Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes
Gudernova, Iva, Vesela, Iva, Balek, Lukas, Buchtova, Marcela, Dosedelova, Hana, Kunova, Michaela, Pivnicka, Jakub, Jelinkova, Iva, Roubalova, Lucie, Kozubik, Alois, Krejci, Pavel
Published in Human molecular genetics (01.01.2016)
Published in Human molecular genetics (01.01.2016)
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DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism
Skender, Belma, Hofmanová, Jiřina, Slavík, Josef, Jelínková, Iva, Machala, Miroslav, Moyer, Mary Pat, Kozubík, Alois, Hyršlová Vaculová, Alena
Published in Biochimica et biophysica acta (01.09.2014)
Published in Biochimica et biophysica acta (01.09.2014)
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One reporter for in-cell activity profiling of majority of protein kinase oncogenes
Gudernova, Iva, Foldynova-Trantirkova, Silvie, Ghannamova, Barbora El, Fafilek, Bohumil, Varecha, Miroslav, Balek, Lukas, Hruba, Eva, Jonatova, Lucie, Jelinkova, Iva, Kunova Bosakova, Michaela, Trantirek, Lukas, Mayer, Jiri, Krejci, Pavel
Published in eLife (15.02.2017)
Published in eLife (15.02.2017)
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Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway
Jelínková, Iva, Šafaříková, Barbora, Vondálová Blanářová, Olga, Skender, Belma, Hofmanová, Jiřina, Sova, Petr, Moyer, Mary Pat, Kozubík, Alois, Kolář, Zdeněk, Ehrmann, Jiří, Hyršlová Vaculová, Alena
Published in Biochemical pharmacology (01.12.2014)
Published in Biochemical pharmacology (01.12.2014)
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An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome
Paige Taylor, S, Kunova Bosakova, Michaela, Varecha, Miroslav, Balek, Lukas, Barta, Tomas, Trantirek, Lukas, Jelinkova, Iva, Duran, Ivan, Vesela, Iva, Forlenza, Kimberly N, Martin, Jorge H, Hampl, Ales, Bamshad, Michael, Nickerson, Deborah, Jaworski, Margie L, Song, Jieun, Ko, Hyuk Wan, Cohn, Daniel H, Krakow, Deborah, Krejci, Pavel
Published in Human molecular genetics (15.09.2016)
Published in Human molecular genetics (15.09.2016)
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Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage
Buchtova, Marcela, Oralova, Veronika, Aklian, Anie, Masek, Jan, Vesela, Iva, Ouyang, Zhufeng, Obadalova, Tereza, Konecna, Zaneta, Spoustova, Tereza, Pospisilova, Tereza, Matula, Petr, Varecha, Miroslav, Balek, Lukas, Gudernova, Iva, Jelinkova, Iva, Duran, Ivan, Cervenkova, Iveta, Murakami, Shunichi, Kozubik, Alois, Dvorak, Petr, Bryja, Vitezslav, Krejci, Pavel
Published in Biochimica et biophysica acta (01.05.2015)
Published in Biochimica et biophysica acta (01.05.2015)
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Inhibition of vacuolar ATPase attenuates the TRAIL‐induced activation of caspase‐8 and modulates the trafficking of TRAIL receptosomes
Horova, Vladimira, Hradilova, Nada, Jelinkova, Iva, Koc, Michal, Svadlenka, Jan, Brazina, Jan, Klima, Martin, Slavik, Josef, Hyrslova Vaculova, Alena, Andera, Ladislav
Published in The FEBS journal (01.07.2013)
Published in The FEBS journal (01.07.2013)
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Modulation of genotoxic effects of benzo[a]pyrene in colon cancer cells by inhibition of Wnt/beta-catenin signaling
Vondracek, Jan, Kabatkova, Marketa, Jelinkova, Iva, Machala, Miroslav, Topinka, Jan, Milcova, Alena, Kozubik, Alois
Published in Toxicology letters (10.09.2014)
Published in Toxicology letters (10.09.2014)
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5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53
Akpinar, Birce, Bracht, Ethiene V, Reijnders, Dorin, Safarikova, Barbora, Jelinkova, Iva, Grandien, Alf, Vaculova, Alena Hyrslova, Zhivotovsky, Boris, Olsson, Magnus
Published in Oncotarget (22.12.2015)
Published in Oncotarget (22.12.2015)
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Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53
Akpinar, Birce, Bracht, Ethiene V, Reijnders, Dorin, Safarikova, Barbora, Jelinkova, Iva, Grandien, Alf, Vaculova, Alena Hyrslova, Zhivotovsky, Boris, Olsson, Magnus
Published in Oncotarget (01.11.2016)
Published in Oncotarget (01.11.2016)
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Journal Article
Inhibition of vacuolar ATP ase attenuates the TRAIL ‐induced activation of caspase‐8 and modulates the trafficking of TRAIL receptosomes
Horova, Vladimira, Hradilova, Nada, Jelinkova, Iva, Koc, Michal, Svadlenka, Jan, Brazina, Jan, Klima, Martin, Slavik, Josef, Hyrslova Vaculova, Alena, Andera, Ladislav
Published in The FEBS journal (01.07.2013)
Published in The FEBS journal (01.07.2013)
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Journal Article
Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53
Akpinar, Birce, Bracht, Ethiene V, Reijnders, Dorin, Safarikova, Barbora, Jelinkova, Iva, Grandien, Alf, Hyrslova Vaculova, Alena, Zhivotovsky, Boris, Olsson, Magnus
Published in Oncotarget (10.05.2016)
Published in Oncotarget (10.05.2016)
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Journal Article