Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity
Brents, Lisa K, Reichard, Emily E, Zimmerman, Sarah M, Moran, Jeffery H, Fantegrossi, William E, Prather, Paul L
Published in PloS one (06.07.2011)
Published in PloS one (06.07.2011)
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Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids
Seely, Kathryn A., Lapoint, Jeff, Moran, Jeffery H., Fattore, Liana
Published in Progress in neuro-psychopharmacology & biological psychiatry (03.12.2012)
Published in Progress in neuro-psychopharmacology & biological psychiatry (03.12.2012)
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Forensic investigation of K2, Spice, and “bath salt” commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds
Seely, Kathryn A, Patton, Amy L, Moran, Cindy L, Womack, Mary L, Prather, Paul L, Fantegrossi, William E, Radominska-Pandya, Anna, Endres, Gregory W, Channell, Kermit B, Smith, Nathaniel H, McCain, Keith R, James, Laura P, Moran, Jeffery H
Published in Forensic science international (10.12.2013)
Published in Forensic science international (10.12.2013)
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Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
Brents, Lisa K., Gallus-Zawada, Anna, Radominska-Pandya, Anna, Vasiljevik, Tamara, Prisinzano, Thomas E., Fantegrossi, William E., Moran, Jeffery H., Prather, Paul L.
Published in Biochemical pharmacology (01.04.2012)
Published in Biochemical pharmacology (01.04.2012)
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Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands
Chimalakonda, Krishna C, Seely, Kathryn A, Bratton, Stacie M, Brents, Lisa K, Moran, Cindy L, Endres, Gregory W, James, Laura P, Hollenberg, Paul F, Prather, Paul L, Radominska-Pandya, Anna, Moran, Jeffery H
Published in Drug metabolism and disposition (01.11.2012)
Published in Drug metabolism and disposition (01.11.2012)
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K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure
Patton, Amy L., Chimalakonda, Krishna C., Moran, Cindy L., McCain, Keith R., Radominska‐Pandya, Anna, James, Laura P., Kokes, Charles, Moran, Jeffery H.
Published in Journal of forensic sciences (01.11.2013)
Published in Journal of forensic sciences (01.11.2013)
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Journal Article
Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors
Rajasekaran, Maheswari, Brents, Lisa K., Franks, Lirit N., Moran, Jeffery H., Prather, Paul L.
Published in Toxicology and applied pharmacology (01.06.2013)
Published in Toxicology and applied pharmacology (01.06.2013)
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Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine
Moran, Cindy L, Le, Vi-Huyen, Chimalakonda, Krishna C, Smedley, Amy L, Lackey, Felisia D, Owen, Suzanne N, Kennedy, Paul D, Endres, Gregory W, Ciske, Fred L, Kramer, James B, Kornilov, Andrei M, Bratton, L. D, Dobrowolski, Paul J, Wessinger, William D, Fantegrossi, William E, Prather, Paul L, James, Laura P, Radominska-Pandya, Anna, Moran, Jeffery H
Published in Analytical chemistry (Washington) (01.06.2011)
Published in Analytical chemistry (Washington) (01.06.2011)
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Hands-Free Analytical Urine Testing Technology Validated for Drug-Facilitated Crime Investigations
Avram, Marina, Bodinger, Carter A., Clark, Madeline A., Stuckey, Daniel G., Mathews, Samuel E., Stogsdill, Susan N., Barna, Elyse C., Williams, David K., McGill, Mitchell, Fantegrossi, William E., Liebelt, Erica L., James, Laura P., Endres, Gregory W., Moran, Jeffery H.
Published in Chemical research in toxicology (13.09.2023)
Published in Chemical research in toxicology (13.09.2023)
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Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Janganati, Venumadhav, Salazar, Paloma, Parks, Brian J, Gorman, Gregory S, Prather, Paul L, Peterson, Eric C, Alund, Alexander W, Moran, Jeffery H, Crooks, Peter A, Brents, Lisa K
Published in Frontiers in pharmacology (09.05.2023)
Published in Frontiers in pharmacology (09.05.2023)
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Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine
Chimalakonda, Krishna C, Moran, Cindy L, Kennedy, Paul D, Endres, Gregory W, Uzieblo, Adam, Dobrowolski, Paul J, Fifer, E. Kim, Lapoint, Jeff, Nelson, Lewis S, Hoffman, Robert S, James, Laura P, Radominska-Pandya, Anna, Moran, Jeffery H
Published in Analytical chemistry (Washington) (15.08.2011)
Published in Analytical chemistry (Washington) (15.08.2011)
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Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants
Patton, Amy L., Seely, Kathryn A., Yarbrough, Azure L., Fantegrossi, William, James, Laura P., McCain, Keith R., Fujiwara, Ryoichi, Prather, Paul L., Moran, Jeffery H., Radominska-Pandya, Anna
Published in Biochemical and biophysical research communications (06.04.2018)
Published in Biochemical and biophysical research communications (06.04.2018)
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Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids
MAZUR, Anna, LICHTI, Cheryl F, PRATHER, Paul L, ZIELINSKA, Agnieszka K, BRATTON, Stacie M, GALLUS-ZAWADA, Anna, FINEL, Moshe, MILLER, Grover P, RADOMINSKA-PANDYA, Anna, MORAN, Jeffery H
Published in Drug metabolism and disposition (01.07.2009)
Published in Drug metabolism and disposition (01.07.2009)
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In Utero Exposure to Norbuprenorphine, a Major Metabolite of Buprenorphine, Induces Fetal Opioid Dependence and Leads to Neonatal Opioid Withdrawal Syndrome
Griffin, Bryce A, Caperton, Caitlin O, Russell, Lauren N, Cabanlong, Christian V, Wilson, Catheryn D, Urquhart, Kyle R, Martins, Bradford S, Zita, Marcelle Dina, Patton, Amy L, Alund, Alexander W, Owens, S Michael, Fantegrossi, William E, Moran, Jeffery H, Brents, Lisa K
Published in The Journal of pharmacology and experimental therapeutics (01.07.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2019)
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A Major Glucuronidated Metabolite of JWH-018 Is a Neutral Antagonist at CB1 Receptors
Seely, Kathryn A, Brents, Lisa K, Radominska-Pandya, Anna, Endres, Gregory W, Keyes, Gregory S, Moran, Jeffery H, Prather, Paul L
Published in Chemical research in toxicology (16.04.2012)
Published in Chemical research in toxicology (16.04.2012)
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Quantitative Measurement of Acetyl Fentanyl and Acetyl Norfentanyl in Human Urine by LC-MS/MS
Patton, Amy L, Seely, Kathryn A, Pulla, Sharon, Rusch, Nancy J, Moran, Cindy L, Fantegrossi, William E, Knight, Laura D, Marraffa, Jeanna M, Kennedy, Paul D, James, Laura P, Endres, Gregory W, Moran, Jeffery H
Published in Analytical chemistry (Washington) (04.02.2014)
Published in Analytical chemistry (Washington) (04.02.2014)
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Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
CHIMALAKONDA, Krishna C, BRATTON, Stacie M, LE, Vi-Huyen, KAN HUI YIEW, DINEVA, Anna, MORAN, Cindy L, JAMES, Laura P, MORAN, Jeffery H, RADOMINSKA-PANDYA, Anna
Published in Drug metabolism and disposition (01.10.2011)
Published in Drug metabolism and disposition (01.10.2011)
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