Postexposure Protection of Guinea Pigs against a Lethal Ebola Virus Challenge Is Conferred by RNA Interference
Geisbert, Thomas W., Hensley, Lisa E., Kagan, Elliott, Yu, Erik Zhaoying, Geisbert, Joan B., Daddario-DiCaprio, Kathleen, Fritz, Elizabeth A., Jahrling, Peter B., McClintock, Kevin, Phelps, Janet R., Lee, Amy C. H., Judge, Adam, Jeffs, Lloyd B., MacLachlan, Ian
Published in The Journal of Infectious Diseases (15.06.2006)
Published in The Journal of Infectious Diseases (15.06.2006)
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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
Morrissey, David V, Lockridge, Jennifer A, Shaw, Lucinda, Blanchard, Karin, Jensen, Kristi, Breen, Wendy, Hartsough, Kimberly, Machemer, Lynn, Radka, Susan, Jadhav, Vasant, Vaish, Narendra, Zinnen, Shawn, Vargeese, Chandra, Bowman, Keith, Shaffer, Chris S, Jeffs, Lloyd B, Judge, Adam, MacLachlan, Ian, Polisky, Barry
Published in Nature biotechnology (01.08.2005)
Published in Nature biotechnology (01.08.2005)
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Journal Article
A scalable, extrusion-free method for efficient liposomal encapsulation of plasmid DNA
Jeffs, Lloyd B, Palmer, Lorne R, Ambegia, Ellen G, Giesbrecht, Cory, Ewanick, Shannon, MacLachlan, Ian
Published in Pharmaceutical research (01.03.2005)
Published in Pharmaceutical research (01.03.2005)
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Lipid Encapsulation Enables the Effective Systemic Delivery of Polyplex Plasmid DNA
Heyes, James, Palmer, Lorne, Chan, Kitty, Giesbrecht, Cory, Jeffs, Lloyd, MacLachlan, Ian
Published in Molecular therapy (01.04.2007)
Published in Molecular therapy (01.04.2007)
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RNAi-mediated gene silencing in non-human primates
Wheat, Amanda J, Vornlocher, Hans-Peter, Röhl, Ingo, Lam, Kieu, McClintock, Kevin, Koteliansky, Victor, Yaworski, Ed, Jeffs, Lloyd B, MacLachlan, Ian, Soutschek, Jürgen, Toudjarska, Ivanka, Palmer, Lorne R, Heyes, James A, Zedalis, William, Akinc, Akin, Lee, Amy C. H, Bumcrot, David, Manoharan, Muthiah, Judge, Adam D, Racie, Timothy, Shanmugam, Sumi, Sood, Vandana, Seiffert, Stephan, Bramlage, Birgit, Fedoruk, Matthew N, Harborth, Jens, Zimmermann, Tracy S, John, Matthias, Nechev, Lubomir V
Published in Nature (04.05.2006)
Published in Nature (04.05.2006)
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Relationships between fungal spore morphologies and surface properties for entomopathogenic members of the general Beauveria, Metarhizium, Paecilomyces,Tolypocladium, and Verticillium
Jeffs, Lloyd B., Xavier, Ilungo J., Matai, Russell E., Khachatourians, George G.
Published in Canadian journal of microbiology (1999)
Published in Canadian journal of microbiology (1999)
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Abstract B204: Development of ALN-VSP: An RNAi therapeutic for liver malignancies
Toudjarska, Iva, Judge, Adam, Buck, Tim, McClintock, Kevin, de Jong, Susan, Ambegia, Ellen, Brodsky, Joshua, Akinc, Akin, Racie, Timothy, Jeffs, Lloyd, Yaworski, Ed, MacLachlan, Ian, Sah, Dinah W., Gollob, Jared, Bumcrot, David A.
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY
MacLachlan, Ian, Jeffs, Lloyd, Palmer, Lorne, Yaworski, Edward, Lam, Kieu
Year of Publication 23.11.2023
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Year of Publication 23.11.2023
Patent
LIPID NANOPARTICLE FORMULATIONS FOR VACCINES
CHAKRAPANI, Harish, ZHANG, Ruo Yu, JAIN, Nikita, HARVIE, Pierrot, KAZEMIAN, Mohammadreza, JEFFS, Lloyd, THOMAS, Anitha
Year of Publication 04.01.2024
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Year of Publication 04.01.2024
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Novel lipid formulations for nucleic acid delivery
Palmer Lorne R, Jeffs, Lloyd B, Maclachlan, Ian, Yaworski, Edward, Lam, Kieu
Year of Publication 30.11.2023
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Year of Publication 30.11.2023
Patent
Lipid formulations for nucleic acid delivery
MacLachlan, Ian, Jeffs, Lloyd, Palmer, Lorne, Yaworski, Edward, Lam, Kieu
Year of Publication 12.10.2021
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Year of Publication 12.10.2021
Patent