Predicting Antibody Developability Profiles Through Early Stage Discovery Screening
Bailly, Marc, Mieczkowski, Carl, Juan, Veronica, Metwally, Essam, Tomazela, Daniela, Baker, Jeanne, Uchida, Makiko, Kofman, Ester, Raoufi, Fahimeh, Motlagh, Soha, Yu, Yao, Park, Jihea, Raghava, Smita, Welsh, John, Rauscher, Michael, Raghunathan, Gopalan, Hsieh, Mark, Chen, Yi-Ling, Nguyen, Hang Thu, Nguyen, Nhung, Cipriano, Dan, Fayadat-Dilman, Laurence
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS
Flanagan, Ken, Fitzgerald, Kent, Baker, Jeanne, Regnstrom, Karin, Gardai, Shyra, Bard, Frederique, Mocci, Simonetta, Seto, Pui, You, Monica, Larochelle, Catherine, Prat, Alexandre, Chow, Samuel, Li, Lauri, Vandevert, Chris, Zago, Wagner, Lorenzana, Carlos, Nishioka, Christopher, Hoffman, Jennifer, Botelho, Raquel, Willits, Christopher, Tanaka, Kevin, Johnston, Jennifer, Yednock, Ted
Published in PloS one (06.07.2012)
Published in PloS one (06.07.2012)
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Characterization and Modeling of Reversible Antibody Self-Association Provide Insights into Behavior, Prediction, and Correction
Mieczkowski, Carl, Cheng, Alan, Fischmann, Thierry, Hsieh, Mark, Baker, Jeanne, Uchida, Makiko, Raghunathan, Gopalan, Strickland, Corey, Fayadat-Dilman, Laurence
Published in Antibodies (Basel) (15.02.2021)
Published in Antibodies (Basel) (15.02.2021)
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Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies
Mieczkowski, Carl, Bahmanjah, Soheila, Yu, Yao, Baker, Jeanne, Raghunathan, Gopalan, Tomazela, Daniela, Hsieh, Mark, McCoy, Mark, Strickland, Corey, Fayadat-Dilman, Laurence
Published in Antibodies (Basel) (22.11.2020)
Published in Antibodies (Basel) (22.11.2020)
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Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target
Regnström, Karin, Yan, Jiangli, Nguyen, Lan, Callaway, Kari, Yang, Yanli, Diep, Linnea, Xing, Weimei, Adhikari, Anirban, Beroza, Paul, Hom, Roy K, Riley, Brigit, Rudolph, Don, Jobling, Michael F, Baker, Jeanne, Johnston, Jennifer, Konradi, Andrei, Bova, Michael P, Artis, Dean R, Artis, Rick D
Published in PloS one (05.07.2013)
Published in PloS one (05.07.2013)
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Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors
Bowers, Simeon, Truong, Anh P., Ye, Michael, Aubele, Danielle L., Sealy, Jennifer M., Neitz, R. Jeffrey, Hom, Roy K., Chan, Wayman, Dappen, Michael S., Galemmo, Robert A., Konradi, Andrei W., Sham, Hing L., Zhu, Yong L., Beroza, Paul, Tonn, George, Zhang, Heather, Hoffman, Jennifer, Motter, Ruth, Fauss, Donald, Tanaka, Pearl, Bova, Michael P., Ren, Zhao, Tam, Danny, Ruslim, Lany, Baker, Jeanne, Pandya, Deepal, Diep, Linnea, Fitzgerald, Kent, Artis, Dean R., Anderson, John P., Bergeron, Marcelle
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Regulated Expression of the Receptor-Like Tyrosine Phosphatase CD148 on Hemopoietic Cells
Lin, Joseph, Zhu, Jing W, Baker, Jeanne E, Weiss, Arthur
Published in The Journal of immunology (1950) (15.08.2004)
Published in The Journal of immunology (1950) (15.08.2004)
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Protein Tyrosine Phosphatase CD148-Mediated Inhibition of T-Cell Receptor Signal Transduction Is Associated with Reduced LAT and Phospholipase Cγ1 Phosphorylation
Baker, Jeanne E., Majeti, Ravindra, Tangye, Stuart G., Weiss, Arthur
Published in Molecular and Cellular Biology (01.04.2001)
Published in Molecular and Cellular Biology (01.04.2001)
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Aldehyde Tag Coupled with HIPS Chemistry Enables the Production of ADCs Conjugated Site-Specifically to Different Antibody Regions with Distinct in Vivo Efficacy and PK Outcomes
Drake, Penelope M, Albers, Aaron E, Baker, Jeanne, Banas, Stefanie, Barfield, Robyn M, Bhat, Abhijit S, de Hart, Gregory W, Garofalo, Albert W, Holder, Patrick, Jones, Lesley C, Kudirka, Romas, McFarland, Jesse, Zmolek, Wes, Rabuka, David
Published in Bioconjugate chemistry (16.07.2014)
Published in Bioconjugate chemistry (16.07.2014)
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Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion
Holder, Patrick G., Jones, Lesley C., Drake, Penelope M., Barfield, Robyn M., Bañas, Stefanie, de Hart, Gregory W., Baker, Jeanne, Rabuka, David
Published in The Journal of biological chemistry (19.06.2015)
Published in The Journal of biological chemistry (19.06.2015)
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Exploring the effects of linker composition on site-specifically modified antibody–drug conjugates
Albers, Aaron E., Garofalo, Albert W., Drake, Penelope M., Kudirka, Romas, de Hart, Gregory W., Barfield, Robyn M., Baker, Jeanne, Banas, Stefanie, Rabuka, David
Published in European journal of medicinal chemistry (17.12.2014)
Published in European journal of medicinal chemistry (17.12.2014)
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Abstract 577: Antagonism of the co-inhibitory receptor BTLA enhances efficacy of anti-PD-1 treatment in murine syngeneic tumor models
Miselis, Nathan R., Linn, Douglas, Restaino, Clifford, Baral, Toya, Xia, Jane, Ueda, Roanna, Sawant, Anandi, Baker, Jeanne, Raghunathan, Gopalan, Wang1, Xinzhong, Bowman, Edward, Sukumar, Selvakumar
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with copper(II)
York, Dona, Baker, Jeanne, Holder, Patrick G, Jones, Lesley C, Drake, Penelope M, Barfield, Robyn M, Bleck, Gregory T, Rabuka, David
Published in BMC biotechnology (24.02.2016)
Published in BMC biotechnology (24.02.2016)
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Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy
Guelen, Lars, Fischmann, Thierry O, Wong, Jerelyn, Mauze, Smita, Guadagnoli, Marco, Bąbała, Nikolina, Wagenaars, Jozef, Juan, Veronica, Rosen, David, Prosise, Winnie, Habraken, Maurice, Lodewijks, Imke, Gu, Danling, Stammen-Vogelzangs, Judith, Yu, Ying, Baker, Jeanne, Lutje Hulsik, David, Driessen-Engels, Lilian, Malashock, Dan, Kreijtz, Joost, Bertens, Astrid, de Vries, Evert, Bovens, Astrid, Bramer, Arne, Zhang, Yiwei, Wnek, Richard, Troth, Sean, Chartash, Elliot, Dobrenkov, Konstantin, Sadekova, Svetlana, van Elsas, Andrea, Cheung, Jason K, Fayadat-Dilman, Laurence, Borst, Jannie, Beebe, Amy M, Van Eenennaam, Hans
Published in Journal for immunotherapy of cancer (01.09.2022)
Published in Journal for immunotherapy of cancer (01.09.2022)
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Development of an enzyme-linked immunosorbent assay (ELISA) to measure the level of tyrosine hydroxylase protein in brain tissue from Parkinson's disease models
Fauss, Donald, Motter, Ruth, Dofiles, Lilibeth, Rodrigues, Maria Armanda Viana, You, Monica, Diep, Linnea, Yang, Yangli, Seto, Pui, Tanaka, Kevin, Baker, Jeanne, Bergeron, Marcelle
Published in Journal of neuroscience methods (15.05.2013)
Published in Journal of neuroscience methods (15.05.2013)
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Toward Better Access to Full-Text Aggregator Collections
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Conference Proceeding
Selective and Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors That Reduce -Synuclein Phosphorylation in Rat Brain
Aubele, Danielle L., Hom, Roy K., Adler, Marc, Galemmo, Robert A., Bowers, Simeon, Truong, Anh P., Pan, Hu, Beroza, Paul, Neitz, R. Jeffrey, Yao, Nanhua, Lin, May, Tonn, George, Zhang, Heather, Bova, Michael P., Ren, Zhao, Tam, Danny, Ruslim, Lany, Baker, Jeanne, Diep, Linnea, Fitzgerald, Kent, Hoffman, Jennifer, Motter, Ruth, Fauss, Donald, Tanaka, Pearl, Dappen, Michael, Jagodzinski, Jacek, Chan, Wayman, Konradi, Andrei W., Latimer, Lee, Zhu, Yong L., Sham, Hing L., Anderson, John P., Bergeron, Marcelle, Artis, Dean R.
Published in ChemMedChem (01.08.2013)
Published in ChemMedChem (01.08.2013)
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Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid β-related Behavioral Deficits in a Mouse Model of Alzheimer Disease
Basi, Guriqbal S., Feinberg, Hadar, Oshidari, Farshid, Anderson, John, Barbour, Robin, Baker, Jeanne, Comery, Thomas A., Diep, Linnea, Gill, Davinder, Johnson-Wood, Kelly, Goel, Amita, Grantcharova, Katerina, Lee, Mike, Li, Jingzhi, Partridge, Anthony, Griswold-Prenner, Irene, Piot, Nicolas, Walker, Don, Widom, Angela, Pangalos, Menelas N., Seubert, Peter, Jacobsen, J. Steven, Schenk, Dale, Weis, William I.
Published in The Journal of biological chemistry (29.01.2010)
Published in The Journal of biological chemistry (29.01.2010)
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