Jenck, F, Adam, G, Wichmann, J
Published in Neuropharmacology (01.07.2001)
Published in Neuropharmacology (01.07.2001)
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Novel Agonists of 5HT2C Receptors. Synthesis and Biological Evaluation of Substituted 2-(Indol-1-yl)-1-methylethylamines and 2-(Indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved Therapeutics for Obsessive Compulsive Disorder
Bös, Michael, Jenck, François, Martin, James R, Moreau, Jean-Luc, Sleight, Andrew J, Wichmann, Jürgen, Widmer, Ulrich
Published in Journal of medicinal chemistry (15.08.1997)
Published in Journal of medicinal chemistry (15.08.1997)
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Journal Article
Antidepressant treatment prevents chronic unpredictable mild stress-induced anhedonia as assessed by ventral tegmentum self-stimulation behavior in rats
Moreau, J.-L., Jenck, F., Martin, J.R., Mortas, P., Haefely, W.E.
Published in European neuropsychopharmacology (01.03.1992)
Published in European neuropsychopharmacology (01.03.1992)
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Journal Article
Novel Hexahydrospiro[piperidine-4,1‘-pyrrolo[3,4-c]pyrroles]: Highly Selective Small-Molecule Nociceptin/Orphanin FQ Receptor Agonists
Kolczewski, Sabine, Adam, Geo, Cesura, Andrea M, Jenck, François, Hennig, Michael, Oberhauser, Thomas, Poli, Sonia M, Rössler, Felix, Röver, Stephan, Wichmann, Jürgen, Dautzenberg, Frank M
Published in Journal of medicinal chemistry (16.01.2003)
Published in Journal of medicinal chemistry (16.01.2003)
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Journal Article
The orphanin receptor agonist RO 64-6198 does not induce place conditioning in rats
Le Pen, Gwenaëlle, Wichmann, Juergen, Moreau, Jean-Luc, Jenck, François
Published in Neuroreport (25.03.2002)
Published in Neuroreport (25.03.2002)
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Journal Article
OrphaninFQ: role in behavioral fear responses and vulnerability to stress?
Jenck, F, Ouagazzal, A M, Pauly-Evers, M, Moreau, J L
Published in Molecular psychiatry (01.11.2000)
Published in Molecular psychiatry (01.11.2000)
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